A5102735211- Neurogenesis and neuroplasticity mechanisms
- Physiological and biochemical adaptations
- Histone Deacetylase Inhibitors Research
- 14-3-3 protein interactions
- Nitric Oxide and Endothelin Effects
- Cancer-related cognitive impairment studies
- Chemical synthesis and alkaloids
- Animal Nutrition and Physiology
- Axon Guidance and Neuronal Signaling
- Cardiac Fibrosis and Remodeling
- Muscle Physiology and Disorders
- Magnetic and Electromagnetic Effects
- Cardiac Ischemia and Reperfusion
- Selenium in Biological Systems
- Adipose Tissue and Metabolism
- Meat and Animal Product Quality
- Trace Elements in Health
- GDF15 and Related Biomarkers
- Cell death mechanisms and regulation
- thermodynamics and calorimetric analyses
Huaihua University
2023-2024
Huazhong Agricultural University
2012-2016
Galanthamine, an alkaloid from the Amaryllidaceae family, serves as inhibitor of acetylcholinesterase. Beause its central cholinergic properties, galanthamine is currently being researched a potential therapeutic agent for treatment Alzheimer's disease. Nevertheless, full extent other biological activities still unclear. Here, we investigated in inducing neuronal differentiation and enhancing neurite outgrowth neural stem progenitor cells (NSPCs). Our comprehensive analysis revealed...
Chronic enteritis can produce an excess of reactive oxygen species resulting in cellular damage. Stanniocalcin-1(STC-1) reportedly possesses anti-oxidative activity, the aim this study was to define more clearly direct contribution STC-1 stress cattle. In study, primary intestinal epithelial cells (IECs) were exposed hydrogen peroxide (H2O2) for different time intervals mimic chronic enteritis-induced Prior treatment with 200 µM H2O2, transfected a recombinant plasmid 48 h over-express...
Stanniocalcin-1 (STC1) is a calcium and phosphate regulatory hormone. However, the exact molecular mechanisms underlying how STC1 affects Ca(2+) uptake remain unclear. Here, expression levels of transport proteins involved in transcellular Caco2 cells were examined following over-expression or inhibition STC1. These include transient receptor potential vanilloid members (TRPV) 5 6, plasma membrane ATPase 1b (PMCA1b), sodium/calcium exchanger (NCX1), vitamin D (VDR). Both gene protein...
Apoptosis repressor with caspase recruitment domain (ARC) is highly involved in apoptosis induced by oxidative stress or ischaemia/reperfusion injury. Furthermore, even though the exact mechanism still unknown, some studies suggest that exogenous ARC also possesses anti-apoptotic ability. The study investigated whether mouse-derived acquires ability and pathway of regulation chick embryo cardiomyocytes. To evaluate can inhibit cardiomyocyte hydrogen peroxide, recombinant pcDNA3.1/ARC plasmid...
Adult neurogenesis involves generation of functional neurons from neural progenitor cells, which have the potential to complement and restore damaged circuits. Therefore, development drugs that stimulate represents a promising strategy in stem cell therapy regeneration, greatly facilitating reconstruction circuits cases neurodegeneration brain injury. Our study reveals compound A5, previously designed synthesized by our team, exhibits remarkable neuritogenic activities, effectively inducing...
Neurogenesis in the adult brain comprises entire set of events neuronal development. It begins with division precursor cells to form a mature, integrated, and functioning network. Adult neurogenesis is believed play an important role animals' cognitive abilities, including learning memory. In present study, significant differentiation-promoting activity 80% (v/v) ethanol extract P. cocos (EEPC) was found Neuro-2a mouse cortical neural stem/progenitor (NSPCs). Subsequently, total 97 compounds...
Adult neurogenesis involves the generation of functional neurons from neural progenitor cells, which have potential to complement and restore damaged circuits. Therefore, development drugs that stimulate represents a promising strategy in stem cell therapy regeneration, greatly facilitating reconstruction circuits cases neurodegeneration brain injury. Our study reveals compound A5, previously designed synthesized by our team, exhibits remarkable neuritogenic activities, effectively inducing...