A5103061747- Adipose Tissue and Metabolism
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Thermoregulation and physiological responses
- Fatty Acid Research and Health
- Regulation of Appetite and Obesity
- Parathyroid Disorders and Treatments
- Mitochondrial Function and Pathology
- Pancreatic function and diabetes
- Cancer-related Molecular Pathways
- Retinal Diseases and Treatments
- Genetics and Neurodevelopmental Disorders
- Peroxisome Proliferator-Activated Receptors
- Bariatric Surgery and Outcomes
- Acupuncture Treatment Research Studies
- Biochemical effects in animals
- Eicosanoids and Hypertension Pharmacology
- Burn Injury Management and Outcomes
- Adipokines, Inflammation, and Metabolic Diseases
- Ocular Diseases and Behçet’s Syndrome
- Cancer, Hypoxia, and Metabolism
- Hormonal and reproductive studies
- Liver Disease Diagnosis and Treatment
- Cancer Research and Treatments
- Phytoestrogen effects and research
- Hypothalamic control of reproductive hormones
First Affiliated Hospital of Xiamen University
2015-2024
Northwestern University
2013
The University of Texas Medical Branch at Galveston
2010
Evidence on the role of irisin in insulin resistance is limited and controversial, pathways between them remain unknown. We aimed to examine independent effects circulating different adiposity measurements, as well their potential interactions, resistance. also explore possible among irisin, adiposity, glucose levels A cross-sectional study 1,115 community- living obese Chinese adults, with data collection clinical characteristics, lipid metabolic parameters levels. Among subjects, 667 (59.8...
Polycystic ovary syndrome is a common endocrine disorder in females of reproductive age and believed to have developmental origin which gestational androgenization programs metabolic abnormalities offspring. During gestation, both male female fetuses are exposed potential androgen excess. In this study, we determined the consequences mice neonatal testosterone (NTM). Adult NTM displayed hypogonadotropic hypogonadism with decreased serum gonadotropin concentrations. Hypothalamic KiSS1 neurons...
Abstract Background Fetuin‐B impairs insulin action in myotubes and hepatocytes causes glucose intolerance mice. This study explored the correlation between serum fetuin‐B intrahepatic triglyceride (IHTG) content, association risk of resistance general adult population. Methods A cross‐sectional 1318 obese adults who underwent testing hepatic ultrasonography was conducted Xiamen, China. The IHTG content determined 428 subjects by magnetic resonance spectroscopy. Results Non‐alcoholic fatty...
Delayed gastric emptying is common following severe large cutaneous burns; however, the mechanisms of burn-induced delayed remain unknown. The aim this study was to explore possible involvement hyperglycemia and cyclooxygenase-2 receptors in dysrhythmias. Gastric slow waves were assessed rats 6 h sham or burn injury. Animals randomized one sham-burn seven groups: untreated; two groups saline treated (control); insulin (5 IU/kg); inhibitor (10 mg/kg); ghrelin (2 nmol/rat); electrical...
High fat diet (HFD)-induced obesity triggers common features of human metabolic syndrome in rats. Our previous study showed that Fructus xanthii (FX) attenuates HFD-induced hepatic steatosis. The present was designed to investigate the effects FX on lipid metabolism epididymal (EF), and examine its underlying mechanisms. Aqueous extraction fractions or vehicle were orally administered by gavage for 6 weeks rats fed either a HFD normal chow (NCD). levels circulating free fatty acid (FFA)...
Damage to pancreatic β‑cells is closely associated with diabetes. However, the mechanism underlying injury remains unclear, although hypoxia considered as one of leading causes. Appoptosin a mitochondrial protein that promotes neuronal apoptosis. Studies conducted on appoptosin thus far have primarily focused Alzheimer's disease, and demonstrated expression significantly increased in ischemic‑reperfused rat brains, which indicates its close association hypoxia. role β‑cells, are sensitive...
We aimed to explore the association of plasma TP53-induced glycolysis and apoptosis regulator (TIGAR) level with colorectal cancer (CRC) metastasis.A cross-sectional study 126 CRC patients was conducted in Xiamen, China. Multivariable logistic regression used calculate adjusted OR 95% CIs TIGAR concentration for metastasis different models adjustment potential confounders. Area under curve (AUC) receiver operating characteristic (ROC) evaluate diagnostic value.CRC showed significantly...