A5087838322- Skin Protection and Aging
- Contact Dermatitis and Allergies
- Dermatology and Skin Diseases
- Animal testing and alternatives
- Advancements in Transdermal Drug Delivery
- Effects and risks of endocrine disrupting chemicals
Cosmetics are products used over long periods by the public, and their safety is very important. Several types of human tests widely for evaluation cosmetics including single patch tests, in-use repeated insult test (HRIPT). However, there no clear well-defined published objective standardized criteria primary skin irritation in regard to large variety cosmetic products.This study analysed conducted from May 2001 December 2012 with 4606 materials prototype or finished on 7440 normal Korean...
Despite the invention of various non-invasive bioengineering tools, skin-type analysis has largely been based on subjective assessments. However, advancements in functional cosmetic industry and artificial intelligence-assisted dermatology are creating a greater demand for an objective classification system.To propose system solely non-invasive, devices; provide reference values applicable to Korean population; compare our with those published studies.Biophysical parameter measurements were...
인체피부에서 화장품이나 화장품 원료의 안전성시험은 대체로 육안평가로 이루어져왔다. 하지만, 피부반응 초기의 미세한 변화에 대해서 육안으로는 감지하지 못하는 경우가 많다. 따라서, 본 연구에서는 수종의 원료에 의해 유발되는 홍반반응에 대해 육안평가뿐 아니라, 레이저도플러혈류이미지(LDPI) 측정장비를 이용한 혈류변화 측정, <TEX>$Vapometer^{(R)}$</TEX>를 경피수분손실량(TEWL) 분광광도계를 피부색 측정과 같은 기기평가를 병행하여 비교하였다. 30명의 건강한 여성 피험자를 대상으로 오일류 7종, 계면활성제류 6종, 보습제류 5종을 피험자의 등 부위에24 h 폐쇄첩포(D0)하여 피부반응을 유도하였고 첩포 제거 후 30 min (D1), 24 (D2)에 육안평가와 각각 실시하였다. 육안평가 결과, 프로필렌글라이콜을 제외한 모든 오일류와 보습제류는 저자극 수준의 피부반응(반응도 0+ - 2.9+)을 보인 반면, 프로필렌글라이콜과 계면활성제류는 중자극에서 강자극...
Abstract Findings obtained on objective assessments to evaluate sensitive skin do not correlate well with the symptomatology. We utilized reflectance confocal microscopy (RCM) compare transepidermal application of zinc in and non-sensitive skin. Thirty-six subjects participated this study. They were divided into groups based lactic acid sting test (LAST):‘stinger’ ‘non-stinger’; water loss (TEWL) measurements; sensitivity self-assessments: ‘sensitive’ ‘non-sensitive’. RCM images taken...