- Electric and Hybrid Vehicle Technologies
- Railway Systems and Energy Efficiency
- Advanced Combustion Engine Technologies
- Biodiesel Production and Applications
- Vehicle emissions and performance
- Electrical Contact Performance and Analysis
- Photopolymerization techniques and applications
- Catalytic Processes in Materials Science
- Innovative Microfluidic and Catalytic Techniques Innovation
- Microfluidic and Capillary Electrophoresis Applications
- Hepatitis C virus research
- Advanced Polymer Synthesis and Characterization
- Analytical Chemistry and Chromatography
- Liver Disease and Transplantation
- Combustion and flame dynamics
- Marine Biology and Ecology Research
- Pharmacogenetics and Drug Metabolism
- Estrogen and related hormone effects
- Surface Modification and Superhydrophobicity
- Corporate Finance and Governance
- Advanced Battery Technologies Research
- Liver Disease Diagnosis and Treatment
- Immune Cell Function and Interaction
- Hepatitis B Virus Studies
- Monoclonal and Polyclonal Antibodies Research
University of California, Santa Barbara
2025
Hitachi (Japan)
1979-2024
The University of Tokyo
1989-2023
Tokyo University of the Arts
2022-2023
Eneos (Japan)
1995-2011
Tohoku University
2002-2006
Jichi Medical University
1995-2005
RIKEN
2005
Yokohama City University
2000
Juntendo University
2000
Cytotoxic T lymphocytes have been reported to be involved in the immune clearance of virus-infected cells and pathogenesis viral infection. We studied cytotoxic lymphocyte response putative nucleocapsid protein hepatitis C virus patients with chronic C. specific for were generated from peripheral blood by means repeated stimulation a synthetic peptide. The CD8 positive recognized an epitope residues 81 100 association human leukocyte antigen class I molecule, B44. peptide-induced target...
We postulated that intensification of chemotherapy immediately after remission induction might reduce the leukemic cell burden sufficiently to allow an abbreviated period antimetabolite therapy.Three hundred forty-seven children (ages 1 15 years) with previously untreated acute lymphoblastic leukemia (ALL) were enrolled onto Tokyo L92-13 study, which excluded patients mature B-cell ALL and less than year old. One twenty-four classified as standard risk, 122 high 101 extremely according age,...
Partition coefficients of hydrophilic organic solvents (C1-C5 acetate esters and alcohols) in distilled water, olive oil, human blood, various rat tissues (blood, liver, kidney, brain, muscle, fat) were determined. Water/air partition measured by a new vial equilibration technique, which needs no direct measurement the concentration either liquid phase or gas phase, but only chromatographic peak areas from both phases. Once water/air had been measured, blood/air, oil/air, tissue/air could be...
Early-career researchers from around the world summarize recent developments and present visions for future of vat photopolymerization 3D printing.
All-trans-3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid (designated "acyclic retinoid") induced upregulation of the albumin gene expression at its transcriptional level, whereas all-trans-retinoic (RA) downregulation in both PLC/PRF/5 and HuH7 human hepatoma cell lines. These up- down regulations coordinated with high low levels mRNA for hepatocyte nuclear factor-1 (HNF-1), which is one most potent transcription factors gene, implying that retinoids may regulate through HNF-1...
Photopolymerization and photoprocessing are core technologies for molding tuning polymer materials. However, they incompatible with single materials owing to their contradictory photoreactivity. Herein, an acid-induced photocleavable crosslinker, a platinum-acetylide complex covered by permethylated cyclodextrins, enables the fabrication of photoprocessable via photopolymerization N-(2-hydroxyethyl)acrylamide. The networks molded 365 nm irradiation as well softened degraded cooperative...
Abstract Although photodegradability is promising for on‐demand tuning of material properties, phototuned materials cannot be utilized under ambient light irradiation owing to their photoinstability. Herein, a novel photostable gel that photodegrades only in the presence an acid fabricated. The unique reactivity supramolecular platinum‐acetylide complex uncovered incorporate into poly(methyl methacrylate) as cross‐linker exhibit softening and swelling simultaneous treatment with UV‐light...
Twenty-two patients with hepatocellular carcinoma were treated by a new method of transcatheter arterial chemoembolization using an autologous blood clot as embolizing agent. All had underlying advanced cirrhosis (14 Child's class B and 8 C patients). The median follow-up interval was 11 mo (range = 2 to 30 mo). results the treatment compared those conventional gelatin sponge particles for 19 historical controls. survival rate procedure estimated Kaplan-Meier 100% at yr, whereas 89% 1 yr 72%...
A T-cell helper for generation of hepatitis C virus-specific cytotoxic T lymphocytes was studied in three patients with chronic C. In all three, human leukocyte antigen B44-restricted recognizing an epitope virus nucleocapsid protein residues 81-100 were generated from the peripheral blood by repeated stimulation a synthetic peptide. The proliferative response to 1-120 observed one patient, and ascribed CD4+ cells. cells recognized major 21-40 minor epitope(s) 81-110. They produced...
The expression of androgen receptor messenger RNA in hepatocellular carcinomas and hepatoma cell lines was studied using Northern-blot analysis the complementary DNA—polymerase chain reaction method. Androgen RNAs were detected (although low levels) both carcinoma tissues noncancerous liver all eight cases we studied, except for tumor sample one case. None however, expressed detectable levels SKHEP-1 line. (HEPATOLOGY 1991;14:99-102.)
The temperature rise of the traction battery installed on a battery-powered EMU is easily able to be estimated by an equivalent thermal circuit model. However, accuracy temperatures depends parameters (thermal capacities and resistances) used in To obtain proper easily, automatic parameter-identification algorithm based gradient method was developed this paper. parameter identification conducted only using measured current curves system obtained during test running. model method, effect...