A5101651959- Advanced Nanomaterials in Catalysis
- Nanoplatforms for cancer theranostics
- Advanced Photocatalysis Techniques
- Anomaly Detection Techniques and Applications
- Adsorption and biosorption for pollutant removal
- Artificial Immune Systems Applications
- Network Security and Intrusion Detection
- Advanced oxidation water treatment
- Nanomaterials for catalytic reactions
- Phosphorus and nutrient management
- Crystallization and Solubility Studies
- Electrochemical Analysis and Applications
- Advanced Clustering Algorithms Research
- Microplastics and Plastic Pollution
- Catalytic C–H Functionalization Methods
- Composting and Vermicomposting Techniques
- Advanced Image and Video Retrieval Techniques
- Catalytic Processes in Materials Science
- Electrochemical sensors and biosensors
- Ocular Surface and Contact Lens
- Advanced Synthetic Organic Chemistry
- Influenza Virus Research Studies
- Quinazolinone synthesis and applications
- Piperaceae Chemical and Biological Studies
- Recycling and Waste Management Techniques
Hunan University
2022-2025
Henan Provincial People's Hospital
2023-2024
Hunan University of Science and Engineering
2023-2024
Henan Provincial Eye Hospital
2023-2024
Zhengzhou University
2020-2024
Shanxi Medical University
2024
Fudan University
2023
Dartmouth College
2011-2022
Changzhou University
2022
Huangshan University
2020-2021
Handling clustering problems are important in data statistics, pattern recognition and image processing. The mean-shift algorithm, a common unsupervised algorithms, is widely used to solve problems. However, the algorithm restricted by its huge computational resource cost. In previous research [1], we proposed novel GPU-accelerated Faster Mean-shift which greatly speed up cosine-embedding problem. this study, extend improve handle Euclidean distance metrics. Different from conventional...
Dry eye disease (DED) is a major ocular pathology worldwide, causing serious discomfort and even visual impairment. The incidence of DED gradually increasing with the high-frequency use electronic products. Although inflammation core cause vicious cycle, reactive oxygen species (ROS) play pivotal role in cycle by regulating from upstream. Therefore, current therapies merely targeting show failure treatment. Here, novel dual-atom nanozymes (DAN)-based drops are developed. antioxidative DAN...
Abstract Efficiently removing excess reactive oxygen species (ROS) generated by various factors on the ocular surface is a promising strategy for preventing development of dry eye disease (DED). The currently available drops DED treatment are palliative, short-lived and frequently administered due to short precorneal residence time. Here, we developed nanozyme-based exploiting borate-mediated dynamic covalent complexation between n-FeZIF-8 nanozymes (n-Z(Fe)) poly(vinyl alcohol) (PVA)...
The development of non-antibiotic pharmaceuticals with biocompatible and efficient antibacterial properties is great significance for the treatment bacterial keratitis. In this study, we have developed iron-doped nanozymes (Fe
CeO2 with three different morphologies of nanorods (CeO2-r), particles (CeO2-p), and cubes (CeO2-c) was prepared, the guaiacol hydrodeoxygenation over their corresponding Co-based catalysts performed at 160–220 °C, 2 MPa, a H2 flow rate 80 mL/min, weight hourly space velocity 0.7 h–1. Compared Co/CeO2-p Co/CeO2-c, Co/CeO2-r has smaller Co particle sizes, higher Brunauer–Emmett–Teller surface area, larger amount active centers, oxygen vacancies, weak acid sites. These better physicochemical...
Video anomaly detection (VAD) has been intensively studied for years because of its potential applications in intelligent video systems. Existing unsupervised VAD methods tend to learn normality from training sets consisting only normal videos and regard instances deviating such as anomalies. However, they often consider local or global the temporal dimension. Some them focus on learning spatiotemporal representations consecutive frames enhance representation events. But powerful allows...
The incorporation of amide groups into biologically active molecules has been proven to be an efficient strategy for drug design and discovery. In this study, we present a simple practical method the synthesis amide-containing quinazolin-4(3H)-ones under transition-metal-free conditions. This is achieved through carbamoyl-radical-triggered cascade cyclization N3-alkenyl-tethered quinazolinones. Notably, carbamoyl radical generated in situ from oxidative decarboxylative process oxamic acids...
A simple, efficient, and practical method for the synthesis of S-quinolyl xanthates was developed via Ts2O-promoted deoxygenative C–H dithiocarbonation quinoline N-oxides with various potassium O-alkyl xanthates. The reaction performed well under transition-metal-free, base-free, room-temperature conditions wide substrate tolerance. Employing O-tert-butyl xanthate (tBuOCS2K) as a nucleophile, some valuable quinoline-2-thiones were unexpectedly obtained in one-pot without any additional base.
Lung cancer remains the tumor with highest global incidence and mortality rates. Current primary treatment modalities encompass targeted therapy, immunotherapy, chemotherapy; however, a subset of patients derives no benefit from these interventions. Recently, HER2-targeting antibody drug Disitamab vedotin (RC48) was approved introduced primarily for gastric bladder cancers, minimal investigation in field lung cancer. This study demonstrates that FOXA1 directly binds to promoter region HER2,...
Pathogenic microbial infections have been threatening public health all over the world, which makes it highly desirable to develop an antibiotics-free material for bacterial infection. In this paper, molybdenum disulfide (MoS 2 ) nanosheets loaded with silver nanoparticles (Ag NPs) were constructed inactive bacteria rapidly and efficiently in a short period under near infrared (NIR) laser (660 nm) presence of H O . The designed presented favorable features peroxidase-like ability...
Cordycepin has been successfully used as a natural anti-cancer drug, but it is rapidly metabolized in vivo. Nanoencapsulation thus promising method to improve its bioavailability. In this study, we adopted green synthesis process develop novel self-assembling phycocyanin-dextran-cordycepin (Phy-Dex-Cord) micelles for efficient cordycepin encapsulation and delivery. We first the Maillard reaction graft dextran onto phycocyanin, forming phycocyanin-dextran complex. Through self-assembly of...