Caitlin Howell

ORCID: 0000-0002-9345-6642
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About
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Research Areas
  • Polymer Surface Interaction Studies
  • Surface Modification and Superhydrophobicity
  • Advanced Cellulose Research Studies
  • Advanced biosensing and bioanalysis techniques
  • Molecular Junctions and Nanostructures
  • Spectroscopy and Quantum Chemical Studies
  • Electrospun Nanofibers in Biomedical Applications
  • Advanced Sensor and Energy Harvesting Materials
  • Lignin and Wood Chemistry
  • DNA and Nucleic Acid Chemistry
  • Plant and Biological Electrophysiology Studies
  • Analytical Chemistry and Sensors
  • Biosensors and Analytical Detection
  • Urinary Tract Infections Management
  • Urinary Bladder and Prostate Research
  • Slime Mold and Myxomycetes Research
  • Bacterial biofilms and quorum sensing
  • Marine Biology and Environmental Chemistry
  • Wood Treatment and Properties
  • 3D Printing in Biomedical Research
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Microfluidic and Bio-sensing Technologies
  • Microplastics and Plastic Pollution
  • Adhesion, Friction, and Surface Interactions
  • Cultural Heritage Materials Analysis

University of Maine
2011-2024

Four Directions Development Corporation
2021

Harvard University
2013-2018

University of Illinois Urbana-Champaign
2018

Aalto University
2018

Karlsruhe Institute of Technology
2010-2013

Heidelberg University
2008-2013

University of Maine System
2009

American University
2008

Abstract Formation of unwanted deposits on steels during their interaction with liquids is an inherent problem that often leads to corrosion, biofouling and results in reduction durability function. Here we report a new route form anti-fouling steel surfaces by electrodeposition nanoporous tungsten oxide (TO) films. TO-modified are as mechanically durable bare highly tolerant compressive tensile stresses due chemical bonding the substrate island-like morphology. When inherently...

10.1038/ncomms9649 article EN cc-by Nature Communications 2015-10-20

There is a dire need for infection prevention strategies that do not require the use of antibiotics, which exacerbate rise multi- and pan-drug resistant infectious organisms. An important target in this area bacterial attachment subsequent biofilm formation on medical devices (e.g., catheters). Here we describe nonfouling, lubricant-infused slippery polymers as proof-of-concept materials are based oil-infused polydimethylsiloxane (iPDMS). Planar tubular geometry silicone substrates can be...

10.1021/ab5000578 article EN publisher-specific-oa ACS Biomaterials Science & Engineering 2014-12-04

Inspired by the long-term effectiveness of living antifouling materials, we have developed a method for self-replenishment synthetic biofouling-release surfaces. These surfaces are created either molding or directly embedding 3D vascular systems into polydimethylsiloxane (PDMS) and filling them with silicone oil to generate nontoxic oil-infused material. When replenished from an outside source, these materials capable self-lubrication continuous renewal interfacial fouling-release layer....

10.1021/am503150y article EN ACS Applied Materials & Interfaces 2014-07-09

Omniphobic coatings are designed to repel a wide range of liquids without leaving stains on the surface. A practical coating should exhibit stable repellency, show no interference with color or transparency underlying substrate and, ideally, be deposited in simple process arbitrarily shaped surfaces. We use layer‐by‐layer (LbL) deposition negatively charged silica nanoparticles and positively polyelectrolytes create nanoscale surface structures that further surface‐functionalized fluorinated...

10.1002/adfm.201401289 article EN Advanced Functional Materials 2014-09-01

The stability and longevity of surface-stabilized lubricant layers is a critical question in their application as low- nonfouling slippery surface treatments both industry medicine. Here, we investigate loss from surfaces under flow water using quantitative analysis visualization, testing the effects underlying type (nanostructured versus flat), well rate physiologically relevant range, type, time. We find losses on order only ng/cm2 closed system, indicating that these interfaces are...

10.1021/cm504652g article EN Chemistry of Materials 2015-02-04

Significance Inspection devices are frequently occluded by highly contaminating fluids that disrupt the visual field and their effective operation. These issues particularly striking in endoscopes, where diagnosis treatment of diseases compromised obscuring operative body fluids. Here we demonstrate application a liquid-infused surface coating strongly repels sticky biological secretions enables an uninterrupted view. Extensive bronchoscopy procedures performed vivo on porcine model shows...

10.1073/pnas.1605272113 article EN Proceedings of the National Academy of Sciences 2016-09-29

Microbial adhesion to medical devices is common for hospital-acquired infections, particularly urinary catheters. If not properly treated these infections cause complications and exacerbate antimicrobial resistance. Catheter use elicits bladder inflammation, releasing host serum proteins, including fibrinogen (Fg), into the bladder, which deposit on catheter.

10.7554/elife.75798 article EN cc-by eLife 2022-03-29

10.1016/j.compositesa.2022.107125 article EN publisher-specific-oa Composites Part A Applied Science and Manufacturing 2022-08-01

The structure and stability of single- double-stranded DNA hybrids immobilized on gold are strongly affected by nucleotide–surface interactions. To systematically analyze the effects these interactions, a set model was prepared in conformations that ranged from end-tethered to directly adsorbed single-stranded (hairpins) characterized surface plasmon resonance (SPR) imaging, X-ray photoelectron spectroscopy (XPS), fluorescence microscopy, near edge absorption fine (NEXAFS) spectroscopy....

10.1021/ac200814y article EN Analytical Chemistry 2011-05-11

The ability to control the properties of bio-inspired liquid-infused surfaces is interest in a wide range applications. Liquid layers created using oil-infused polydimethylsiloxane elastomers offer potentially simple way accomplishing this goal through adjustment parameters such as curing agent ratio and oil viscosity. In work, effect tuning these compositional on infused polymer are investigated, including infusion dynamics, stiffness, longevity face continuous liquid overlayer removal,...

10.1116/1.5039514 article EN publisher-specific-oa Biointerphases 2018-08-09

Bacterial interactions with surfaces are at the heart of many infection-related problems in healthcare. In this work, clinically relevant bacteria immobilized liquid (IL) layers on oil-infused polymers investigated. Although reduce bacterial adhesion all cases, complex and layer under orbital flow conditions uncovered. The number adherent Escherichia coli cells over multiple removal cycles increases compared to static growth conditions, likely due a disruption continuity. Surprisingly,...

10.1002/adhm.201600948 article EN publisher-specific-oa Advanced Healthcare Materials 2016-12-08

Filamentous fungi have been considered as candidates to replace petroleum-based adhesives and plastics in novel composite material production, particularly those containing lignocellulosic materials. However, the nature of role surface mycelium adhesion between components is not well-known. The current study investigated functionality for wood bonding by incubating Trametes versicolor on yellow birch veneers compared lap-shear strengths after hot-pressing evaluate if presence can improve...

10.1021/acsami.0c18165 article EN ACS Applied Materials & Interfaces 2020-12-11
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