Jianguang Li

ORCID: 0000-0002-9506-006X
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About
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Research Areas
  • Photonic and Optical Devices
  • Geomechanics and Mining Engineering
  • Rock Mechanics and Modeling
  • Semiconductor Lasers and Optical Devices
  • Advanced Fiber Optic Sensors
  • Geoscience and Mining Technology
  • Geotechnical and Geomechanical Engineering
  • Grouting, Rheology, and Soil Mechanics
  • Geotechnical Engineering and Underground Structures
  • Geotechnical Engineering and Analysis
  • Soil, Finite Element Methods
  • Photonic Crystals and Applications
  • Optical Network Technologies
  • Fish Biology and Ecology Studies
  • Advanced Fiber Laser Technologies
  • Echinoderm biology and ecology
  • Nonlinear Photonic Systems
  • Civil and Geotechnical Engineering Research
  • Railway Systems and Energy Efficiency
  • Transportation Planning and Optimization
  • Drilling and Well Engineering
  • Spine and Intervertebral Disc Pathology
  • Nonlinear Waves and Solitons
  • Aquaculture Nutrition and Growth
  • Bioactive natural compounds

Aerospace Center Hospital
2022-2024

Qingdao University of Science and Technology
2013-2024

Quzhou University
2015-2024

Second Affiliated Hospital of Xinjiang Medical University
2024

Xinjiang Medical University
2016-2024

Taiyuan University of Technology
2024

Southwest Forestry University
2021-2023

Xinjiang University of Science and Technology
2022-2023

Xinjiang University
2022-2023

AviChina Industry & Technology (China)
2020-2023

The effect of a commercially available compound probiotics product containing Bacillus subtilis YB-1 (50%) and cereus YB-2 fed to sea cucumbers, Apostichopus japonicus (Selenka) on challenge infections non-specific immune responses was assessed. Sea cucumbers (were randomly allocated into nine aquariums at density 30 per tank triplicate groups) were diets 0 (control), 107 1010 cfu (g diet)−1 the mixture for 32 days. growth factors immunological parameters measured. In addition, effects...

10.1111/are.12453 article EN Aquaculture Research 2014-04-11

Effective treatment of bacterial biofilm-related infections is a great challenge for the medical community. During formation biofilms, bacteria excrete extracellular polymeric substances (EPS), including polysaccharides, proteins, nucleic acids, etc., to encapsulate themselves and form "fort-like" structure, which greatly reduces efficiency therapeutic agents. Herein, we prepared nanoagent (MnO2-amylase-PEG-ICG nanosheets, MAPI NSs) with biofilm degradation capability efficient photothermal...

10.1039/d2bm01570f article EN Biomaterials Science 2022-12-09

Our previous research demonstrated that tilianin protects the myocardium in a myocardial ischemia reperfusion injury (MIRI) rat model and has prominent pharmacological potential as cardiovascular drug. study aimed to investigate molecular signaling implicated improvement of survival induced by tilianin, flavonoid antioxidant. Tilianin (2.5, 5, 10 mg/kg/d) or saline was orally administered rats for 14 days. On 15th day, ligating left anterior descending artery 45 min, followed 4 h...

10.1371/journal.pone.0193845 article EN cc-by PLoS ONE 2018-03-14

Abstract The paper’s primary purpose is to optimize the performance (speed/accuracy) of vehicle detection. dataset Vehicle2020 used in this paper divided into ten different classes. Intersection over Union ( IoU ) usually as a standard evaluate accuracy detection specific dataset. However, object algorithm still shortcomings. further improved and called new EIoU . Finally, neural network structure was redesigned, which VehicleNet. experimental results show that evaluation framework can...

10.1088/1742-6596/1924/1/012001 article EN Journal of Physics Conference Series 2021-05-01

Reef limestone is a biogenic sedimentary rock widely distributed in coral reef areas, acting as an important foundation for coast construction. Due to its special origin, different from conventional rocks both terms of structure and mechanical properties. In this study, mesoscale uniaxial compression experiments with five loading directions were conducted on two kinds limestones the Maldives Islands South China Sea, respectively. The real-time high-resolution videos images failure processes...

10.1016/j.jrmge.2023.02.027 article EN cc-by-nc-nd Journal of Rock Mechanics and Geotechnical Engineering 2023-04-20

Introduction Glioblastoma (GBM) presents significant challenges due to its malignancy and limited treatment options. Precision requires subtyping patients based on prognosis. Disulfidptosis, a novel cell death mechanism, is linked aberrant glucose metabolism disulfide stress, particularly in tumors expressing high levels of SLC7A11. The exploration disulfidptosis may provide new perspective for precise diagnosis glioblastoma. Methods Transcriptome sequencing was conducted samples from GBM...

10.3389/fimmu.2024.1362543 article EN cc-by Frontiers in Immunology 2024-02-26

The nuclear factor erythroid-2-related 2 (Nrf2) pathway has been considered as a potential target for neuroprotection in stroke. aim of present study was to determine whether corilagin, novel Nrf2 activator, can protect against ischemia-reperfusion injury and explore the underlying mechanism involved. In vivo, rats exposed middle cerebral artery occlusion were applied establish an ischemic stroke model. Posttreatment corilagin significantly reduced infarct volumes apoptotic cells well...

10.18632/oncotarget.22023 article EN Oncotarget 2017-10-24

Subthalamic nucleus (STN) deep brain stimulation (DBS) has been proven to be an alternative target choice for refractory isolated cervical dystonia (CD). However, assessments of its short and long-term safety, efficacy, sustained effectiveness have limited few reports. Here, we evaluated nine consecutive CD patients who underwent bilateral STN DBS accepted follow-up in this retrospective study. Seven time points were used see the Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS)...

