The similarity between clinical pictures of pigmented actinic keratosis (PAK) and lentigo maligna (LM) is well known.To investigate the frequency dermatoscopic findings suggestive LM/lentigo melanoma (LMM) in other facial skin lesions (FPSL) to assess distinguishing dermoscopic criteria PAK LM.Eighty-nine FPSL were evaluated with conventional dermatoscopy. showing one or more features considered as specific patterns for diagnosis LM/LMM, mainly slate-grey black dots globules, areas,...

Basosquamous carcinoma (BSC) is a rare skin cancer which has areas of basal cell (BCC) and squamous (SCC) transition zone between them. However, dermoscopic features BSC are not well described in the published work, except one study. The aim present study was to better identify clarify findings largest group patients work describe its according histopathologically BCC-dominant, SCC-dominant intermediate categories. Dermoscopic 36 proven their dermatopathological correlates were...

Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder that causes significant decline in quality of life. There are numerous treatment options; however, real-life data on the efficacy these treatments limited. This study was performed two centers to describe clinical characteristics and assess outcome cohort 139 patients with HS. Data demographic characteristics, Hurley stage comorbidities were collected from patient charts evaluated retrospectively. Treatment response...

Epidermolysis bullosa acquisita (EBA) is a rare subepidermal bullous disease. Long-term remission in this disease difficult using current treatments, unlike that patients with other autoimmune diseases.We retrospectively evaluated the effectiveness and side effects of rituximab-intravenous immunoglobulin (IVIg) combination treatment five EBA resistant to conventional treatment.Rituximab (375 mg/m2) was administered for four consecutive weeks patients, their continued IVIg at dose 2...

ABSTRACT Objectives Retinoic acid (RA) has long been used, both topically and systemically, for disorders of keratinization, acne related disorders. In the present study, efficacy tolerability topical RA prepared as a cyclodextrin beta complex (β‐CD) is investigated in 66 vulgaris patients. Methods This randomized, double‐blind, placebo‐controlled study compares nightly application RA/β‐CD hydrogel formulation (0.025%), moisturizing base base, moisturizer or commercial gel (0.05%)...

Abstract Dermatoscopic analysis of melanocytic lesions using the CASH algorithm has rarely been described in literature. The purpose this study was to compare sensitivity, specificity, and diagnostic accuracy rates ABCD rule dermatoscopy, seven‐point checklist, three‐point diagnosis dermatoscopic evaluation on hairy skin. One hundred fifteen 115 patients were examined retrospectively images compared with histopathologic diagnosis. Four algorithms carried out for all lesions. dermatoscopy...

Case 1 A 23‐year‐old woman was diagnosed with chronic myelogenous leukemia in 1997. In 1999, she underwent allogeneic bone marrow transplantation (BMT) from a human leukocyte antigen (HLA)‐matched sibling donor after induction chemotherapy cyclophosphamide and busulfan. At day 46 BMT, discharged medication regimen which included cyclosporine, fluconazole, acyclovir, trimethoprim/sulfamethoxazole. Five months later developed clusters of vesicles pain over the right inframammary infrascapular...

To investigate the efficacy, tolerability and safety of a new oral formulation Sandimmun-Sandimmun Neoral in severe refractory atopic dermatitis an open, multicenter study.The study was conducted three parts. After 2 weeks screening, Sandimmun commenced at dose 3 mg/kg per day continued until remission or for maximum 8 weeks, after which reduced by half another then discontinued. treatment period, patients were followed up first relapse 24 weeks.Twenty-three with (15 females, eight males)...

Abstract Background Mycosis fungoides (MF) and Sezary syndrome (SS) are the most common forms of cutaneous T‐cell lymphoma (CTCL). Various topical systemic therapeutic alternatives available, but there is no standard or definite curative treatment regimen. When making a decision about appropriate modality, age compliance patient, stage disease, accessibility, previous history should be considered. Aim To determine response patients with MF SS to different modalities. Patients were evaluated...

Development of skin neoplasms is the most important complication radiation therapy. There are contradictive reports about type these neoplasms. Squamous cell carcinomas considered frequent tumors arising on chronic radiodermatitis areas, but recent studies have demonstrated that neoplasm occurring in response to ionizing exposure depends several factors. Herein we report a patient who had received low-dose for treatment tinea capitis and developed multiple basal radiated areas after long...

Dermatofibrosarcoma protuberans (DFSP) is an uncommon locally aggressive mesenchymal tumor with a high local recurrence rate. Atrophic DFSP rare variant of characterized by non-protuberant lesion. We report on 23-year-old female, who presented atrophic, asymptomatic macule the right side her back 2 cm in diameter. Dermatoscopic examination revealed homogenous pigment network purplish erythematous background. The histopathological finding incisional biopsy material was consistent DFSP. To our...

Non-melanoma skin cancer (NMSC), predominantly squamous cell carcinoma (SCC) and basal carcinoma, is increasing worldwide. Dermatoscopy, which one of the non-invasive diagnostic techniques, important for early diagnosis NMSC. In this study we aimed to determine dermatoscopic features keratinocyte derived tumors including actinic keratosis (AK), Bowen's disease (BD), keratoacanthoma (KA), SCC correlate findings with pathology. A total 242 lesions from 169 patients were included in...

Abstract: Juvenile hyaline fibromatosis (JHF) is a rare autosomal recessive disease of the connective tissue. It characterized by papulonodular skin lesions, soft tissue masses, gingival hypertrophy, osteolytic bone lesions and flexion contractures large joints. Here, we report 14‐year‐old girl with characteristic clinical features JHF early fatal outcome. Dermatopathologic examination however constantly lacked so‐called hyalin changes in multiple biopsies. According to our experience;...

The sign of Leser-Trélat represents the sudden appearance multiple seborrheic keratoses in association with an underlying malignancy. most common associated neoplasms belong to gastrointestinal tract, mainly stomach and colon. In literature, there is only one case gallbladder carcinoma sign. Thus, hallmark our patient post-renal transplant malignancy-associated Leser-Trélat, which has not been reported before. Here, we report on a 57-year-old man who presented increase number size keratoses,...

Abstract Background Several types of dermatofibroma (DF) have been identified dermatopathologically and with dermatoscopic correlation, the dermatopathology has predictable in limited studies so far. We identify DFs specific structures determine respective dermatopathological correlates. Methods Dermatoscopic dermatopathologic correlation 403 were assessed. A pattern analysis algorithm was used for evaluation, each lesion being evaluated according to 10 patterns further subdivision atypical...