A5004340170- Pancreatic and Hepatic Oncology Research
- Synthesis and Catalytic Reactions
- Chemical Synthesis and Reactions
- Gallbladder and Bile Duct Disorders
- Asymmetric Synthesis and Catalysis
- Surgical Simulation and Training
- Synthetic Organic Chemistry Methods
- Enzyme Catalysis and Immobilization
- Sulfur-Based Synthesis Techniques
- Cancer Genomics and Diagnostics
- Colorectal Cancer Surgical Treatments
- Vanadium and Halogenation Chemistry
- Cancer Immunotherapy and Biomarkers
- Renal and related cancers
- Colorectal Cancer Screening and Detection
- Advanced Synthetic Organic Chemistry
- Catalysis for Biomass Conversion
- Synthesis and biological activity
- Pediatric Hepatobiliary Diseases and Treatments
- Catalytic C–H Functionalization Methods
- Cyclopropane Reaction Mechanisms
- Multicomponent Synthesis of Heterocycles
- Lipid metabolism and biosynthesis
- Synthesis of heterocyclic compounds
- Minimally Invasive Surgical Techniques
Sichuan University
2005-2025
Sichuan Cancer Hospital
2024
West China Hospital of Sichuan University
2020-2024
Temple University
2023-2024
Nanjing Tech University
2024
First Affiliated Hospital of Xi'an Jiaotong University
2023
Dalian Polytechnic University
2020-2022
Third Xiangya Hospital
2022
Central South University
2004-2022
Zhejiang University of Technology
2017-2020
Abstract Background Intraductal papillary mucinous neoplasms (IPMN) often coexist with acute or chronic pancreatitis, which can complicate laparoscopic spleen-preserving distal pancreatectomy (LSPDP), especially splenic vessel preservation (SVP-LSPDP). This study aims to evaluate the safety, feasibility, and long-term outcomes of SVP-LSPDP for IPMN. Methods A retrospective was conducted on IPMN patients who underwent between November 2017 December 2022. Demographics, surgical outcomes,...
Abstract A simple protocol for the synthesis of 2‐(trifluoromethyl)aniline derivatives through a coordinating activation strategy was developed. The reaction showed good reactivity and gave target products in moderate to yields. Pleasingly, directing group could be recovered excellent yield. Furthermore, this allowed efficient access floctafenine. single‐electron‐transfer mechanism proposed responsible trifluoromethylation reaction.
Abstract A practical method has been developed for the C ‐sulfinylation of enamides and enecarbamates using sodium phenylsulfinate/methyltrichlorosilane (PhSO 2 Na/MeSiCl 3 ) as sulfinylating reagent N , ‐dimethylacetamide (DMAc) Lewis base promoter, which allows preparation a variety ‐protected‐β‐sulfinylenamines in high yields good stereoselectivities. The is found to be important both situ generation active species (PhSOCl) sulfinylation step.
Abstract The first palladium‐catalyzed direct benzylic C( sp 3 )−H chalcogenation with diaryl disulfides and diphenyl diselenide has been established. coupling reaction proceeds between the thioether radical palladiumcycle intermediate. Picolinamide serves as an excellent directing group for C−H activation of can be easily removed. current protocol exhibits a relatively broad substrate scope high functional compatibility. A mechanistic study indicates that palladium(IV) intermediate is...
Catalytic production of structured phospholipids (SPLs) containing short-chain fatty acids (SCFAs) in an efficient heterogeneous manner is great importance from the standpoint food engineering. Herein, a bifunctionalized sulfonated Zn-SBA-15 catalyst was studied for SPL synthesis through interesterification soybean lecithin with ethyl propionate or methyl butyrate. Various characterization techniques such as pyridine Fourier transform infrared spectroscopy, X-ray photoelectron and...
Abstract Pulmonary embolism (PE) is the third leading cause of cardiovascular death in United States. Black Americans have higher incidence, greater clot severity, and worse outcomes than White Americans. This disparity not fully understood, especially context advent PE response teams (PERT), which aim to standardize PE‐related care. retrospective single‐center cohort study compared 294 131 patients from our institution's PERT database. Primary objectives included severity in‐hospital...
