A5061749779- Intestinal and Peritoneal Adhesions
- Appendicitis Diagnosis and Management
- Esophageal and GI Pathology
- Biliary and Gastrointestinal Fistulas
- COVID-19 Clinical Research Studies
- Gallbladder and Bile Duct Disorders
- COVID-19 and healthcare impacts
- Gastrointestinal disorders and treatments
- Abdominal Trauma and Injuries
- Hernia repair and management
- Intestinal Malrotation and Obstruction Disorders
- Long-Term Effects of COVID-19
- Intraperitoneal and Appendiceal Malignancies
- Diverticular Disease and Complications
- Clinical Nutrition and Gastroenterology
- Trauma Management and Diagnosis
- Cutaneous lymphoproliferative disorders research
- Congenital Anomalies and Fetal Surgery
- SARS-CoV-2 and COVID-19 Research
- Colorectal Cancer Surgical Treatments
- Abdominal Surgery and Complications
- Surgical Sutures and Adhesives
- Gastric Cancer Management and Outcomes
- Nail Diseases and Treatments
- Pancreatic and Hepatic Oncology Research
Universität Hamburg
1983-2025
University Medical Center Hamburg-Eppendorf
2020-2025
University Hospital Carl Gustav Carus
2024
TU Dresden
2024
National Center for Tumor Diseases
2024
Marienkrankenhaus Hamburg
2021
Zimmer Biomet (United Kingdom)
2021
Seoul National University Hospital
2020
Vienna General Hospital
1994-1998
Allgemeines Krankenhaus Celle
1980-1996
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be documented in various tissues, but the frequency of cardiac involvement as well possible consequences are unknown.To evaluate presence SARS-CoV-2 myocardial tissue from autopsy cases and to document a response that infection.This cohort study used data consecutive Germany between April 8 18, 2020. All patients had tested positive for pharyngeal swab tests.Patients who died disease 2019.Incidence positivity CD3+, CD45+, CD68+...
Autopsies of deceased with a confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can provide important insights into the novel disease and its course. Furthermore, autopsies are essential for correct statistical recording 2019 (COVID-19) deaths. In northern German Federal State Hamburg, all deaths Hamburg citizens ante- or postmortem PCR-confirmed SARS-CoV-2 have been autopsied since outbreak pandemic in Germany. Our evaluation provides systematic overview first...
Abstract Aims Cardiac involvement in COVID-19 is associated with adverse outcome. However, it unclear whether cell-specific consequences are cardiac SARS-CoV-2 infection. Therefore, we investigated heart tissue utilizing situ hybridization, immunohistochemistry, and RNA-sequencing consecutive autopsy cases to quantify virus load characterize COVID-19. Methods results In this study, 95 SARS-CoV-2-positive were included. A relevant the was detected 41/95 deceased (43%). Massive analysis of...
Abstract Analyses of infection chains have demonstrated that severe acute respiratory syndrome coronavirus 2 is highly transmissive. However, data on postmortem stability and infectivity are lacking. Our finding nasopharyngeal viral RNA in 79 corpses showed no time-dependent decrease. Maintained supported by virus isolation up to 35 hours postmortem.
The lack of predictive biomarkers contributes notably to the poor outcomes patients with pancreatic ductal adenocarcinoma (PDAC). Cancer-associated fibroblasts (CAFs) are key components prominent PDAC stroma. Data on clinical relevance CAFs entering bloodstream, known as circulating (cCAFs) scarce. Here, we developed a combined liquid biopsy assay detect cCAFs and tumor cells (CTCs) in metastatic (mPDAC) other gastrointestinal malignancies (mGI). In addition, evaluated plasma hyaluronan (HA)...
Based on a routine ultrasonic screening program of patients suffering from acute abdominal disorders, the efficacy diagnosis intestinal obstruction was assessed prospectively in series 48 patients. In entire proven to suffer ileus, all were correctly diagnosed prior further procedures. cases with marked gaseous distention, typical patterns objectivated using side position The assessment specific mucosal structures permitted identification site mechanical ileus. Sonographic observation real...
Background:Simulator training is an efficient tool to develop surgical novice's basic laparoscopic skills.Currently simulator takes mainly place in simulation centers at hospitals and universities.Additionally, most trainees have use overtime for purposes since it mostly not included during normal working hours.Recent studies also indicated the possibility of low cost at-home surgery, opening up new personalized possibilities.Such modalities support surgeons' initial acquisitions skills as...
A case is reported of progressive inner layer slough the stomach antrum resulting in free perforation following endoscopic injection hemostasis ulcer bleeding using a total 5 ml polidocanol. This rare complication necessitated gastric resection. Relevant etiologic factors favoring this type tissue response to treatment are discussed.
To assess the effectiveness of intestinal tube splinting.The clinical, operative and outcome data 186 patients undergoing 200 splinting procedures from 1973 until 1996 were accumulated in a prospective database. Endpoints perioperative morbidity, mortality incidence subsequent small bowel obstruction (SBO). The latest follow-up performed 1998 updated 197 after 1-25 (median 7) years.In early postoperative period, overall complications was 9%, procedural 2%, repeat surgery 3%. Three died...
An antiserum prepared against a glycoprotein (GP37) extracted from the upper epidermal layers, was used to stain frozen sections of human oral mucosa, normal and abnormal skin by an indirect immunofluorescence technique. On epidermis, this mainly reacted with cytoplasm granular cells, whereas on buccal mucosa recognized antigen observed as scattered dots limited epithelial layers. In diseases, alterations in staining pattern were observed. psoriasis, labelling markedly diminished; contrast,...
In the context of COVID-19-pandemic, mortality and incidence are key determinants to assess transmission dynamics resulting potential threat. Systematic microbiological monitoring deaths provides a fundamental basis particularly underrecording community-acquired mortality. It should be further elucidated whether death cohort previously unreported cases may structurally different from officially registered cases.A systematic reverse transcription (RT) qPCR testing for SARS-CoV‑2 infections...