Experimental studies of charge injection and transport holes electrons in LUMATION™ Green 1300 Series light-emitting polymer (LEP) by a combination experimental techniques are reported. It is found that hole mobility lower than electron the former exhibits steeper electric-field dependence thus reducing misbalance between mobilities at higher device operating voltages. An approach to quantitatively analyze trapping organic semiconductors proposed. Based on our analysis, current limited from...

Chromosomal evolution in carnivores has been revisited extensively using cross-species chromosome painting. Painting probes derived from flow-sorted chromosomes of the domestic dog, which one most rearranged karyotypes mammals and highest dipoid number (2n=78) carnivores, are a powerful tool detecting both evolutionary intra- inter-chromosomal rearrangements. However, only few comparative maps have established between dog other non-Canidae species. Here, we extended painting with to seven...

The Zhenjiang section of the Grand Canal (ZGC) is an important part Canal, which was listed on World Heritage List in 2014. purpose this study to analyze projected image ZGC constructed by destination marketing organizations (DMO) WeChat official account (WOA) using network content analysis method condense features Internet and provide support for brand construction from supply side. results show that: (1) DMO pay more attention shipping traffic generate less publicity regarding literature...

The Vespertilionidae is the largest family in order Chiroptera and has a worldwide distribution temperate tropical regions. In to further clarify karyotype relationships at lower taxonomic level Vespertilionidae, genome-wide comparative maps have been constructed between <i>Myotis myotis</i> (MMY, 2n = 44) six vesper bats from China: altarium</i> (MAL, 44), <i>Hypsugo pulveratus</i> (HPU, 44),<i> Nyctalus velutinus</i> (NVE, 36),<i>...

Objective: We studied the changes in driving fatigue levels of experienced and inexperienced drivers at 3 periods day: 9:00 a.m.–12:00 p.m., 12:00 p.m.–2:00 4:00 p.m.–6:00 p.m.Methods: Thirty were involved 120-min real-car driving, sleepiness ratings (Stanford Sleepiness Scale, SSS; Hoddes et al. 1973 E, Zarcone V, Smythe H, Phillips R, Dement WC. Quantification sleepiness: a new approach. Psychophysiology. 1973;10:431–436.[Crossref], [PubMed], [Web Science ®] , [Google Scholar]),...

Cross-species chromosome painting has made a great contribution to our understanding of the evolution karyotypes and genome organizations mammals. Several recent papers comparative between tree flying squirrels have shed some light on family Sciuridae order Rodentia. In present study we extended Himalayan marmot <i>(Marmota</i><i>himalayana)</i> African ground squirrel <i>(Xerus cf. erythropus)</i>, i.e. representative species from another important group...

Purpose Wayfinding efficiency is an extremely influential factor to improve users' library interior experience. However, few research has studied the different functions of various wayfinding signages for university users through mobile visual experiment. To fill this gap, purpose paper explore relationship between signage system design and patrons' behavior features. Design/methodology/approach In article, eye movement tracking method was introduced record data during process participants...

We investigated the role of promoter methylation transcriptional and inflammatory factors, including TBX21, GATA3, RORγt, FOXP3, IFN-γ, IL-4, IL-17A, TGF-β in development Vogt-Koyanagi-Harada (VKH) disease.The levels were detected by Sequenom MassARRAY system CD4+ T cells that separated from 20 healthy individuals 32 VKH patients (20 active stage without medication, 12 inactive with medication). The mRNA expression level was analyzed real-time RT-PCR.The significantly higher than (P < 0.05)....

Previous studies show that endoplasmic reticulum-associated aminopeptidase (ERAP1/ERAP2) and runt-related transcription factor 3 (RUNX3) gene polymorphisms are associated with AS (ankylosing spondylitis) in European Caucasians. However, contradictory results were reported different Asian populations. The purpose of this study was to determine whether eleven candidate single nucleotide (SNPs) ERAP1/ERAP2 six RUNX3 genes confer susceptibility or without acute anterior uveitis (AAU) [AS+ AAU+...