Abstract Intra-abdominal adhesions have consistently posed a challenge for surgeons during procedures. This study aims to investigate the feasibility of utilizing indocyanine green (ICG) in conjunction with near-infrared imaging detection intra-abdominal adhesions. In vitro, we analyzed factors affecting ICG fluorescence. We divided SD rats into groups excretion different digestive tract regions. Additionally, reviewed surgical videos from previous cholecystectomy cases, categorizing them by...
Succinate dehydrogenase subunit B (SDHB)-mutated paragangliomas (PGLs) are rare neuroendocrine tumors characterized by increased malignancy, readily metastasizing, and poorer prognosis. Here we report a case of SDHB-mutated metastatic PGL, wherein the patient showed significant tumor shrinkage complete symptom remission following chemotherapy. We aim to contribute additional evidence existing knowledge associated with PGLs.
Abstract Easily accessible chiral phosphoric acid 1b has been applied as efficient organocatalyst for the asymmetric allylation of aldehydes with allyltrichlorosilane. In presence 20 mol% , a broad range proceeded smoothly to give corresponding homoallylic alcohol up 87% ee and 97% yield.
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Dichromate Oxidation of GlycolsK. L. ChengCite this: Anal. Chem. 1961, 33, 6, 781–782Publication Date (Print):May 1, 1961Publication History Published online1 May 2002Published inissue 1 1961https://pubs.acs.org/doi/10.1021/ac60174a036https://doi.org/10.1021/ac60174a036research-articleACS PublicationsRequest reuse permissionsArticle Views66Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum full text article...
Efficient and sustainable production of structured phospholipids (SPLs) enriched in medium-chain fatty acids (MCFAs) a heterogeneous manner is crucial for their potential applications functional foods drugs. Herein, the first time, Zn- Al-incorporated SBA-15 silicas were prepared by coprecipitation method further researched catalytic synthesis MCFA-enriched SPLs through acidolysis reaction natural with capric or caprylic acid.The as-prepared samples exhibited superior activities under mild...
Abstract There is a significant difference in prognosis and response to chemotherapy between basal classical subtypes of pancreatic ductal adenocarcinoma (PDAC). Further biomarkers are required identify PDAC. We selected candidate via review articles. Correlations these markers the PDAC molecular subtype gene sets were analyzed using bioinformatics, confirming for identifying subtypes. Subsequently, 298 patients included, their tumor tissues immunohistochemically stratified biomarkers....
Currently, safety of laparoscopic pancreaticoduodenectomy (LPD) in patients with liver cirrhosis is unknown. The aim this study was to explore postoperative morbidity and mortality long-term outcomes cirrhotic after LPD. a one-center retrospective comprising 353 who underwent LPD between October 2010 December 2019. A total 28 had were paired 56 non-cirrhotic counterparts through propensity score matching (PSM). Baseline data, intra-operative survival data collected. Postoperative considered...
Abstract Intraductal papillary mucinous neoplasms (IPMN) is one of the known precancerous lesions. Patients’ prognosis aggravated as IPMN transforms into invasive Pancreatic Ductal Adenocarcinoma (PDAC). The molecular mechanisms underlying this progression lack effective experimental models and urgently need to be elaborated. We performed spatial transcriptomics (ST) on fresh tissue samples from same patient including normal pancreas, high-grade IPMN, PDAC, described step-by-step development...
Iatrogenic bile duct injuries (BDIs) prevention during laparoscopic cholecystectomy (LC) relies on meticulous anatomical dissections through direct visualization. Near-infrared fluorescence (NIRF) with indocyanine green (ICG) improves the visualization of extrahepatic biliary structures. Although ICG can be administered either intravenously or intragallbladder, there remains uncertainty regarding optimal method for different patient populations. This study sought to assess suitability each...