10.1038/s41598-022-11841-1 article EN cc-by Scientific Reports 2022-05-10

Endothelial cells of cerebral capillaries forming the blood-brain barrier play an important role in pathogenesis and therapy Alzheimer’s disease. Amyloid-β peptides are key pathological elements development this Apigenin (4’,5,7-tetrahydroxyflavone) is a plant flavonoid pharmacologically active agent that can be isolated from several species. In present study, effects apigenin obtained medicinal Elsholtzia rugulosa (Labiatae) on primary cultured rat microvascular endothelial (CMECs) mediated...

10.3390/molecules16054005 article EN cc-by Molecules 2011-05-13

The cast-in-place (CIP) pile is a type of deep foundation that has been widely used in various soils. However, the performance CIP dynamically compacted (DC) soil-rock mixtures rarely investigated. This study presents field investigation on piles DC treated mixtures. First, 30-meter-thick mixture layer site was improved using (maximum energy level =10,000 kN·m) grouting area and non-grouting area. Second, two groups six with diameter 1.2 m length 34 were constructed. After that, static load...

10.1016/j.cscm.2024.e03267 article EN cc-by-nc-nd Case Studies in Construction Materials 2024-05-10

Soil conditioning is of great significance for tunneling in soft ground with earth pressure balance shield (EPBS) machines, which leads to safe, highly efficient, and high-quality tunneling. To study the effects soil on properties a clay-sand-gravel mixed encountered an EPBS project Beijing, series geotechnical test methods was carried out based laboratory this paper. The decay behaviors foam particles generated by Waring-Blender method were studied first using image particle analysis...

10.3390/app10093300 article EN cc-by Applied Sciences 2020-05-09

Composite rocks are easily encountered in a wide range of geotechnical construction projects. Understanding their mechanical properties and failure modes is very important to ensure project quality safety. This study conducted analysis assess the stress distribution composite rock with horizontal interlayer predicted possible modes. Uniaxial compression tests were carried out on samples reveal properties. It was concluded that thick failed more than thin interlayer. Four potential related...

10.1038/s41598-021-02331-x article EN cc-by Scientific Reports 2021-11-24

Dynamic compaction (DC) is an efficient ground treatment technique that has been widely used for different soil types, however, the investigation on performance of high energy level DC soil-rock mixture backfills rare so far. This study presents a field effectiveness with maximum 10,000-kN·m mixtures in southwestern China. Field tests, including surface wave test (SWT), super heavy dynamic penetration (SH-DPT), and plate load (PLT) were conducted to evaluate under conditions. The improvement...

10.1016/j.cscm.2022.e01734 article EN cc-by-nc-nd Case Studies in Construction Materials 2022-12-05

Work function engineering, a precise tuning of the work function, is essential to achieve devices with best performance. In this study, we demonstrate simple technique deposit graphene on insulators in situ controlled boron doping tune function. At temperature higher than 1000 °C, atoms substitute carbon sites lattice neighboring atoms, leading p-type behavior. Interestingly, involvement vapor into system can effectively accelerate reaction between nickel and methane, achieving fast...

10.1021/jp508365h article EN The Journal of Physical Chemistry C 2014-10-04

A high-performance monolithic integrated wavelength division multiplexing silicon (Si) photonics receiver chip is fabricated on a silicon-on-insulator platform. The has 25-channel Si nanowire-arrayed waveguide grating, and each channel with high-speed Ge-on-Si photodetector. central wavelength, optical insertion loss, cross talk of the array grating are 1550.6 nm, 5–8 dB, −12–−15  dB, respectively. photodetectors show low dark current density 16.9  mA/cm2 at −1  V high responsivity 0.82 A/W...

10.1364/prj.7.000659 article EN Photonics Research 2019-05-22

Estimation of ultimate bearing capacity (UBC) pre-stressed high-strength concrete (PHC) pipe pile is critical for optimizing design and construction. In this study, a standard penetration test (SPT), static cone (CPT) load (SLT) were carried out to assess, determine compare the UBC PHC embedded in saturated sandy layers at different depths. The was calculated with three methods including JGJ94-2008 method, Meyerhof method Schmertmann based on in-situ blow count (N) SPT (SPT-N) which higher...

10.3390/app10186269 article EN cc-by Applied Sciences 2020-09-09

To alleviate the environmental problems caused by scrap tire and tailings disposal, performance of recycled polymer fiber (RTPF)-reinforced cemented paste backfill (CPB) was investigated. Ordinary CPB, commercial poly-propylene (CPPF) reinforced CPB were also investigated for comparison. Slump tests, unconfined compression tests a cost-benefit analysis conducted. The results indicate that flowability RTPF-reinforced decreased with increasing content. failure strain, compressive strength,...

10.3390/polym14040708 article EN Polymers 2022-02-12

Chlorogenic acid (CGA) is a phenylpropyl substance synthesized through the shikimic pathway. In addition to its anti-tumor, anti-inflammatory, and antioxidant abilities, CGA also has immunomodulatory effects. The aim of present study investigate therapeutic effects on skin damage arthritis caused by systemic lupus erythematosus (SLE) in an MRL/lpr mouse model. SLE model, female mice at age 10 weeks old were treated with daily or cyclophosphamide (CTX) weekly via intraperitoneal injection for...

10.3390/ph15111327 article EN cc-by Pharmaceuticals 2022-10-27
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