Considering the giraffe (Giraffa camelopardalis, GCA, 2n = 30) as a primitive species, its comparative genomic data are critical for our understanding of karyotype evolution pecorans. Here, we have established genome-wide chromosomal homologies between giraffe, Chinese muntjac (Muntiacus reevesi, MRE, 46) and human (Homo sapiens, HSA, with whole sets chromosome-specific paints from human, in addition to providing high-resolution G-banding giraffe. chromosome detected 32 45 autosomal homologs...

// Yunyun Zhu 1 , Yiguo Qiu Hongsong Yu Shenglan Yi Wencheng Su Aize Kijlstra 2 and Peizeng Yang The First Affiliated Hospital of Chongqing Medical University, Key Laboratory Ophthalmology Eye Institute, Chongqing, China University Clinic Maastricht, Netherlands Correspondence to: Yang, email: peizengycmu@126.com Keywords: DNA methylation, Behcet&rsquo;s disease, CD4 + T cell Received: May 19, 2017&emsp;&emsp;&emsp;&emsp; Accepted: June 12, Published: July 22, 2017 ABSTRACT pathogenesis...

Aberrant methylation change of IRF8 confers risk to various tumors, and abnormal expression is involved in many autoimmune diseases, including ocular Behcet's disease. However, whether the associated with Vogt-Koyanagi-Harada (VKH) disease remains unknown. In present study, we found a decreased mRNA association higher level monocyte-derived dendritic cells (DCs) from active VKH patients compared normal inactive subjects. DCs incubated cyclosporin (CsA) or dexamethasone (DEX) showed lower...

There has been an increase in demand for research data management (RDM) policies to improve the quality of however, there is no clear-cut policy content guide process. The purpose this study identify existing RDM policies. Specifically, compares and differentiates three developed nations (USA, UK Australia) ascertain how vary. 100 universities from countries, that are present online were retrieved analysis approach using NVivo SPSS performed. results revealed common underlying facts found...

We have investigated the karyotype relationships of two oriental voles, i.e. Yulong vole (&lt;i&gt;Eothenomys proditor, &lt;/i&gt;2n = 32) and large miletus, 56) as well Clarke’s (&lt;i&gt;Microtus clarkei, 52), by a combined approach cross-species chromosome painting high-resolution G-banding comparison. Chromosome-specific probes were generated from flow-sorted chromosomes &lt;i&gt;E. proditor&lt;/i&gt; hybridized onto metaphases proditor&lt;/i&gt;, miletus &lt;/i&gt;and &lt;i&gt;M....

Xenarthra, as the probable earliest offshoot of placental tree, represents a key taxon for understanding mammalian phylogeny. To gain further insight into chromosomal evolution and genome organization xenarthrans, we have established first genome-wide comparative chromosome map between human 6-banded armadillo (&lt;i&gt;Euphractus&lt;/i&gt;&lt;i&gt;sexcinctus&lt;/i&gt;, 2n = 58), basal species on Xenarthra branch, by reciprocal cross-species painting. In total, 22 autosomal paints revealed...

Glucagon-like peptide-1 (GLP-1) is an incretin (a type of metabolic hormone that stimulates a decrease in blood glucose levels), holding great potential for the treatment 2 diabetes mellitus (T2DM). However, its extremely short half-life 1–2 min hampers any direct clinical application. Here, we describe application heavy chain human ferritin (HFt) nanocage as carrier to improve pharmacological properties GLP-1. The GLP-HFt was designed by genetic fusion GLP-1 N-terminus HFt and expressed...

Aberrant methylation of interferon regulatory factor 8 (IRF8) has been noted in various tumors. IRF8 also reported to be involved many autoimmune diseases, including Behcet's disease (BD). However, the status BD not reported. To address this issue, we investigated whether degree dendritic cells (DCs) plays a role development BD. We found lower mRNA expression and higher level active ocular patients as compared normal subjects inactive patients. Treatment with demethylation agent,...