A5033127502- Helicobacter pylori-related gastroenterology studies
- Neuroblastoma Research and Treatments
- Galectins and Cancer Biology
- Digestive system and related health
- Neuroendocrine Tumor Research Advances
- Skin and Cellular Biology Research
- Medicinal Plants and Bioactive Compounds
- Anesthesia and Pain Management
- Microbial Metabolites in Food Biotechnology
- Eosinophilic Esophagitis
- Anesthesia and Neurotoxicity Research
- Plant Reproductive Biology
- Cancer Cells and Metastasis
- Erythrocyte Function and Pathophysiology
- Cancer Research and Treatments
- Erythropoietin and Anemia Treatment
- Congenital gastrointestinal and neural anomalies
- Hedgehog Signaling Pathway Studies
- Epigenetics and DNA Methylation
- Glycosylation and Glycoproteins Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cardiac Ischemia and Reperfusion
- Tissue Engineering and Regenerative Medicine
- Dermatologic Treatments and Research
- Metastasis and carcinoma case studies
University of Cincinnati
2018-2022
University of Cincinnati Medical Center
2019-2020
University of Arizona
2020
Sabin Vaccine Institute
2020
University of Pennsylvania
2012
Columbia University
2009
Sonic Hedgehog (Shh), secreted from gastric parietal cells, contributes to the regeneration of epithelium. The recruitment macrophages plays a central role in regenerative process. mechanism that regulates macrophage response injury is largely unknown. Here we tested hypothesis Shh stimulates chemotaxis injured epithelium and regeneration. A mouse model expressing myeloid cell-specific deletion Smoothened (LysMcre/+;Smof/f) was generated using transgenic mice bearing loxP sites flanking Smo...
Background/Hypothesis Prevalence of gastric ulcers increase in the elderly, yet cause age‐associated escalation is unknown. Once Helicobacter pylori (H. pylori) enters stomach lumen, bacterial urease not only converts water & urea to ammonia bicarbonate neutralize acidic environment stomach, but also breaks down protective mucous barrier by breaking mucin. Subsequently, chronic inflammation induced H. infection results epithelial cell death and damage lining, known as a ulcer. We tested...
Background Increased incidence of gastric ulcer disease is often related to frequent nonsteroidal anti‐inflammatory drug (NSAID) use and Helicobacter pylori ( H. ) infection. Studies have shown adheres the epithelium through binding bacterial Sialic Acid‐binding Adhesin (SAbA) glycosylated epithelial mucin receptor sialyl‐Lewis X (S‐Lew ). Our group has reported that CD44v9 emerges during repair after injury where it co‐expressed with markers Spasmolytic Polypeptide/TFF2‐Expressing...