A5067993480- Bladder and Urothelial Cancer Treatments
- Renal cell carcinoma treatment
- Prostate Cancer Diagnosis and Treatment
- Urological Disorders and Treatments
- Urinary Bladder and Prostate Research
- Radiomics and Machine Learning in Medical Imaging
- Renal and Vascular Pathologies
- Surgical Simulation and Training
- Pelvic floor disorders treatments
- Prostate Cancer Treatment and Research
- Urinary and Genital Oncology Studies
- Inflammatory Biomarkers in Disease Prognosis
- Colorectal Cancer Surgical Treatments
- Anatomy and Medical Technology
- Renal and related cancers
- Optical Imaging and Spectroscopy Techniques
- Advanced X-ray and CT Imaging
- Simulation-Based Education in Healthcare
- Cardiovascular Disease and Adiposity
- Minimally Invasive Surgical Techniques
- Electrolyte and hormonal disorders
- Urologic and reproductive health conditions
- Ureteral procedures and complications
- Organ Donation and Transplantation
- MRI in cancer diagnosis
University Medical Centre Mannheim
2020-2025
Heidelberg University
2020-2025
University Hospital Heidelberg
2020-2025
German Cancer Research Center
2024-2025
Universität Hamburg
2024
University Medical Center Hamburg-Eppendorf
2024
Martin Luther University Halle-Wittenberg
2024
University Hospital Carl Gustav Carus
2024
TU Dresden
2024
University Medical Center
2023-2024
Abstract Introduction Simulator training is an efficient method for the development of basic laparoscopic skills. We aimed to investigate if low-cost simulators are comparable more expensive box trainers regarding surgeons usability, likability, and performance. Methods This multi-center, randomized crossover study included 16 medical students, seven abdominal surgeons, urological surgeons. Participants performed four tasks (peg transfer, circle cutting, balloon resection, suture knot) on...
Accurate intraoperative assessment of organ perfusion is a pivotal determinant in preserving function e.g. during kidney surgery including partial nephrectomy or transplantation. Hyperspectral imaging (HSI) has great potential to objectively describe and quantify this as opposed conventional surrogate techniques such ultrasound flowmeter, indocyanine green the subjective eye surgeon. An established live porcine model under general anesthesia received median laparotomy renal mobilization....
Holmium laser enucleation of the prostate (HoLEP) is an established option in surgical treatment benign prostatic hyperplasia. Pulse modulation, such as MOSES® technology, has recently been introduced and may offer potential advantages HoLEP.
Before holmium laser enucleation of the prostate (HoLEP), many patients have undergone short-term biopsy (PB) to rule out presence cancer. The aim this study is determine whether a PB before HoLEP has an impact on perioperative outcomes or complications HoLEP.
To evaluate perioperative parameters, clinical outcomes, and the learning curve of holmium laser enucleation prostate (HoLEP) a single surgeon in 500 consecutive cases.
To assess the baseline inflammatory markers modified Glasgow Prognostic Score (mGPS), systemic immune-inflammation index (SII), and neutrophile-to-lymphocyte ratio (NLR) as pragmatic tools for predicting response to chemohormonal therapy (docetaxel plus ADT) prognosis in men with metastatic hormone-sensitive prostate cancer (mHSPC).Male patients who received docetaxel at a tertiary university care center between 2014 2019 were screened completion of 6 cycles. NLR, SII, mGPS, overall survival...
The purpose of this study was to evaluate the outcomes performing 2 consecutive open radical cystectomies (RCs) within 1 day by same surgical team. A retrospective analysis conducted on data from patients who underwent RC at a single tertiary care center January 2015 February 2023. Patient characteristics, perioperative and endpoints were analyzed. Univariable multivariable logistic regression models created predict major complications. total 657 included in final cohort, containing 64...
Background:Simulator training is an efficient tool to develop surgical novice's basic laparoscopic skills.Currently simulator takes mainly place in simulation centers at hospitals and universities.Additionally, most trainees have use overtime for purposes since it mostly not included during normal working hours.Recent studies also indicated the possibility of low cost at-home surgery, opening up new personalized possibilities.Such modalities support surgeons' initial acquisitions skills as...
Knowledge of current and ongoing studies is critical for identifying research gaps enabling evidence-based decisions individualized treatment. However, the increasing number scientific publications poses challenges healthcare providers patients in all medical fields to stay updated with latest evidence. To overcome these barriers, we aim develop a living systematic review open-access online evidence map surgical therapy bladder cancer (BC), including meta-analyses.Following guidelines...
To assess the predictive and prognostic value of changes in longitudinal neutrophile-to-lymphocyte (NLR) ratios men receiving taxane-based chemotherapy for metastatic prostate cancer (PC).Retrospective, unicentric cohort study patients treated with either docetaxel hormone-sensitive PC (mHSPC) or cabazitaxel castration-refractory (mCRPC) at a tertiary referral hospital between 2010 2019. NLR were calculated each cycle. Next, slopes over first three (NLR3) six cycles (NLR6) analysed...
Introduction Randomised controlled trials comparing robotic-assisted partial nephrectomy (RAPN) and open PN (OPN) are lacking. Therefore, we aim to report the study protocol a trial update for randomised feasibility RAPN versus OPN renal neoplasms. Methods analysis The ROBOtic assisted conventional Open Partial II is designed as single-centre, randomised, open-label, trial. Participation will be offered patients with neoplasms deemed feasible both, RAPN. We enrol 50 within 15 months using...
The aim of this study was to assess the value computed tomography (CT)-based radiomics perinephric fat (PNF) for prediction surgical complexity.Fifty-six patients who underwent renal tumor surgery were included. Radiomic features extracted from contrast-enhanced CT. Machine learning models using radiomic features, Mayo Adhesive Probability (MAP) score, and/or clinical variables (age, sex, and body mass index) compared adherent PNF (APF), occurrence postoperative complications (Clavien-Dindo...
Besides sepsis and malignancy, malperfusion is the third leading cause of tissue degradation a major pathomechanism for various medical surgical conditions. Despite significant developments such as bypass surgery, endovascular procedures, extracorporeal membrane oxygenation, artificial blood substitutes, malperfusion, especially visceral organs, remains pressing issue in patient care. The demand further research on biomedical processes possible interventions high. Valid biological models are...
Abstract Purpose Radical cystectomy is associated with bleeding and high transfusion rates, presenting challenges in patient management. This study investigated the prophylactic use of tranexamic acid during radical cystectomy. Methods All consecutive patients treated at a tertiary care university center were included from prospectively maintained database. After an institutional change protocol received 1 g intravenous bolus as prophylaxis. To prevent bias, propensity score matching was...
<b><i>Introduction:</i></b> To compare RENAL, preoperative aspects and dimensions used for an anatomical (PADUA) classification, Mayo Adhesive Probability (MAP) scores with the respective intraoperative findings surgeon’s assessment in predicting surgical outcome of patients undergoing partial nephrectomy. <b><i>Methods:</i></b> Data 150 eligible treated at University Medical Center Mannheim between 2016 2018 were analyzed. Tumors...