A5102920531- Glioma Diagnosis and Treatment
- Extracellular vesicles in disease
- Stochastic Gradient Optimization Techniques
- Neuroblastoma Research and Treatments
- Brain Metastases and Treatment
- Bone Tissue Engineering Materials
- Meningioma and schwannoma management
- Radiomics and Machine Learning in Medical Imaging
- Domain Adaptation and Few-Shot Learning
- Advanced Neural Network Applications
- Power Systems and Renewable Energy
- Geodetic Measurements and Engineering Structures
- Simulation and Modeling Applications
- Evaluation and Optimization Models
- Advanced Image Processing Techniques
- Medical Imaging Techniques and Applications
- Nanoplatforms for cancer theranostics
- Industrial Technology and Control Systems
- Advanced Surface Polishing Techniques
- Sparse and Compressive Sensing Techniques
- Plasma Applications and Diagnostics
- Machine Learning and ELM
- Advanced Algorithms and Applications
- RNA Interference and Gene Delivery
- 3D Printing in Biomedical Research
Peking Union Medical College Hospital
2021-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2021-2025
Xi'an Jiaotong University
2024-2025
Sichuan University
2010-2025
Soochow University
2024
Kunming Medical University
2022
State Key Laboratory of Oral Diseases
2022
Hunan Agricultural University
2020-2022
First Affiliated Hospital of Kunming Medical University
2022
Yangzhou University
2021
Abstract Background The coronavirus disease 2019 (COVID-19) has been a pandemic worldwide. Old age and underlying illnesses are associated with poor prognosis among COVID-19 patients. However, whether frailty, common geriatric syndrome of reduced reserve to stressors, is older patients unknown. aim our study investigate the association between frailty severe aged ≥ 60 years. Methods A prospective cohort 114 hospitalized (≥ years) confirmed pneumonia was conducted 7 February 2020 6 April...
Background The 5th edition of the World Health Organization (WHO) classification central nervous system tumors incorporated specific molecular alterations into categorization gliomas. major revision scheme effectuates significant changes in diagnosis and management glioma. This study aimed to depict clinical, molecular, prognostic characteristics glioma its subtypes according current WHO classification. Methods Patients who underwent surgery for at Peking Union Medical College Hospital...
Background The 2021 World Health Organization Classification of Central Nervous System Tumors updates glioma subtyping and grading system, incorporates EGFR amplification (Amp) as one diagnostic markers for glioblastoma (GBM). Purpose This study aimed to describe the frequency, clinical value molecular correlation Amp in diffuse gliomas based on latest classification. Methods We reviewed patients between 2011 2022 at our hospital, included 187 adult with available tumor tissue detection...
The 2021 WHO Classification of Central Nervous System Tumors introduces more molecular markers for glioma reclassification, including TERT promoter (TERTp) mutation as a key feature in glioblastoma diagnosis. Given the changes entities included each subtype under new classification, this research investigated distribution, prognostic value, and correlations with other alterations TERTp different subgroups latest classification. All patients admitted to Peking Union Medical College Hospital...
ABSTRACT This study investigates the bidirectional effects of plasma‐activated water (PAW) on Botrytis cinerea . At low PAW concentrations, fungal growth was promoted, with spore multiplication reaching 54.46 ± 7.16% (PAW‐10) and mycelial at 4.88 1.83% (PAW‐2). However, higher effect shifted to inhibition, inactivation 41.99 8.58% (PAW‐30) 7.30 1.73% (PAW‐30). Critical thresholds for promotion inhibition were observed PAW‐18 PAW‐5, respectively. H 2 O + in promoted reproduction...
Structured pruning is a commonly used technique in deploying deep neural networks (DNNs) onto resource-constrained devices. However, the existing methods are usually heuristic, task-specified, and require an extra fine-tuning procedure. To overcome these limitations, we propose framework that compresses DNNs into slimmer architectures with competitive performances significant FLOPs reductions by Only-Train-Once (OTO). OTO contains two keys: (i) partition parameters of zero-invariant groups,...
The latest fifth edition of the World Health Organization (WHO) classification central nervous system (CNS) tumors (WHO CNS 5 classification) released in 2021 defined astrocytoma, IDH-mutant, Grade 4. However, understanding this subtype is still limited. We conducted study to describe features 4 and explored similarities differences between histological molecular subtypes.Patients who underwent surgery from January 2011 2022, classified as were included study. Clinical, radiological,...
In order to investigate the mechanism of interaction between a vertical rotary tiller and soil obtain best structural operational parameters tool, improve quality tiller, achieve effect breaking leveling meet agronomic requirements tillage, series simulation tests was conducted through design 3D models tillers with different forms building discrete element action soil. The virtual operating carried out by EDEM, effects parameters, tool bending angle, cutter installation number on were...
Magnesium transporter subtype 1 (MAGT1) is known to participate in animal development and cell differentiation. Thus far, MAGT1 studies have mainly focused on its role cardiomyocyte regulation differentiation; only a few demonstrated proliferation. To investigate the underlying mechanism of proliferation, HeLa SiHa cells were transiently knocked down with different siRNAs. We showed that proliferation was substantially restricted by S-phase arrest apoptosis MAGT1-knocked cells, which further...
To evaluate the value of shear wave elastography (SWE) in avoiding repeat fine-needle aspiration thyroid nodules with nondiagnostic and undetermined cytology.A total 232 (n = 132) 100) cytology underwent ultrasound (US) SWE, followed by (US)-guided (FNAC). The final diagnosis was based on cytological or pathological findings. US SWE characteristics benign malignant were compared using χ2 -test. receiver operating characteristic (ROC) curves imaging reporting data system (TI-RADS) categories...
Abstract Background Intratumoral hemorrhage, though less common, could be the first clinical manifestation of glioma and is detectable via MRI; however, its exact impacts on patient outcomes remain unclear controversial. The 2021 WHO CNS 5 classification emphasised genetic molecular features, initiating necessity to establish correlation between hemorrhage alterations. This study aims determine prevalence intratumoral in subtypes identify associated characteristics improve management....
Chemiluminescence (CL) is of great significance in biochemical analysis and imaging due to its high sensitivity lack need for external excitation. In this review, we summarized the recent progress AIE-based CL systems, including their working mechanisms applications analysis, bioimaging, disease diagnosis treatment. ion molecular detection, shows selectivity sensitivity, especially detection dynamic reactive oxygen species (ROS). Further, integrated NIR-CL single-molecule system...
Abstract Glioblastoma accounts for almost half of all intracranial primary malignancies and has the worst prognosis. Because its high malignancy frequent recurrence after standard therapy, it is great significance to explore new therapy options. Recently immune taken remarkable progress in a variety tumors, among which peptide vaccines utilize sequences based on tumor-specific antigens or tumor-associated antigen targets activate self-immune response against tumor cells. However, due...