A5068718073- Genetic factors in colorectal cancer
- Colorectal Cancer Treatments and Studies
- Cancer Genomics and Diagnostics
- Medical Malpractice and Liability Issues
- Mental Health Research Topics
- Patient Dignity and Privacy
- Prostate Cancer Treatment and Research
- Healthcare Decision-Making and Restraints
- Epigenetics and DNA Methylation
- Cancer-related molecular mechanisms research
- Global Health Workforce Issues
- Cancer, Lipids, and Metabolism
- Schizophrenia research and treatment
- Ethics in medical practice
- Functional Brain Connectivity Studies
- Innovations in Medical Education
- Treatment of Major Depression
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Psychedelics and Drug Studies
- Medical Education and Admissions
- Multiple and Secondary Primary Cancers
- Higher Education and Employability
- Sexual Assault and Victimization Studies
- Clinical Reasoning and Diagnostic Skills
- Data-Driven Disease Surveillance
Tergooi
2021-2024
University Medical Center Utrecht
2011-2022
Utrecht University
2021
St. Antonius Ziekenhuis
2013
La Roche College
2011
Hubrecht Institute for Developmental Biology and Stem Cell Research
2011
Erasmus University Rotterdam
2010
Erasmus MC
2010
In the era of DNA-guided personalized cancer treatment, it is essential to conduct predictive analysis on tissue that matters. Here, we analyzed genetic differences between primary colorectal adenocarcinomas (CRC) and their respective hepatic metastasis.The CRC subsequent metastasis 21 patients with were using targeted deep-sequencing DNA isolated from formalin-fixed, paraffin-embedded archived material.We have interrogated constitution a designed "Cancer Mini-Genome" consisting all exons...
ABSTRACT BACKGROUND Predicting outcomes in schizophrenia spectrum disorders is challenging due to the variability of individual trajectories. While machine learning (ML) shows promise outcome prediction, has not yet been integrated into clinical practice. Understanding how ML models (MLMs) can complement psychiatrists’ predictions and bridge gap between MLM capabilities practical use key. OBJECTIVE This study aims compare performance psychiatrists MLMs predicting short-term symptomatic...
Negative content of auditory verbal hallucinations (AVH) is a strong predictor distress and impairment. This paper quantifies emotional voice-content in order to explore both subjective (i.e. perceived) objectively linguistic sentiment) measured negativity investigates associations with distress.Clinical non-clinical participants frequent AVH (n = 40) repeated recorded their verbatim directly upon hearing. The were analyzed for valence using Pattern, rule-based sentiment analyzer Dutch. the...
Program directors dismiss a small percentage of residents from residency training programs, presumably due to underperformance or lack progress. Whether in competency domains differs by residents' specialty is unknown.In 2021, we analysed the case law Dutch who were dismissed program director, and challenged this dismissal before national conciliation board between 2011 2020. Across medical specialties compared which CanMEDS these failed meet.We found 116 cases their programmes decision...
To study the frequency of observed cases disciplinary law complaints concerning transgressive behaviour in Dutch healthcare by analysing handled law.Retrospective review tribunals from period 1 January 2015 to 2020.Dutch healthcare.Descriptive retrospective study. All judgements at regional first instance 2020 were investigated. The following was studied: year judgement, number and nature complaints, type complainants, profession defendant.Over period, 139 about handled, 90 which involved...
Introduction Insufficient introspection as part of the 4I's model medical professionalism (introspection, integrity, interaction, and involvement) is considered an important impediment in trainees. How insufficient relates to decisions terminate residency training remains unclear. Insights into this subject provide opportunities improve professionals.
De #MeToo-beweging vergrootte de aandacht voor ongewenste intimiteiten in het algemeen aanzienlijk, maar specifieke onderzoek naar gedragingen van studenten Hoger Onderwijs was beperkt. Wij onderzochten instellingsmaatregelen opgelegd vanwege seksueel grensoverschrijdende door die ter discussie stonden bij College Beroep (CBHO). raadpleegden jurisprudentiedatabank CBHO een systematische content analyse uitspraken relevant blijven toekomstige procedures Raad State. databank bevat meer dan...
The significant increase in Internet availability has resulted a rise search queries on health-related topics. Previous research demonstrated the potential for analyzing web query volume nonpsychotropic prescription drugs, while studies psychotropic drugs remain scarce. aims of this study were to expand upon scarce knowledge by investigating relationship between volumes and antidepressants antipsychotics United Kingdom Netherlands gain insight topics concern, such as withdrawal symptoms...
<div>Abstract<p><b>Purpose:</b> In the era of DNA-guided personalized cancer treatment, it is essential to conduct predictive analysis on tissue that matters. Here, we analyzed genetic differences between primary colorectal adenocarcinomas (CRC) and their respective hepatic metastasis.</p><p><b>Experimental Design:</b> The CRC subsequent metastasis 21 patients with were using targeted deep-sequencing DNA isolated from formalin-fixed,...
<div>Abstract<p><b>Purpose:</b> In the era of DNA-guided personalized cancer treatment, it is essential to conduct predictive analysis on tissue that matters. Here, we analyzed genetic differences between primary colorectal adenocarcinomas (CRC) and their respective hepatic metastasis.</p><p><b>Experimental Design:</b> The CRC subsequent metastasis 21 patients with were using targeted deep-sequencing DNA isolated from formalin-fixed,...
3535 Background: In the era of personalized cancer treatment, patient selection to enrich for specific targets is key improve treatment outcome. Given genomic instability tumors in time we addressed whether analysis primary tumor or metastasis most suitable targeted treatment. Methods: With next generation (SOLiD 3+ system, Life Technologies) and sequencing (DNA capture-arrays, Agilent) have analyzed genetic environment a mini-genome–the exons 1,265 cancer-associated genes- its sequential...