A5068890896- Head and Neck Cancer Studies
- Esophageal Cancer Research and Treatment
- Nutrition and Health in Aging
- Frailty in Older Adults
- Ocular Diseases and Behçet’s Syndrome
- Oral health in cancer treatment
- Lung Cancer Research Studies
- Glioma Diagnosis and Treatment
- Liver Disease Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Neurosurgical Procedures and Complications
- Hepatocellular Carcinoma Treatment and Prognosis
- Salivary Gland Disorders and Functions
- Cancer Risks and Factors
- Vasculitis and related conditions
- Cytomegalovirus and herpesvirus research
- Intracranial Aneurysms: Treatment and Complications
- Radiomics and Machine Learning in Medical Imaging
- Retinal and Macular Surgery
- Dysphagia Assessment and Management
- Systemic Lupus Erythematosus Research
- Acne and Rosacea Treatments and Effects
- Cholinesterase and Neurodegenerative Diseases
- Herpesvirus Infections and Treatments
- Effects of Radiation Exposure
Korea Advanced Institute of Science and Technology
2025
Samsung Medical Center
2014-2021
Sungkyunkwan University
2013-2021
Chosun University
2017-2018
Jeju National University
2018
Jeju National University Hospital
2018
Severance Hospital
2017
Yonsei University
2017
Samsung (South Korea)
2013
The relationship between sarcopenia, characterized by loss of muscle mass and strength, survival outcomes esophageal cancer is controversial. This study aimed to assess the effect sarcopenia skeletal on overall (OS) recurrence-free (RFS) patients.We retrospectively collected medical records 248 male patients diagnosed with squamous cell who underwent neoadjuvant chemoradiotherapy (NACRT) followed surgery. We measured cross-sectional area at L3 vertebra level using computed tomography images...
Background/Objectives: We aimed to compare the salivary gland volume changes following intensity-modulated radiation therapy (IMRT) alone versus IMRT/intensity-modulated proton (IMPT) combination in oropharyngeal cancer (OPC). Methods: retrospectively reviewed 78 OPC patients who underwent definitive RT with ipsilateral neck irradiation. techniques were either IMRT or IMRT/IMPT combination. Salivary volumes over time relation dry mouth symptom evaluated. Results: Patients’ characteristics...
Excessive muscle loss is an important prognostic factor in esophageal cancer patients undergoing neoadjuvant chemoradiotherapy (NACRT), as reported our previous research.In this pilot study, we prospectively tested the feasibility of a health coaching mobile app for preventing malnutrition and patient population.Between July 2019 May 2020, enrolled 38 male with scheduled NACRT. For 8 weeks from start radiotherapy (RT), used Noom, that interactively provided online advice about food intake,...
<b>Introduction:</b> The response to acetylcholinesterase inhibitors (AChEIs) of Alzheimer's disease (AD) patients varies depending on the genetic characteristics patient. We have examined association AChEIs and polymorphisms in AD patients. <b>Methods:</b> 158 with underwent treatment AChEIs, therapeutic effect was assessed Korean version Mini Mental State Examination (K-MMSE). 25 SNPs located 3 genes (<i>CHAT, CHT</i> <i>ACHE</i>) changes K-MMSE score analyzed. <b>Results:</b>...
This study aimed to investigate the performance of a deep learning-based survival-prediction model, which predicts overall survival (OS) time glioblastoma patients who have received surgery followed by concurrent chemoradiotherapy (CCRT). The medical records had and CCRT between January 2011 December 2017 were retrospectively reviewed. Based on our inclusion criteria, 118 selected semi-randomly allocated training test datasets (3:1 ratio, respectively). A convolutional neural network-based...
Abstract Background Excessive skeletal muscle loss during neoadjuvant concurrent chemoradiotherapy (NACRT) is significantly related to survival outcomes of oesophageal cancer. However, the conventional method for measuring mass requires computed tomography (CT) images, and calculation process labour‐intensive. In this study, we built machine‐learning models predict excessive loss, using only body index data blood laboratory test results. Methods We randomly split 232 male patients treated...
Purpose: To report the early clinical outcomes of combining intensity-modulated radiation therapy (IMRT) and proton (IMPT) in comparison with IMRT alone treating oropharynx cancer (OPC) patients. Materials Methods: The medical records 148 OPC patients who underwent definitive radiotherapy (RT) concurrent systemic therapy, from January 2016 till December 2019 at Samsung Medical Center, were retrospectively reviewed. During 5.5 weeks’ RT course, initial 16 (or 18) fractions delivered by all...
The effectiveness of thoracic radiation therapy (TRT) in extensive-stage small cell lung cancer (ES-SCLC) patients is increasingly reported, but there no definite consensus on its application. aim this study was to identify factors associated with better outcomes TRT among ES-SCLC, focusing whether a higher dose could improve treatment outcome.The medical records 85 ES-SCLC who received between January 2008 and June 2017 were retrospectively reviewed. Eligibility criteria biological...
To examine the thickness of ganglion cell-inner plexiform layer (GCIPL) in eyes with resolved macular edema (ME) non-ischemic central retinal vein occlusion (CRVO), applying spectral-domain optical coherence tomography (SD-OCT), and its relationship visual acuity.The retrospective observational case-control study included 30 CRVO patients ME (ME eyes) after treatment, without (non-ME eyes). The GCIPL thickness, peripapillary nerve fiber (pRNFL) (CMT) were measured on a SD-OCT scan. Linear...
<b>Introduction:</b> Mirtazapine is an antidepressant that acts by enhancing serotonergic and noradrenergic neurotransmission. This study aimed to evaluate mirtazapine pharmacokinetic data from Korean psychiatric patients identify the potential factors affecting its steady-state concentration. <b>Methods:</b> A total of 337 samples concentrations 188 adult outpatients were retrospectively evaluated. Serum measured high-performance liquid chromatography-tandem mass spectrometry....
Purpose: To report the early clinical outcomes of combining intensity‐modulated radiation therapy (IMRT) and proton (IMPT) in comparison with IMRT alone treating oropharynx cancer (OPC) patients. Materials Methods: The medical records 148 OPC patients were retrospectively reviewed, who underwent definitive radiotherapy (RT) concurrent systemic therapy, from January 2016 till December 2019 at Samsung Medical Center. During 5.5 weeks&rsquo; RT course, initial 16 (or 18) fractions delivered...
<sec> <title>BACKGROUND</title> Excessive muscle loss is an important prognostic factor in esophageal cancer patients undergoing neoadjuvant chemoradiotherapy (NACRT), as reported our previous research. </sec> <title>OBJECTIVE</title> In this pilot study, we prospectively tested the feasibility of a health coaching mobile app for preventing malnutrition and patient population. <title>METHODS</title> Between July 2019 May 2020, enrolled 38 male with scheduled NACRT. For 8 weeks from start...