A5049385010- Pregnancy and preeclampsia studies
- Nitric Oxide and Endothelin Effects
- Birth, Development, and Health
- Cardiac, Anesthesia and Surgical Outcomes
- Bacterial Identification and Susceptibility Testing
- Reproductive System and Pregnancy
- Anesthesia and Neurotoxicity Research
- Vitamin D Research Studies
- Cancer Risks and Factors
- Respiratory viral infections research
- Mercury impact and mitigation studies
- Heavy Metal Exposure and Toxicity
- Eicosanoids and Hypertension Pharmacology
- Renin-Angiotensin System Studies
- Antibiotic Use and Resistance
- Antibiotic Resistance in Bacteria
Universidade Estadual Paulista (Unesp)
2022-2024
Instituto Adolfo Lutz
2022
Abstract Lead (Pb) reduces NO bioavailability, impairs the antioxidant system, and increases generation of reactive oxygen species (ROS). Pb‐induced oxidative stress may be responsible for associated endothelial dysfunction. Sildenafil has shown nitric oxide (NO)‐independent action, including effects. Therefore, we examined effects sildenafil on stress, reductions dysfunction in hypertension. Wistar rats were distributed into three groups: Pb, Pb + Sham. Blood pressure endothelium‐dependent...
Pre-eclampsia (PE) is a hypertensive disorder of pregnancy and has been associated with placental growth restriction. The pre-eclamptic placenta releases free radicals to maternal circulation, thus increasing oxidative stress. An impaired redox state leads reduction in circulating nitric oxide (NO) levels activation extracellular matrix metalloproteinases (MMPs). However, MMPs induced by stress still unclear PE. Antioxidant effects have demonstrated the use pravastatin. Therefore, we...
Preeclampsia (PE) is a hypertensive disorder of pregnancy and associated with increases in soluble fms-like tyrosine kinase-1 (sFlt-1) reductions nitric oxide (NO) levels. Placental ischemia hypoxia are hypothesized as initial pathophysiological events PE. Nitrite (NO metabolite) may be recycled back to NO ischemic hypoxic tissues. Therefore, this study examined the sodium nitrite effects an experimental model Pregnant rats received saline (Preg group) or + Na-Nitrite group). submitted...
Abstract Volatile anesthetics may cause vascular dysfunction; however, underlying effects are unclear. The aim of the present study was to investigate whether sevoflurane and isoflurane affect function, nitric oxide (NO) bioavailability, biomarkers oxidative stress inflammation. Wistar rats were divided into three experimental groups: Not anesthetized (control group) or submitted anesthesia with (Iso (Sevo group). Hemodynamic parameters monitored during anesthesia, blood gas values...
Preeclampsia is a maternal hypertension disorder associated with vascular dysfunction and fetal placental growth restrictions. Placental ischemia suggested as the primary trigger of preeclampsia-associated impairments both endothelium-derived nitric oxide (NO) activity extracellular matrix metalloproteinase-2 (MMP-2). Reduced uteroplacental perfusion pressure (RUPP) model preeclampsia. Reduction sodium nitrite to NO may occur during ischemic conditions. However, effects in RUPP preeclampsia...
Introdução: O vírus Influenza, um dos maiores desafios de saúde pública do mundo, causa epidemias anuais recorrentes com infecções respiratórias agudas que apresentam manifestações variam quadros leves a complicações fatais. Objetivos: Caracterizar o perfil epidemiológico pacientes hospitalizados Síndrome Respiratória Aguda Grave (SRAG) por Influenza na região Noroeste Paulista Brasil. Adicionalmente, verificar sazonalidade da gripe e prevalência população desta região. Métodos: estudo...
Introduction: KPC and NDM carbapenemases production is an important enzymatic mechanism of resistance to carbapenens in bacteria belonging the Enterobacteriaceae family. These enzymes degrade virtually all beta-lactam antibiotics are encoded by blaKPC blaNDM genes, which can be mobile genetic elements such as plasmids transposons. Objectives: This study evaluated positivity rate presence genes carbapenem-resistant enterobacteria received at Instituto Adolfo Lutz (IAL) São José do Rio Preto,...