A5040770764- Lymphoma Diagnosis and Treatment
- Viral-associated cancers and disorders
- Cancer Immunotherapy and Biomarkers
- Parvovirus B19 Infection Studies
- Polyomavirus and related diseases
- Multiple Myeloma Research and Treatments
- Spanish Literature and Culture Studies
- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Cytomegalovirus and herpesvirus research
- Medical and Biological Sciences
- Health Policy Implementation Science
- Chronic Lymphocytic Leukemia Research
- Healthcare Systems and Public Health
- Cancer Diagnosis and Treatment
- Health and Lifestyle Studies
- Hematological disorders and diagnostics
- Literature, Culture, and Aesthetics
- T-cell and Retrovirus Studies
- Lung Cancer Treatments and Mutations
- Multiple Sclerosis Research Studies
- Celiac Disease Research and Management
- Latin American Literature Analysis
- Cancer-related molecular mechanisms research
- Herpesvirus Infections and Treatments
University of Southern California
2013-2024
Abstract Classic Hodgkin Lymphoma (CHL) is a B-cell lymphoma characterized by Reed- Sternberg (HRS) cells surrounded immune cell infiltrates that define histological subtypes. A subset of CHL tumors shows integration the Epstein-Barr virus (EBV) genome into HRS cell. EBV tumor positivity thought to reflect immunocompromised status and has been more common in young older patients, non-white patients lower socioeconomic status. This study aims examine distribution prevalence determine whether...
Abstract This abstract is being presented as a short talk in the scientific program. A full printed Proffered Abstracts section (PR008) of Conference Program/Proceedings. Citation Format: Lenora WM Loo, Yuquing Li, Kami K. White, Jose A. Aparicio, Veronica W. Setiawan, Christopher Haiman, Anna H. Wu, Lynne R. Wilkens, Loic Le Marchand, Brenda Y Hernandez, Iona Cheng. Racial and Ethnic Differences Biological Signatures Breast Tumors Immune-microenvironment: The Multiethnic Cohort Study...
Abstract Lung cancer remains the leading cause of cancer-related mortality globally and continues to contribute significantly health disparities. Black/African American (B/AA) men exhibit a higher risk lung compared White men; B/AA individuals also lower 5-year survival stage-specific rates than subjects. Biological factors, including genetic differences in driver mutation, may influence this disparity. adenocarcinoma (LUAD) is most common histological subtype across all ethnic groups,...
Abstract Background: In the U.S., there are stark racial and ethnic differences in incidence mortality of breast cancer that cannot be fully explained by lifestyle environmental factors. The contribution tumor biology to these outcomes across race ethnicity is poorly understood. We conducted a preliminary analysis gene expression profiles biological signatures tumors within Multiethnic Cohort Study (MEC). Methods: For 279 postmenopausal females with invasive MEC, we examined 42 based on...
Background: Previous studies have estimated 2-10% of all cases multiple sclerosis (MS) to be childhood onset. How pediatric MS compares adults in Hispanic Americans is less known. Objective: To characterize Hispanics with onset and compare them adult-onset MS. Methods: A cross-sectional study 348 patients followed at University Southern California Medical Center, including Children's Hospital Los Angeles, complete clinical information; age symptoms diagnosis assessed by medical chart...
OBJECTIVE: To compare US born (US or migrant age < 15 years) Hispanics and non-US (migrant 蠅15 with MS, determine whether timing of migration influences disability in MS. BACKGROUND: the multiple sclerosis (MS) represent a less studied population. are diverse community where their source health information knowledge about MS may depend on level acculturation. Time spent can serve as proxy to acculturation elucidate social behavioral factors that could be important disability. METHODS:...
Abstract Epstein-Barr virus (EBV) is present in a varying proportion of classical Hodgkin lymphoma (cHL) tumors reportedly associated with age, sex, race/ethnicity and histologic subtype. As part study to examine the tumor microenvironment survival multiethnic set US cHL cases, we examined distribution EBV expression blocks from subset 269 available cases. We confirmed diagnosis histological subtype H&E sections FFPE excisions core biopsies cases provided by Southern California Kaiser,...
Abstract Background Classical Hodgkin lymphoma (cHL) is one of the most common cancers among adolescents and young adults (AYA). Incidence rates vary by demographic factors, with highest incidence in whites high SES. Malignant Reed-Sternberg (HRS) cells comprise a small percentage tumor (about 1%), remainder composed various immune (tumor microenvironment, TME). The TME cHL predicts survival response to treatment NHW, but has not been examined diverse populations. We implemented study...