A5051473778- Radiopharmaceutical Chemistry and Applications
- Nanoplatforms for cancer theranostics
- Photodynamic Therapy Research Studies
- Porphyrin and Phthalocyanine Chemistry
- Medical Imaging Techniques and Applications
- Orthopedic Infections and Treatments
- Estrogen and related hormone effects
- Peptidase Inhibition and Analysis
- Medical Imaging and Pathology Studies
- Chemical Reactions and Isotopes
- Nuclear Physics and Applications
- HER2/EGFR in Cancer Research
- Nanoparticle-Based Drug Delivery
- Inflammatory mediators and NSAID effects
- Pharmacological Receptor Mechanisms and Effects
- Neuropeptides and Animal Physiology
- Radiation Shielding Materials Analysis
- Metal complexes synthesis and properties
- Lung Cancer Research Studies
- Thyroid Disorders and Treatments
- Orthopaedic implants and arthroplasty
- Bone Tissue Engineering Materials
- Infective Endocarditis Diagnosis and Management
- Cancer Treatment and Pharmacology
- Ion channel regulation and function
Ege University
2015-2024
Friedrich-Alexander-Universität Erlangen-Nürnberg
2023
Materials Science & Engineering
2023
Institute of Nuclear Physics
1998
In recent years, phthalocyanines (Pcs) have been widely used as photosensitizer in photodynamic therapy applications. Because of their strong absorptions the near-infrared region (640-700 nm). The integration phthalocyanine derivatives to a nanoparticle is expected be efficient way improve activity on targeted tissue. It known that integrated molecules not only show better accumulation tumor tissue but also reduce toxicity healthy tissues. this study, ZnPc molecule was synthesized and TiO2...
In general, lead is used as shielding material for protection against radiation. spite of its high density, toxic and aprons are very heavy personal shielding. Thus, there a need nontoxic, light, environmental friendly radiation-shielding materials. Polymers cannot be effective gamma radiation on their own. High-density metal wolfram carbide could useful radiation, boron also neutron this study, high-density polyethylene, carbide, can mixed in certain amounts composite discs obtained way....
Photodynamic therapy (PDT) is a non-invasive and innovative cancer based on the photodynamic effect. In this study, we sought to determine singlet oxygen production, intracellular uptake, in vitro potential of Cetixumab-targeted, zinc(II) 2,3,9,10,16,17,23,24-octa(tert-butylphenoxy))phthalocyaninato(2-)-N29,N30,N31,N32 (ZnPcOBP)-loaded mesoporous silica nanoparticles against pancreatic cells.The quantum yield (ΦΔ) value ZnPcOBP was found be 0.60 toluene. cellular studies were performed dark-...
A series of imidazolium bromide salts (NIM-Br 1a, 1b and 1c) bearing different lengths alkyl chains were synthesized theirin vitro antibacterial activities determined by measuring the minimum inhibitory concentration (MIC) values for Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa Enterococcus faecalis. In addition, these derivatives also evaluated against biofilm produced bacterial strains. All compounds found to be effective Gram-positive Gram-negative bacteria, more on S....
For synthesizing metal–organic molecules with pro‐drug properties to prevent the accumulation of amyloid beta (Aβ 1–42 ), which is a feature neurodegenerative Alzheimer's disease, two new Schiff bases imine/amine donors 2‐([3,3‐diphenylalidene]amino)‐N,N‐dimethylethane‐1‐amine and N,N‐dimethyl‐2‐([quinolin‐4‐ylmethylene]amino)ethane‐1‐amine, as well their novel Pt (II) complexes (I II), were synthesized characterized via Fourier transform infrared spectroscopy, 1 H‐ 13 C‐nuclear magnetic...
Introduction The use of spinal implants for the treatment back disorders is largely affected by insurgence infections at implantation site. Antibacterial coatings have been proposed as a viable solution to limit such infections. However, despite being effective short-term, conventional lack ability prevent medium and long-term. Hydrogel-based drug delivery systems may represent controlling release loaded antibacterial agents while improving cell integration. Agarose, in particular,...