A5082781047- Parkinson's Disease Mechanisms and Treatments
- Neurological disorders and treatments
- Transcranial Magnetic Stimulation Studies
- Electroconvulsive Therapy Studies
- Obsessive-Compulsive Spectrum Disorders
- Botulinum Toxin and Related Neurological Disorders
- Advanced Neuroimaging Techniques and Applications
- Treatment of Major Depression
Amsterdam Neuroscience
2020-2024
Amsterdam University Medical Centers
2019-2024
University of Amsterdam
2020-2023
BackgroundNotwithstanding the large improvement in motor function Parkinson's disease (PD) patients treated with deep brain stimulation (DBS), apathy may increase. Postoperative cannot always be related to a dose reduction of dopaminergic medication and itself play role.ObjectiveWe studied whether DBS-treated PD could effect.MethodsIn 26 we acquired scores before >6 months after DBS subthalamic nucleus (STN). Magnetoencephalography recordings (ON OFF stimulation) were performed ≥6 placement....
Abstract Background Neuroimaging studies suggest an association between apathy after deep brain stimulation (DBS) and of the ventral part subthalamic nucleus (STN) due to associative fibers connected non-motor limbic circuits that are involved in emotion regulation motivation. We have previously described three patients with severe could be fully treated switching from a electrode contact point more dorsal point. Objectives To determine whether STN decreases compared standard care...
Background This study aims: (1) To compare cognitive and psychiatric outcomes after bilateral awake versus asleep subthalamic nucleus (STN) deep brain stimulation (DBS) surgery for Parkinson’s disease (PD). (2) explore the occurrence of diagnoses, impairment quality life in our whole sample. (3) validate whether we can predict postoperative decline. Methods 110 patients with PD were randomised to receive (n=56) or (n=54) STN DBS surgery. At baseline 6-month follow-up, all underwent...