A5100736614- Comparative Animal Anatomy Studies
- Animal Diversity and Health Studies
- Physiological and biochemical adaptations
- Pluripotent Stem Cells Research
- Environmental and Agricultural Sciences
- Plant Ecology and Soil Science
- Land Use and Ecosystem Services
- Remote Sensing and Land Use
- Meat and Animal Product Quality
- Plant Water Relations and Carbon Dynamics
- Climate variability and models
- Proteins in Food Systems
- Plant tissue culture and regeneration
- Remote Sensing in Agriculture
- Aquaculture disease management and microbiota
- Forest, Soil, and Plant Ecology in China
- 3D Printing in Biomedical Research
- Atmospheric and Environmental Gas Dynamics
- Rangeland Management and Livestock Ecology
- Wildlife Ecology and Conservation
- CRISPR and Genetic Engineering
- Congenital heart defects research
- MicroRNA in disease regulation
- Nerve injury and regeneration
- Neurogenesis and neuroplasticity mechanisms
Boston Children's Hospital
2021-2025
Lanzhou University
2015-2024
Institute of Genetics and Developmental Biology
2024
Ministry of Agriculture and Rural Affairs
2022-2024
Henan University
2020-2024
Qingdao University
2023
China Meteorological Administration
2022
Institute of Zoology
2014-2021
Capital Medical University
2020
Stomatology Hospital
2020
Global warming is one of the most common environmental challenges faced by cold-water fish farming. Heat stress seriously affects feeding, growth, immunity, and disease resistance fish. These changes are closely related to destruction intestinal barrier function, change microbiota, metabolic dysfunction. However, causal relationship between phenotypic effects heat as well functions unknown. In current study, optimal growth temperature (16°C) rainbow trout was used control group, while...
The major enteric RNA viruses in pigs include porcine epidemic diarrhoea virus (PEDV), transmissible gastroenteritis (TGEV), rotavirus A (PRV-A), kobuvirus (PKV), sapovirus (PSaV) and deltacoronavirus (PDCoV). For differential diagnosis, a multiplex RT-PCR method was established on the basis of N genes TGEV, PEDV PDCoV, VP7 gene PRV-A, polyprotein PKV PSaV. This could specifically detect PEDV, PSaV without cross-reaction to any other circulating Chinese pig farms. limit detection this as low...
Antisera were developed that specifically recognize orphanin FQ/nociceptin, the 17 amino acid peptide reported to be endogenous ligand for orphan opioid receptor. Immunocytochemical localizations in rat spinal cord demonstrated FQ /nociceptin-immunoreactivity (-ir) was abundant superficial dorsal horn, lateral nucleus and region central canal, areas also exhibit prominent enkephalin-and dynorphin-ir. Orphanin FQ/nociceptin-ir not affected by rhizotomy, indicating is produced rather than...
Newborn neurons migrate along the processes of radial glial cells (RGCs) to reach their final positions in cortex. Here, we visualized individual migrating and RGCs using utero electroporation. We show that branching is closely correlated spatiotemporally with distribution Reelin. Time-lapse imaging revealed leading gave rise increasingly more branches once growth cones contacted Reelin-containing marginal zone. This was accompanied by translocation nucleus gradual shortening process....
Derivation of osteoblast-like cells from human pluripotent stem (hPSCs) is a popular topic in bone tissue engineering. Although many improvements have been achieved, the low induction efficiency because spontaneous differentiation hampers their applications. To solve this problem, detailed understanding osteogenic process hPSCs urgently needed.Monolayer cultured embryonic and human-induced were differentiated commonly applied serum-containing medium for 35 days. In addition to traditional...
Global warming is one of the most common environmental challenges faced by cold-water fish farming. Intestinal barrier function, gut microbiota, and microbial metabolites are significantly altered under heat stress, posing serious obstacles to healthy artificial culture rainbow trout. However, molecular mechanisms underlying intestinal injury in trout stress remain unclear. In present study, optimal growth temperature for (16 °C) was used control group, maximum tolerated (24 which subjected...
Abstract In Alzheimer’s disease, perturbations of glutamate neurotransmission lead to synaptic dysfunction and synapse loss. Several studies have used transport inhibitors demonstrate that soluble oligomers amyloid-β induce by interrupting uptake mediated transporter 1, the major in brain. The cellular targets effects oligomers, including nature any interaction with remain ill-defined. We generated a conditional 1 knockout mouse investigate celltype specific functions 1. Field excitatory...
Abstract Objectives Ageing is a universal and gradual process of organ deterioration. Radiation induces oxidative stress in cells, which leads to genetic damage affects cell growth, differentiation senescence. Astragaloside (AS)-IV has antioxidative, anti-apoptotic anti-inflammatory properties. Methods To study the protective mechanism AS-IV on radiation-induced brain senescence, we constructed ageing model, using biochemical indicators, senescence-associated galactosidase (SA-β-gal)...
GLT-1, the major glutamate transporter in mammalian central nervous system, is expressed presynaptic terminals that use as a neurotransmitter, addition to astrocytes. It widely assumed homeostasis regulated primarily by transporters astrocytes, leaving function of GLT-1 neurons relatively unexplored. We generated conditional knockout (KO) mouse lines understand cell-specific functions GLT-1. found stimulus-evoked field extracellular postsynaptic potentials (fEPSPs) recorded CA1 region...
Gene transfer techniques have been developed previously for certain model rice ( Oryza sativa L.) cultivars, but problems persist in U.S. lines low transformation rates and vitro callus culture. Moreover, few studies evaluated traits such as herbicide resistance transgenic under field conditions. A rapid efficient method was production evaluation of herbicide‐resistant elite cultivars. Six were transformed glufosinate by particle bombardment mature seed‐derived embryogenic calli; confered...
(1) Background: As a halophytic species, Tamarix (Tamarix chinensis) can be used for saline soil rehabilitation in China. The reclamation and of depend on the water consumption plants. However, whether resources support construction vegetation is still unknown. (2) Methods: In this study, we measured transpiration (T) 3 years using sap flow evaporation (E) 1 year micro-lysimeter land. values 2016 2017 were estimated with crop coefficients obtained 2018. (3) Results: evapotranspiration (ET)...
As the global climate warms, more creatures are threatened by high temperatures, especially cold-water fish such as rainbow trout. Evidence has demonstrated that long noncoding RNAs (lncRNAs) play a pivotal role in regulating heat stress animals, but we have little understanding of this regulatory mechanism. The present study aimed to identify potential key lncRNAs involved acute lncRNA and mRNA expression profiles trout head kidney were analyzed via high-throughput RNA sequencing, which...
With multiple targets and low cytotoxicity, natural medicines can be used as potential neuroprotective agents. The increase in oxidative stress levels inflammatory responses the brain caused by radiation affects cognitive function neuronal structure, ultimately leads to abnormal changes neurogenesis, differentiation, apoptosis. Astragaloside Ⅳ (AS-Ⅳ), one of main active constituents astragalus, is known for its antioxidant, antihypertensive, antidiabetic, anti-infarction, anti-inflammatory,...
Six abomasums of yaks (Bos grunniens) were studied with gross dissection and histological methods.It was found that the mucosa yak abomasum covered simple columnar epithelium.There lots spiral folds (≥10) in fundic glandular area.The developed membrane lamina propria occupied by high density glands.According to morphological characteristics glands, divided into cardiac, gastric pyloric glands.Cardiac glands curved tubular intumescent bottom small cavity.Fundic or branched where chief,...