A5011984348- Research on Leishmaniasis Studies
- Leptospirosis research and findings
- Trypanosoma species research and implications
- Urinary Tract Infections Management
- Antibiotic Resistance in Bacteria
- Parasites and Host Interactions
- Pneumonia and Respiratory Infections
- Pelvic floor disorders treatments
- Viral Infections and Vectors
- Mycobacterium research and diagnosis
- Antibiotics Pharmacokinetics and Efficacy
- Infective Endocarditis Diagnosis and Management
- Urinary Bladder and Prostate Research
- Infections and bacterial resistance
- Eosinophilic Disorders and Syndromes
- Fungal Infections and Studies
- Antibiotic Use and Resistance
- Immunodeficiency and Autoimmune Disorders
- Pneumocystis jirovecii pneumonia detection and treatment
- Infectious Diseases and Tuberculosis
- Bacterial biofilms and quorum sensing
- Streptococcal Infections and Treatments
- Cytomegalovirus and herpesvirus research
- Kidney Stones and Urolithiasis Treatments
- Toxoplasma gondii Research Studies
Universidade de São Paulo
2011-2021
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
1955-2018
American Urological Association
2015
Universidade Federal do Paraná
2002-2014
Centro Universitário das Faculdades Metropolitanas Unidas
2012
Hospital Sírio-Libanês
2011
Office of Infectious Diseases
2008
Instituto de Medicina Tropical
2004
Universidade Federal de São Paulo
2002
Hospital Nossa Senhora das Graças
2002
Mucosal leishmaniasis (ML) is an important endemic disease and public-health problem in underdeveloped countries because of its significant morbidity mortality. Increases ecological tourism have extended this to developed countries. This form leishmaniasis, caused by reactivation after primary cutaneous lesion, has a natural history progressive destruction the nasal septa soft hard palates, causing facial disfiguration leading respiratory disturbances. Treatment ML, based on several...
"Lung Lesions in Human Leptospirosis: Microscopic, Immunohistochemical, and Ultrastructural Features Related to Thrombocytopenia" published on Feb 1997 by The American Society of Tropical Medicine Hygiene.
The disc diffusion, Etest and agar dilution techniques were compared to evaluate the antimicrobial susceptibility profile of 70 Stenotrophomonas maltophilia isolates seven agents. S. consecutively collected from May 2000 2002 individual patients, who hospitalized in a private Brazilian hospital. tests carried out interpreted according National Committee for Clinical Laboratory Standards (NCCLS) recommendations. was manufacturer's instructions. There good agreement among distinct testing...
Clostridium difficile is a leading cause of diarrhea in hospitalized patients worldwide. While metronidazole and vancomycin are the most prescribed antibiotics for treatment this infection, teicoplanin, tigecycline nitazoxanide alternatives drugs. Knowledge on antibiotic susceptibility profiles basic step to differentiate recurrence from failure due antimicrobial resistance. Because C. largely unknown Brazil, we aimed determine profile strains cultivated stool samples inpatients with...
Studies assessing the efficacy of liposomal amphotericin B (LAB) in treatment patients with mucosal leishmaniasis (ML) are very scarce literature and an optimal dose regimen has not yet been defined.We performed a retrospective descriptive analysis from records 16 ML treated LAB. The mean daily LAB was 2.5 mg/kg/day.Healing lesion observed 14 (88%) patients. cumulative doses, excluding two failures, were 2265 mg 33 mg/kg.Liposomal 30 to 35 mg/kg able achieve 100% effectiveness.
Liposomal amphotericin B has been used as an alternative treatment of mucosal leishmaniasis, but the optimal dose is not established. We retrospectively reviewed clinical outcome eight patients with leishmaniasis treated liposomal B. The mean total was 35 mg/kg (range 24-50 mg/kg), which resulted in healing all lesions and no recurrences were observed during follow-up period (mean 25 months; range 7-40 months).
Objectives: Mucocutaneous leishmaniasis is widely distributed in Brazil, with Leishmania (Mannia) braziliensis being the major etiologic agent.The currently recommended therapy limited by its parenteral use, high toxicity, and variable efficacy.A clinical pilot study was conducted to analyze itraconazole as an oral alternative for treatment of mucocutaneous leishmaniasis.Methods: Ten patients were enrolled receive 4 mg/kg per day (up 400 mg/d) 6 weeks on outpatient regimen.Diagnosis based...
The present study has intended to contribute the elucidation of pathogenic mechanisms, involved in thrombocytopenia and bleeding diathesis seen course Leptospirosis. group cases included prospective consisted 30 patients with Leptospirosis, admitted Infectious Parasitic Diseases Ward, Hospital das Clínicas, Faculty Medicine, University São Paulo. following possible mechanisms have been considered therefore investigated: platelet consumption, due disseminated intravascular coagulation;...
Mucosal leishmaniasis (ML) is a chronic form of tegumentary leishmaniasis, which causes destructive lesions nasal, pharyngeal, and laryngeal mucosa. We describe case reactivation with simultaneous cutaneous mucosal forms in renal transplanted patient no history prior leishmaniasis. Reactivation after transplantation was not reported Brazil. A 67-year-old woman receiving prednisone 20 mg/day, tacrolimus 1 mycophenolic acid 360 mg/day presented nose edema erythema lesions. Amastigotes were...
Objectives: To compare microscopic and immunologic features in the spleens of patients who died pulmonary hemorrhage shock caused by leptospirosis (11 cases) or Gram-positive/-negative bacterial septic (10 to those from control (12 cases splenectomy). Methodology: Histological red pulp white were analyzed using archived samples a semi quantitative score. Immunohistochemistry was used for recognition immune cell markers, cytokines, caspase-3 Leptospira antigens. Results: The group differed...
Studies evaluating radiologic aspects, local complications, and structural alterations of the paranasal sinus in patients with mucosal leishmaniasis (ML) are lacking. The aim this study was to analyze sinuses ML by using computed tomography (CT) scans. This prospective evaluated 26 Brazil from December 2008 through June 2009. All underwent CT scans sinuses. Paranasal thickening observed 25 (96%). Nasal perforation 17 (65%). Those who received re-treatment showed more abnormalities on scan...
Journal Article Leishmania (Viannia) braziliensis identification by PCR in the state of Para, Brazil Get access H.A. Bacha, Bacha ⁎ aDepartment Infectious Diseases, University São Paulo, Medical School, ⁎Corresponding author. Av. Enéas de Carvalho Aguiar, 470 - 2o. andar -Instituto Medicina Tropical I, Cerqueira Cesar, CEP 05403-000, Paulo -Brazil. Tel.: +55 11 30696530; fax: 30697508. E-mail address:hbacha@terra.com.br (H.A. Bacha). Search for other works this author on: Oxford Academic...
Background/Objectives Mucosal leishmaniasis (ML) is a progressive disease that affects cartilage and bone structures of the nose other upper respiratory tract structures. Complications associated with ML have been described, but there lack studies evaluate structural changes paranasal sinuses in using radiological methods. In this study, we aimed to assess opacification patients treated any anatomical face multidetector computed tomography scans (MDCT) sinuses. We compared findings control...
Rothia aeria is an uncommon pathogen mainly associated with endocarditis in case reports. In previous reports, by R. was complicated central nervous system embolization. the we report herein, diagnosed after acute self-limited diarrhea. addition to common translocation of from oral cavity, hypothesize possibility intestinal translocation. Matrix-assisted laser desorption ionization-time flight mass spectrometry and genetic sequencing are important tools that can contribute early more...