A5085130854- Connexins and lens biology
- Nicotinic Acetylcholine Receptors Study
- Heat shock proteins research
- Ion channel regulation and function
- Transportation Planning and Optimization
- Yersinia bacterium, plague, ectoparasites research
- Robotics and Sensor-Based Localization
- Supercapacitor Materials and Fabrication
- Electrical Fault Detection and Protection
- Advanced battery technologies research
- Advancements in Battery Materials
- Retinal Imaging and Analysis
- QR Code Applications and Technologies
- Photonic and Optical Devices
- Urban and Freight Transport Logistics
- Cardiac electrophysiology and arrhythmias
- Topic Modeling
- Maritime Ports and Logistics
- Advanced Optical Network Technologies
- Plant Diversity and Evolution
- Virology and Viral Diseases
- Plant Virus Research Studies
- Circular RNAs in diseases
- Flavonoids in Medical Research
- Optical Network Technologies
Chinese Academy of Sciences
2024
University of Chinese Academy of Sciences
2024
Beijing Botanical Garden
2024
Southeast University
2024
South China University of Technology
2022-2024
The Affiliated Yongchuan Hospital of Chongqing Medical University
2021-2024
Chongqing Medical University
2021-2024
China National Botanical Garden
2024
Wuhan University of Technology
2017-2024
Institute of Botany
2024
A novel composite anode is prepared by mixing zinc particles with activated carbon (AC) to improve the cycle performance of neutral rechargeable ion batteries. Galvanostatic charge/discharge cycling tests indicate that capacity retention cell adding 12 wt% in Zn 85.6% after 80 cycles, which much higher than 56.7% for using unmodified anode. X-ray diffraction analysis indicates addition can suppress formation inactive basic sulfates (Zn4SO4(OH)6·nH20). Morphology, elemental mapping and N2...
Abstract Background Although anxiety disorders are one of the most prevalent mental disorders, their underlying biological mechanisms have not yet been fully elucidated. In recent years, genetically determined metabolites (GDMs) used to reveal disorders. However, this strategy has applied Herein, we explored causality GDMs on through Mendelian randomization study, with overarching goal unraveling mechanisms. Methods A two-sample (MR) analysis was implemented assess genome-wide association...
Abstract The use of electricity generated from clean and renewable sources, such as water, wind, or sunlight, requires efficiently distributed electrical energy storage by high-power high-energy secondary batteries using abundant, low-cost materials in sustainable processes. American Science Policy Reports state that the next-generation “beyond-lithium” battery chemistry is one feasible solution for goals. Here we discover new “multivalent ion” beyond lithium chemistry. Through theoretic...
Abstract Flexible asymmetric supercapacitors with excellent electrochemical performance and aesthetic property are realized by using ultrathin two-dimensional (2D) MnO 2 graphene nanosheets as cathode anode materials, respectively. 2D (MSs) a thickness of ca. nm synthesized soft template method for the first time, which achieve high specific capacitance 774 F g −1 even after 10000 cycles. Asymmetric based on MSs exhibit very energy density up to 97.2 Wh kg no more than 3% loss cycles in...
Purpose To establish and validate a universal artificial intelligence (AI) platform for collaborative management of cataracts involving multilevel clinical scenarios explored an AI-based medical referral pattern to improve efficiency resource coverage. Methods The training validation datasets were derived from the Chinese Medical Alliance Artificial Intelligence, covering healthcare facilities capture modes. labelled using three-step strategy: (1) mode recognition; (2) cataract diagnosis as...
While vocal tract resonances (VTRs, or formants that are defined as such resonances) known to play a critical role in human speech perception and computer processing, there has been lack of standard databases needed for the quantitative evaluation automatic VTR extraction techniques. We report this paper on our recent effort create publicly available database first three frequency trajectories. The contains representative subset TIMIT corpus with respect speaker, gender, dialect phonetic...
Calmodulin (CaM) has been implicated in mediating the Ca(2+)-dependent regulation of gap junctions. This report identifies a CaM-binding motif comprising residues 136-158 intracellular loop Cx43. A 23-mer peptide encompassing this was shown to bind Ca(2+)-CaM with 1:1 stoichiometry by using various biophysical approaches, including surface plasmon resonance, circular dichroism, fluorescence spectroscopy, and NMR. Far UV dichroism studies indicated that Cx43-derived increased its...
