A5091314361- Mycobacterium research and diagnosis
- Tuberculosis Research and Epidemiology
- Antibiotic Resistance in Bacteria
- Viral Infections and Outbreaks Research
- Disaster Response and Management
- Healthcare Systems and Reforms
- COVID-19 epidemiological studies
- Global Maternal and Child Health
- Nanoparticles: synthesis and applications
- Microbial bioremediation and biosurfactants
- Microbial Metabolism and Applications
- Bone Tissue Engineering Materials
- Endometrial and Cervical Cancer Treatments
- COVID-19 Pandemic Impacts
- Liver Disease and Transplantation
- Global Public Health Policies and Epidemiology
- Uterine Myomas and Treatments
- Zoonotic diseases and public health
- Glycosylation and Glycoproteins Research
- Diagnosis and treatment of tuberculosis
- Adolescent and Pediatric Healthcare
- Adolescent Sexual and Reproductive Health
- Hepatitis Viruses Studies and Epidemiology
- Biosensors and Analytical Detection
- Blood Pressure and Hypertension Studies
Heidelberg University
2021-2024
University Hospital Heidelberg
2022-2024
Global Policy Institute
2023
University of California, Los Angeles
2020
Partners In Health
2019
B.J. Medical College
2018
Harvard University
2011-2016
International Centre for Diarrhoeal Disease Research
2016
DNA methylation regulates gene expression in many organisms. In eukaryotes, is associated with repression, while it exerts both activating and repressive effects the Proteobacteria through largely locus-specific mechanisms. Here, we identify a critical methyltransferase M. tuberculosis, which term MamA. MamA creates N6-methyladenine six base pair recognition sequence present approximately 2,000 copies on each strand of genome. Loss reduces number genes. Each has site located at conserved...
Global control of tuberculosis has become increasingly complicated with the emergence multidrug-resistant strains Mycobacterium First-line treatments are anchored by two antibiotics, rifampin and isoniazid. Most resistance occurs through acquisition missense mutations in resistance-determining region, an 81-base pair region encoding binding site on β subunit RNA polymerase (rpoB). Although these confer a survival advantage presence rifampin, they may alter normal process transcription,...
Objectives To examine the knowledge, attitudes and practices (KAP) of COVID-19 rural urban residents in Liberia to inform development local social behaviour change communication strategies. Design Cross-sectional, mixed-mode (online telephone) survey using non-probability sampling. Setting All 15 counties with a focus on Maryland County. Participants From 28 May June 2020, data were collected from total 431 adults aged 18 years older (telephone 288 (66.8%); online 143 (33.2%)) out 741...
Abstract Background Health care workers (HCW) are more likely to be exposed Ebola virus (EBOV) during an outbreak compared people in the general population due close physical contact with patients and potential exposure infectious fluids. However, not all will fall ill. Despite evidence of subclinical paucisymptomatic disease (EVD), prevalence associated risk factors remain unknown. Methods We conducted a serosurvey among HCW Boende, Tshuapa Province, Democratic Republic Congo. Human...
Background: Abnormal uterine bleeding is one of the most frequent problems in life an adult female. Accurate analysis endometrium & localization intrauterine lesion goal to effective management better outcome problem. Aims Objective: To evaluate various histopathological features D C and/or hysterectomy patients presenting with abnormal and find efficacy as a better, cost minimally invasive tool for screening AUB. Materials Methods: The present study was conducted Department Pathology,...
We estimated the proportion of maternal deaths in Bangladesh associated with acute onset jaundice. used verbal autopsy data from a nationally representative mortality survey to calculate jaundice and compared it previously published estimates. Of all between 2008 2010, 23% were jaundice, 19% 1998 2001. Approximately one five was preceded by unchanged 10 years. Our findings highlight need better understand etiology these Bangladesh.
Aim For over 15 years, the pharmaceutical industry has been engaged in developing medicines for children to comply with European Union (EU) and United States (US) regulatory requirements. We assessed authorization availability of these countries without paediatric obligations. Special attention was given formulations. Methods Medicines were sampled from US Food Drug Administration Agency websites. carried out systematic content analysis product information compared labelling Australia,...
The 2014 outbreak of the Ebola virus disease highlighted importance overhauling and transforming healthcare systems in West Africa to improve ability individual countries deal with infectious diseases. As part this effort, November 2016 African Health Organization (WAHO) began process institutionalizing One (OH) approach health security across Economic Community States (ECOWAS). lack clear metrics evaluation frameworks measure progress OH implementation has been reported as a challenge....
INTRODUCTION: Hairy cell leukemia (HCL) is an uncommon chronic B-cell lymphoproliferative disorder. It affects primarily elderly men and presents with splenomegaly, pancytopenia monocytopenia. has to be differentiated from various disorders (CLPDs) because of different protocol treatment clinical course.MATERIALS AND METHODS : This study included 18 cases HCL out 300 CLPDs diagnosed over a period 4 years (2009-2012) at tertiary cancer centre. All were evaluated for history, signs symptoms,...
Rigorous evaluations of health system interventions to strengthen hypertension and cardiovascular disease (CVD) care remain scarce in sub-Saharan Africa. This study aims evaluate the reach, effectiveness, adoption / acceptability, implementation fidelity, cost, sustainability Ghana Heart Initiative (GHI), a multicomponent supply-side intervention improve Ghana.This adopts mixed- multi-methods design comparing effects GHI 42 facilities (i.e. primary, secondary tertiary) Greater Accra Region...