A5100342040- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Liver physiology and pathology
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Drug-Induced Hepatotoxicity and Protection
- Respiratory viral infections research
- Nutrition and Health in Aging
- Autophagy in Disease and Therapy
- Gastroesophageal reflux and treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Traditional Chinese Medicine Studies
- Pharmacological Effects of Natural Compounds
- Organ Transplantation Techniques and Outcomes
- Frailty in Older Adults
- Cannabis and Cannabinoid Research
- Influenza Virus Research Studies
- Traditional Chinese Medicine Analysis
- Liver Diseases and Immunity
- Herpesvirus Infections and Treatments
- Esophageal and GI Pathology
- Heme Oxygenase-1 and Carbon Monoxide
- Reproductive System and Pregnancy
- Gastrointestinal disorders and treatments
- Tracheal and airway disorders
Wenzhou Medical University
2025
Ruian People's Hospital
2025
Second Affiliated Hospital of Xi'an Jiaotong University
2023-2024
Tianjin Medical University General Hospital
2016-2024
Guangzhou Medical University
2024
Second Affiliated Hospital of Guangzhou Medical University
2024
Tzu Chi University
2022
Changzhou Third People's Hospital
2017-2022
Hunan Provincial People's Hospital
2012-2022
Hualien Tzu Chi Medical Center
2022
Gestational diabetes mellitus (GDM) is a common metabolic disorder with important health implications for both mother and offspring. This study aims to assess the relationship between Triglyceride Glucose (TyG) index GDM explore its clinical significance. A retrospective cohort included 631 singleton pregnant women. The collected data on TyG index, glucose levels, outcomes from all participants. Research objectives were validated using logistic regression analysis Receiver Operating...
MicroRNA-21 (miR-21) has emerged as a critical regulatory molecule and an important serum marker in hepatic fibrogenesis. The aim of the present study was to investigate role inhibiting miR-21 on fibrosis treatment. Serum levels 60 healthy individuals 180 patients with different stages liver cirrhosis were examined, normal or cirrhotic human tissues (n=10 each) also detected. An adenoviral vector (Ad-TuD-21) carrying sponging ToughDecoy (TuD)-RNA sequence against constructed reduce...
Alterations in body compositions are related to poor outcomes and the presence of complications cirrhosis. However, no predictive tools combining all these anthropometric parameters applicable clinical setting. We aimed clarify potential utility develop a nomogram incorporating any independent factor for prognosticating long-term mortality cirrhosis.A total 414 patients were randomized into primary (n = 274) validation 140) cohorts. X-tile was performed identify optimal cut points...
Liver cirrhosis is characterized by immune dysfunction, contributing to malnutrition. We previously revealed neutrophil-to-lymphocyte ratio (NLR) as an indicator of disordered system. Herein we aimed (1) determine the optimal NLR cutoff that best predicts malnutrition risk and (2) clarify association between nutrition status.A total 135 hospitalized patients with were included. Immune dysfunction was evaluated levels serum C-reactive protein (CRP), NLR, other parameters. Malnutrition...
Previous studies have shown that sarcopenia appears to be a significant contributor physical frailty among outpatients with cirrhosis. However, the evidence is scant regarding relationship between and multi-dimensional inpatients. We aimed investigate potential contribution of in hospitalized patients cirrhosis sex-dependent manner.This cohort enrolled consecutive cirrhotics. Muscle quantity quality were assessed using computed tomography-based skeletal muscle index (SMI) intramuscular...
Peroral endoscopic myotomy (POEM) has emerged as an advanced technique for the treatment of achalasia, and defining learning curve is mandatory.From August 2011 to June 2014, two operators in our institution (A&B) carried out POEM on 35 33 consecutive patients, respectively. Moving average cumulative sum (CUSUM) methods were used analyze corrected operative time (cOT), referring duration per centimeter myotomy. Additionally, perioperative outcomes compared among distinct phases.Using moving...
This cross-sectional study investigated the prevalence and risk factors of high-risk human papilloma virus (HPV) infection, especially types 16 18, cervical neoplasia in female Inflammatory bowel disease (IBD) patients.From July 2014 to January 2017, sexually active, female, Chinese IBD patients (21-60 years) age-matched controls underwent ThinPrep cytology testing (TCT) HPV-DNA detection, completed questionnaires about awareness cancer HPV. Cervical dysplasia was categorized as...
Bicyclol, a novel synthetic antihepatitis drug, has been shown to protect against liver injury via various pharmacological activities. The purpose of the current study was further investigate protective effect bicyclol carbon tetrachloride (CCl4)-induced acute (ALI) and its underlying molecular mechanism, particularly autophagic machinery, anti-oxidative anti-inflammatory potentials. Our results found that treatment with significantly reduced CCl4-induced hepatotoxicity by alleviating...
Abstract Background Fetuin‐B impairs insulin action in myotubes and hepatocytes causes glucose intolerance mice. This study explored the correlation between serum fetuin‐B intrahepatic triglyceride (IHTG) content, association risk of resistance general adult population. Methods A cross‐sectional 1318 obese adults who underwent testing hepatic ultrasonography was conducted Xiamen, China. The IHTG content determined 428 subjects by magnetic resonance spectroscopy. Results Non‐alcoholic fatty...
Genipin, as the most effective ingredient of various traditional medications, encompasses antioxidative, anti-inflammatory, and antibacterial capacities. More recently, it is suggested that genipin protects against septic liver damage by restoring autophagy. The purpose current study was to explore protective effect carbon tetrachloride- (CCl 4 -) induced acute injury (ALI) its underlying molecular machinery. Our results indicated treatment with significantly reduced CCl -induced...