A5009831579- Pancreatic and Hepatic Oncology Research
- Gallbladder and Bile Duct Disorders
- Bone Tissue Engineering Materials
- Dental Implant Techniques and Outcomes
- Graphene and Nanomaterials Applications
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gastric Cancer Management and Outcomes
- Dental Radiography and Imaging
- Dental Research and COVID-19
- Colorectal Cancer Screening and Detection
- Pancreatitis Pathology and Treatment
- Pediatric Hepatobiliary Diseases and Treatments
- Oral microbiology and periodontitis research
- Dental materials and restorations
- Nanoparticle-Based Drug Delivery
- RNA Interference and Gene Delivery
- Rheumatoid Arthritis Research and Therapies
- Reproductive System and Pregnancy
- Outsourcing and Supply Chain Management
- Immune Response and Inflammation
- ERP Systems Implementation and Impact
- Ovarian function and disorders
- Osteoarthritis Treatment and Mechanisms
- Periodontal Regeneration and Treatments
- Nanoplatforms for cancer theranostics
Sichuan University
2016-2025
Northwest Women's and Children's Hospital
2024
West China Hospital of Sichuan University
2016-2024
State Key Laboratory of Oral Diseases
2016-2024
State Key Laboratory of Biotherapy
2019-2024
Nuffield Orthopaedic Centre
2020
University of Oxford
2020
National Clinical Research
2020
Stomatology Hospital
2020
Versus Arthritis
2020
Abstract As a new class of crystalline nanoporous materials, metal‐organic frameworks (MOFs) have recently been used for biomedical applications due to their large surface area, high porosity, and theoretically infinite structures. To improve the biological performance titanium, MOF films were applied modification titanium. Zn‐based composed zeolitic imidazolate framework‐8 (ZIF‐8) crystals with nanoscale microscale sizes (nanoZIF‐8 microZIF‐8) prepared on porous titanium surfaces by...
A nanoZIF-8 modified porous composite scaffold was fabricated <italic>via</italic> extrusion-based 3D printing technology, which could promote osteogenesis <italic>in vitro</italic> and accelerate bone regeneration vivo</italic>.
Abstract Mesenchymal stem cell (MSC)-mediated immunomodulation has been harnessed for the treatment of human diseases, but its underlying mechanism not fully understood. Dead cells, including apoptotic cells have immunomodulatory properties. It repeatedly reported that proportion nonviable MSCs in a MSC therapeutic preparation varied from 5~50% ongoing clinical trials. is conceivable may play role effects MSCs. We found present study had about 5% dead (DMSCs), characterized by cells. Namely,...
Toll-like receptor (TLR) agonists as the potent stimulants of an innate immune system hold promises for applications in anticancer immunotherapy. However, most them are limited clinical translation due to uncontrolled systemic inflammatory response. In current study, 1V209, a small molecule TLR7 agonist, was conjugated with cholesterol (1V209-Cho) and prepared into liposomes (1V209-Cho-Lip). 1V209-Cho-Lip exerted minimal toxic effects enhanced transportation ability lymph nodes (LNs)...
Abstract Background Intraductal papillary mucinous neoplasms (IPMN) often coexist with acute or chronic pancreatitis, which can complicate laparoscopic spleen-preserving distal pancreatectomy (LSPDP), especially splenic vessel preservation (SVP-LSPDP). This study aims to evaluate the safety, feasibility, and long-term outcomes of SVP-LSPDP for IPMN. Methods A retrospective was conducted on IPMN patients who underwent between November 2017 December 2022. Demographics, surgical outcomes,...
Abstract Background Sport participants are at increased risk of joint pain and osteoarthritis. A better understanding factors associated with osteoarthritis in this population could inform the development strategies to optimise their long-term health. The purpose study was describe prevalence former cricketers, determine whether playing position, standard (i.e. elite or recreational standard) length-of-play region-specific pain. Methods data were from Cricket Health Wellbeing Study (CHWS), a...
In the present study, a cell-penetrating peptide, transactivating transcriptional factor (TAT) domain from HIV, was linked to PEGylated multi-walled carbon nanotubes (MWCNTs) develop highly effective antitumor drug delivery system. FITC conjugated on MWCNTs-polyethylene glycol (PEG) and MWCNTs-PEG-TAT provide fluorescence signal for tracing cellular uptake of nanocarrier. After loaded with an anticancer agent, doxorubicin (DOX) via π - stacking interaction, physicochemical characteristics,...
Achieving textbook outcome (TO) implies a smooth recovery post-operation without specified composite complications. This study aimed to evaluate TO in laparoscopic pancreaticoduodenectomy (LPD) and identify independent risk factors associated with achieving TO. We conducted retrospective analysis of data from randomized controlled trial on LPD at West China Hospital (ChiCTR1900026653). Patients were categorized into the non-TO groups. Perioperative variables compared between these...