- Viral gastroenteritis research and epidemiology
- Antimicrobial Resistance in Staphylococcus
- Respiratory viral infections research
- Animal Virus Infections Studies
- Biosensors and Analytical Detection
- SARS-CoV-2 detection and testing
- Infective Endocarditis Diagnosis and Management
- Streptococcal Infections and Treatments
- Virus-based gene therapy research
- Oral microbiology and periodontitis research
- Infection Control and Ventilation
- Diphtheria, Corynebacterium, and Tetanus
- Emergency and Acute Care Studies
- Respiratory Support and Mechanisms
- Viral Infections and Immunology Research
- Skin Diseases and Diabetes
- Pediatric Urology and Nephrology Studies
- Bacterial Identification and Susceptibility Testing
- Bacterial biofilms and quorum sensing
- Antibiotic Resistance in Bacteria
- Neonatal Health and Biochemistry
- Antibiotic Use and Resistance
- Biochemical and Structural Characterization
- SARS-CoV-2 and COVID-19 Research
- Mycobacterium research and diagnosis
Sapporo Medical University
2016-2024
Miwa Hospital
2021
Japan Pediatric Society
2017
Abstract Human adenovirus (HAdV) infections present diverse clinical manifestations upon infecting individuals, with respiratory predominating in children. We surveyed pediatric hospitalizations due to HAdV across 18 hospitals Hokkaido Prefecture, Japan, from July 2019 March 2024, recording 473 admissions. While remained below five cases per week September 2023, a notable surge occurred late October weekly admissions peaking at 15−20 November December. There were dramatic shifts the age...
Many reports have reported a reduction in respiratory infectious diseases and gastroenteritis immediately after the coronavirus disease 2019 (COVID-19) pandemic, but data continuing into 2022 are very limited. We sought to understand current situation of various among children Japan as July improve public health post-COVID-19 era.We collected on hospitalized with 18 hospitals from June 2022.In total, 3417 patients were during study period. Respiratory syncytial virus decreased drastically...
Abstract Following the coronavirus disease 2019 (COVID‐19) outbreak in February 2020, incidences of various infectious diseases decreased notably Hokkaido Prefecture, Japan. However, Japan began gradually easing COVID‐19 infection control measures 2022. Here, we conducted a survey children hospitalized with human metapneumovirus (hMPV), influenza A and B, respiratory syncytial virus infections 18 hospitals across Japan, spanning from July to June 2023. From March 2020 2022 (28 months), only...
Panton-Valentine leukocidin (PVL)-positive methicillin-resistant Staphylococcus aureus (MRSA) occasionally causes severe invasive infections. A 10-year-old immunocompetent boy in Hokkaido, the northern main island of Japan, was admitted with acute osteomyelitis right ilium, complicated by septic thrombophlebitis common iliac vein and pulmonary embolism. As MRSA isolated from blood sputum samples patient, linezolid vancomycin were initially used for treatment, later clindamycin added based on...
Abstract Objectives The GeneSoC ® that launched recently enables the quantitative detection of target genes (in approximately 15 min) using microfluidic thermal cycling technology. Here, we compared diagnostic performance “GeneSoC SARS-CoV-2 N2 Detection Kit” (Kyorin assay) and conventional severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) assays to verify clinical usefulness Kyorin assay. Methods Two hundred samples (100 nasopharyngeal 100 saliva specimens) were collected from...
A methicillin-susceptible Staphylococcus aureus with Panton-Valentine leukocidin (PVL) genes was isolated from refractory breast abscesses of 12-year-old girl in Japan, and classified into ST88, spa-t1245 coa-IIIa. This strain harboured PVL phage ΦSa2usa, which is usually found ST8 community-acquired methicillin-resistant S. clone USA300.
The accuracy of nucleic acid amplification tests (NAATs) is affected by various factors; however, studies examining the factors affecting quantitative severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigen test (QAT) are limited.A total 347 nasopharyngeal samples were collected from patients with disease 2019 (COVID-19), and date onset was obtained electronic medical records. SARS-CoV-2 level measured using Lumipulse Presto Ag (Presto), while NAAT performed Ampdirect 2019-nCoV...
Raoultella planticola was previously considered an environmental organism in soil, water, and plants. However, several cases of human infection have recently been reported association with R. planticola, some which life-threatening. Most were adults reduced immunity, few children. To our knowledge, there only two urinary tract (UTI) caused by children, including one case cystitis. Here, we present the first UTI congenital anomalies kidney (CAKUT) a 4-month-old male infant. The patient...
ST121/agr-IV methicillin-susceptible Staphylococcus aureus was isolated from a patient of septic arthritis (synovial fluid, blood, skin and nasal cavity). Although the Panton-Valentine leukocidin (PVL) gene negative, this isolate harboured encoding variant bone sialoprotein-binding protein with shortened SD-repeat region.
Abstract The group A rotavirus (RVA) G3P[9] is a rare genotype isolated in humans and cats. We only one strain RVA/Human-wt/JPN/R11-035/2014/G3P[9] among 487 stool samples our surveillance of children with gastroenteritis Japan, during 2014–2015. R11-035 was from 2 year old girl presenting vomiting diarrhea who had daily contact She type histo-blood antigen, which reported to be related human P[9] infection. Full genome sequencing revealed that the AU-1-like constellations, except for NSP3...