A5047349330- Dental Health and Care Utilization
- Oral microbiology and periodontitis research
- Health, Nursing, Elderly Care
- Dental Research and COVID-19
- Fluoride Effects and Removal
- Dental Erosion and Treatment
- Health Education and Validation
- Bone and Dental Protein Studies
- Education during COVID-19 pandemic
- Healthcare during COVID-19 Pandemic
- Infant Nutrition and Health
- Youth, Drugs, and Violence
- dental development and anomalies
- Science and Education Research
- Salivary Gland Disorders and Functions
- Maternal and Neonatal Healthcare
- Healthcare Regulation
- Water Quality and Pollution Assessment
- Migration, Racism, and Human Rights
- Public Health in Brazil
- Child Nutrition and Water Access
- Dental Trauma and Treatments
- Environmental and biological studies
- Environmental Sustainability and Education
- Dental Radiography and Imaging
Pontifícia Universidade Católica do Paraná
2010-2024
Universidade Federal do Paraná
2013-2024
Universidade Estadual de Campinas (UNICAMP)
2003-2024
Methodist University of Piracicaba
2005
There is evidence for a genetic component in caries susceptibility, and studies humans have suggested that variation enamel formation genes may contribute to caries. For the present study, we used DNA samples collected from 1,831 individuals various population data sets. Single nucleotide polymorphism markers were genotyped selected (ameloblastin, amelogenin, enamelin, tuftelin, tuftelin interacting protein 11) influence formation. Allele genotype frequencies compared between groups with...
Since the effect of iron (Fe) on cariogenicity sucrose in humans is unexplored, this study assessed situ Fe co-crystallized with (Fe-sucrose) topically applied vitro acidogenicity, biochemical and microbiological composition dental biofilm formed vivo demineralization enamel. During two phases 14 days each, 16 volunteers wore palatal appliances containing blocks human enamel, which were submitted to four groups separate treatments: (1) water; (2) 20% sucrose; (3) (w/v) plus 18 µg Fe/ml, (4)...
OBJECTIVE: The present study evaluated the association between lactotransferrin (LTF) gene polymorphism (exon 2, A/G, Lys/Arg) and dental caries. MATERIAL AND METHODS: A convenience sample of 110 individuals, 12 years old, was divided into: group 1, 48 individuals without caries experience (DMFT=0), 62 subjects with (DMFT>1). DNA obtained from a mouthwash 3% glucose solution, followed by scrapping oral mucosa. After purification, polymerase chain reaction (PCR), single strand conformation...
During the COVID-19 pandemic, psychological suffering was intensified due to social isolation measures. This study aims investigate effects of Integrative Community Therapy (ICT) in online modality as a strategy promote mental health during pandemic Brazil. To this end, an intervention mixed design, observational and longitudinal, with pre-test at T0 post-test T1, conducted virtual environment ICT circles. The sample comprised 65 participants who answered three forms T1 containing questions...
Caries is a multifactorial disease and little still known about the host genetic factors influencing susceptibility. Our previous genome-wide linkage scan has identified interval 5q12.1–5q13.3 as linked to low caries susceptibility in Filipino families. Here we fine-mapped this region order identify contributors Four hundred seventy-seven subjects from 72 pedigrees with similar cultural behavioral habits limited access dental care living Philippines were studied. DMFT scores genotype data of...
The aim of this study was to evaluate whether genetic polymorphisms in <i>AMELX</i>,<i> AMBN</i>,<i> ENAM</i>,<i> TFIP11</i>, and<i> TUFT1</i> genes are associated with dental fluorosis (DF). A total 1,017 children from 2 Brazilian cohorts were evaluated. These populations lived cities fluoridation public water supplies. DF assessed erupted permanent teeth using the modified Dean index. rs946252, rs12640848, rs4694075, rs5997096,...
Regarding host aspects, there has been strong evidence for a genetic component in the etiology of caries. The salivary protein lactotransferrin (LTF) exhibits antibacterial activity, but is no study investigating association polymorphisms promoter region LTF gene with objective this was firstly to search human variations and, if existent, investigate identified dental caries 12-year-old students. From 687 unrelated, 12-year-old, both sex students, 50 individuals were selected and divided...
Saliva components play a crucial role in the integrity of dental enamel and caries susceptibility. The saliva characteristics are controlled by many factors, including genetic factors. Therefore, this study aimed to evaluate association between variations genes expressed development with calcium phosphorus levels saliva. We collected 276 unrelated 12-year-old children from private public schools. was for DNA extraction oral cells measurement phosphorus. Inductively coupled plasma-mass...
