- Thyroid Disorders and Treatments
- Thyroid Cancer Diagnosis and Treatment
- Growth Hormone and Insulin-like Growth Factors
- Thyroid and Parathyroid Surgery
- Pituitary Gland Disorders and Treatments
- Head and Neck Anomalies
- Neuroendocrine Tumor Research Advances
- BRCA gene mutations in cancer
- Ion channel regulation and function
- Bone health and treatments
- Vitamin D Research Studies
- Medical and Biological Sciences
- Radiation Dose and Imaging
- Neonatal Health and Biochemistry
- Diabetes and associated disorders
- Radiopharmaceutical Chemistry and Applications
- Parathyroid Disorders and Treatments
- Blood disorders and treatments
- Bone health and osteoporosis research
- Nitric Oxide and Endothelin Effects
- Ophthalmology and Eye Disorders
- Ovarian cancer diagnosis and treatment
- Nutrition, Genetics, and Disease
- Estrogen and related hormone effects
- Neuroscience of respiration and sleep
Johns Hopkins Medicine
2015-2024
Johns Hopkins University
2015-2024
Johns Hopkins Hospital
1986-2021
Diabetes Australia
2019-2021
University of Baltimore
2020
National and Kapodistrian University of Athens
2019
University of Pennsylvania
2015
Apple (United Kingdom)
2014
Samsung (United Kingdom)
2014
Walter Reed National Military Medical Center
2013
Thyroid nodules are a common clinical problem, and differentiated thyroid cancer is becoming increasingly prevalent. Since the publication of American Association's guidelines for management these disorders was published in 2006, large amount new information has become available, prompting revision guidelines.Relevant articles through December 2008 were reviewed by task force categorized topic level evidence according to modified schema used United States Preventative Services Task Force.The...
Background: Thyrotoxicosis has multiple etiologies, manifestations, and potential therapies. Appropriate treatment requires an accurate diagnosis is influenced by coexisting medical conditions patient preference. This document describes evidence-based clinical guidelines for the management of thyrotoxicosis that would be useful to generalist subspecialty physicians others providing care patients with this condition. Methods: The American Thyroid Association (ATA) previously cosponsored were...
a. Goals of therapy b.Role preoperative staging with diagnostic testing c.Surgery for differentiated thyroid cancer iii.Extent initial surgery iii.Completion thyroidectomy d.Pathological and clinical systems e. Postoperative radioiodine remnant ablation iii.Modes hormone withdrawal iii.Role scanning before iii.Radioiodine dosage iv.Use recombinant human thyrotropin iv.Role low iodine diets vi.Performance post scans f.Thyroxine suppression g.Role adjunctive external beam radiation or...
A number of recent advances in our understanding thyroid physiology may shed light on why some patients feel unwell while taking levothyroxine monotherapy. The purpose this task force was to review the goals therapy, optimal prescription conventional sources dissatisfaction with evidence treatment alternatives, and relevant knowledge gaps. We wished determine whether there are sufficient new data generated by well-designed studies provide reason pursue such therapies change current standard...
Thyrotoxicosis has multiple etiologies, manifestations, and potential therapies. Appropriate treatment requires an accurate diagnosis is influenced by coexisting medical conditions patient preference. This article describes evidence-based clinical guidelines for the management of thyrotoxicosis that would be useful to generalist subspeciality physicians others providing care patients with this condition.The development these was commissioned American Thyroid Association in association...
This analysis was performed to determine the effect of initial therapy on outcomes thyroid cancer patients. The study setting a prospectively followed multi-institutional registry. Patients were stratified as low risk (stages I and II) or high III IV). Treatments employed included near-total thyroidectomy, administration radioactive iodine, hormone suppression therapy. Outcome measures overall survival, disease-specific disease-free survival. Near-total aggressive each independently...
Background: The primary goals of this interdisciplinary consensus statement are to review the relevant anatomy central neck compartment, identify nodal subgroups within compartment commonly involved in thyroid cancer, and define a consistent terminology dissection. Summary: most lymph nodes carcinoma prelaryngeal (Delphian), pretracheal, right left paratracheal basins. A dissection includes comprehensive, compartment-oriented removal pretracheal at least one node basin. designation should be...
Recombinant human TSH has been developed to facilitate monitoring for thyroid carcinoma recurrence or persistence without the attendant morbidity of hypothyroidism seen after hormone withdrawal. The objectives this study were compare effect administered recombinant with withdrawal on results radioiodine whole body scanning (WBS) and serum thyroglobulin (Tg) levels. Two hundred twenty-nine adult patients differentiated cancer requiring WBS studied. Radioiodine Tg measurements performed...
To detect recurrent disease in patients who have had differentiated thyroid cancer, periodic withdrawal of hormone therapy may be required to raise serum thyrotropin concentrations stimulate tissue so that radioiodine (iodine-131) scanning can performed. However, causes hypothyroidism. Administration recombinant human stimulates without requiring the discontinuation therapy.
The indications for treating patients with subclinical hypothyroidism (normal serum thyroxine and free levels, but elevated thyrotrophin levels) are poorly defined. In this study, 33 were randomly assigned in a double-blind manner to receive placebo or L-thyroxine therapy followed 1 year thyroid function tests, lipid measurements, basal metabolic rate systolic time interval determinations, questionnaire on hypothyroid symptoms. group showed no changes peripheral indices of hormone action....
<h3>Objective.</h3> —To develop a set of minimum clinical guidelines for use by primary care physicians in the evaluation and management patients with hyperthyroidism hypothyroidism. <h3>Participants.</h3> —Guidelines were developed nine-member ad hoc Standards Care Committee American Thyroid Association (the authors this article). The participants selected committee chair president on basis their experience. members represented different geographic areas within United States, order to take...
BACKGROUND A novel prognostic staging classification encompassing all forms of thyroid carcinoma was created for the National Thyroid Cancer Treatment Cooperative Study (NTCTCS) Registry, with goal prospective validation and comparison other available classifications. METHODS Patient information recorded prospectively from 14 institutions. Clinicopathologic based on patient age at diagnosis, tumor histology, size, intrathyroidal multifocality, extraglandular invasion, metastases,...
More than two decades have passed since members from the American Thyroid Association (ATA), European Association, and Japan were surveyed on management practices for patients with hyperthyroidism due to Graves' disease (GD). We sought document current in of GD compare these results both those documented earlier surveys practice recommendations made 2011 ATA/American Clinical Endocrinologists (AACE) guidelines. Lastly, we examine differences among international U.S.-based endocrine...