Calmodulin (CaM) binding sites were recently identified on the cytoplasmic loop (CL) of at least three α-subfamily connexins (Cx43, Cx44, Cx50), while Cx40 does not have this putative CaM domain. The purpose study was to examine functional relevance Cx43 site Ca(2+)-dependent regulation gap junction proteins formed by and Cx40. Dual whole cell patch-clamp experiments performed stable murine Neuro-2a cells expressing or Addition ionomycin increase external Ca(2+) influx reduced conductance...
Gut microbiota (GM) dysbiosis and dysregulated bile acids (BAs) metabolism have been linked to ulcerative colitis (UC) pathogenesis. The possibility of utilizing live probiotics with a defined BAs-metabolizing capability modify the composition BAs for UC treatment remains unexplored.
Abstract High-voltage cables play a vital role in urban power transmission. However, can become defective during operation due to corrosion, aging, etc., which lead outages, fires, and other accidents. The time-frequency domain reflection method is cable detection method, but it uses signal that difficult calculate the wave speed continuously changing frequency characteristics, errors determination. In this paper, transmission model considering effects of attenuation will be established...
Abstract The outer sheath of high voltage cables is the “first line defence”, preventing internal structure cable from being damaged in first place. However, during operation, can break due to termite erosion, external stress, and other factors. In order detect broken state high-voltage improve stability reliability power grid this paper proposes detection method for identification localization fault point cables. First, it establishes a model characteristic impedance cables’ distribution...
Cx50 (connexin50), a member of the α-family gap junction proteins expressed in lens eye, has been shown to be essential for normal development. In present study, we identified CaMBD [CaM (calmodulin)-binding domain] (residues 141–166) intracellular loop Cx50. Elevations Ca2+ concentration effected 95% decline gj (junctional conductance) N2a cells that is likely mediated by CaM, because inclusion CaM inhibitor calmidazolium prevented this Ca2+-dependent decrease gj. The direct involvement...
Understanding the pathogenesis of nigral dopaminergic neurodegeneration is critical for developing mechanism-based treatments Parkinson's disease (PD). In neurons postmortem human PD brains, we found that CREB, a well-recognized pro-survival transcription factor in neurons, was inactivated by dephosphorylation at Ser133. CREB correlated with decreased expression NURR1, one its target genes crucial neuron survival, confirming function impaired PD. An MPTP mouse model used to further elucidate...
Stromal interaction molecule 1 (STIM1) is responsible for activating the Ca 2+ release‐activated (CRAC) channel by first sensing changes in concentration endoplasmic reticulum ([Ca ] ER ) via its luminal canonical EF‐hand motif and subsequently oligomerizing to interact with CRAC pore‐forming subunit Orai1. In this work, we applied a grafting approach obtain intrinsic metal‐binding affinity of isolated STIM1, further investigated oligomeric state using pulsed‐field gradient NMR...
We present a one-step synthesis process for ultrathin non-crystalline MnO2 nanosheets. Their thickness is about 2 nm and the width varies from 5 to 20 nm. They induce higher capacitance than zero-dimensional spheres or one-dimensional rods. When heat treated at elevated temperature nanosheets partly grow into crystalline Mn2O3
Statement of RetractionWe, the Editors and Publisher journal Cell Cycle, have retracted following article:Min Yi, Xingping Dai, Qiuxia Li, Xia Xu, Yanyi Chen, Dongsheng Wang. Downregulated lncRNA CRNDE contributes to enhancement nerve repair after traumatic brain injury in rats. Cycle. 2019;18(18):2332-2343. doi: 10.1080/15384101.2019.1647024.Since publication, significant concerns been raised about integrity data reported results article. When approached for an explanation, authors did not...
Abstract The present study was designed to investigate the mechanism of traditional Chinese medicine Changqin NO. 1 on amelioration traumatic brain injury (TBI). Adult male C57BL/6J mice and newborn were used generate a mouse TBI model harvest primary neurons, respectively. localizations specific neural markers neuropilin-1 (Nrp-1), growth-associated protein-43 (GAP-43) microtubule-associated protein Tau (Tau) examined in tissues by immunohistochemistry. Terminal deoxynucleotidyl transferase...