This study evaluated the effect of sealants on enamel demineralization, focusing physical protection sealed and fluoride adjacent unsealed enamel. Occlusal fissures with areas measuring 12 mm2 were delimited in 48 extracted molars, randomly divided into 4 groups (n =12): 1) no sealing; 2) sealing a resin-modified glass-ionomer (Vitremer™, 3M ESPE); 3) fluoride-releasing composite sealant (Clinpro Sealant™, 4) non-fluoridated (Concise™, ESPE). A 4-mm2 window was outlined buccal for analysis...
Este estudo apresenta dados de cárie dentária e fluorose em sete municípios representativos da região Sorocaba, São Paulo, Brasil, que possuem ou não flúor nas águas abastecimento público. A metodologia utilizada foi proposta pela Organização Mundial Saúde (WHO, 1997), adaptada Faculdade Pública Universidade Paulo. amostra probabilística, admitindo um erro desenho 2 perda amostral 20,0% (n = 96 por idade). Foram calibrados seis examinadores, com porcentagem concordância acima 89% para as...
Dental caries is a common multifactorial disease, resulting from the interaction of biofilm, cariogenic diet and host response over time. Lactotransferrin (LTF) main salivary glycoprotein, which modulates immune-inflammatory antibacterial response. Although genetic component for outcome has been identified, little known aspects underlying its susceptibility. Thus, aim this study was to investigate association between <i>LTF</i> polymorphisms Six hundred seventy seven 12-year-old...
The aim of this study is to evaluate the association between single nucleotide polymorphism (SNP) rs4284505 within gene that codifies microRNA17 (miRNA17) and dental fluorosis (DF) in a group children.Children living city with fluoridation public water supplies were included. DF was assessed erupted permanent teeth by Dean's modified index. miR-SNP selected miRNA17 genotyping carried out real-time PCR. Genotype allelic distributions control, phenotypes (mild, moderate severe) control...
O PET-Saúde veio consolidar as parcerias entre aUFPR e Secretarias Municipais de Saúde Colombo Curitiba. Essa integração conta ainda com a participação dos Programas Residências da UFPR: Multiprofissional em Família Medicina Comunidade no município Colombo. As atividades têm por objetivo formação um profissional visão integral do processo saúde-doença prática humanizada assistência à saúde individual coletiva. Os acadêmicos bolsistas/voluntários PET-Saúde, sob orientação acompanhamento...
Dental caries is one of the most prevalent diseases around world and saliva plays an essential role in controlling evolution disease. This study aimed to investigate if salivary pH correlated with dental a population Brazilian adolescents. Adolescents, both sexes, were submitted clinical examinations for diagnosis according Decay, Missing, Filling Teeth index (DMFT). The adolescents allocated into two groups: i. unaffected by (DMFT= 0) ii. affected (DMFT≥ 1). Saliva samples collected, was...
The purpose of the study was to investigate association between single nucleotide polymorphisms (SNPs) in genes encoding estrogen receptors (ESR1 and ESR2, respectively) delayed tooth emergence (DTE). This cross-sectional composed biological unrelated children both sexes, age ranging from 11 13 years old. DTE defined when successor primary still present oral cavity after its exfoliation time or absence permanent into cavity. Children were diagnosed with they had at least one tooth, according...
Homeostasis between salivary calcium and phosphorus is important for maintaining oral health. The aim of this study was to evaluate if polymorphisms in ESR1 (Estrogen Receptor Alpha), ESR2 Beta) miRNA17 (microRNA17) are associated with levels saliva. Saliva from 276 12-year-old children were collected by masticatory stimulation determined Mass Spectrometry. Genomic DNA extracted remaining saliva genetic (rs12154178, rs1884051, rs9340799 rs2234693), (rs4986938 rs1256049) (rs4284505) genotyped...
RESUMO O objetivo deste estudo transversal foi identificar adequações quanto à utilização de Equipamentos Proteção Individual e organização do processo trabalho no atendimento odontológico ambulatorial Paraná durante o primeiro ano da pandemia Covid-19. A amostra conveniência incluiu 1.105 profissionais saúde bucal (cirurgiões-dentistas, técnicos auxiliares em bucal) (agosto a outubro 2020). Formulário on-line (Google Formulários®) enviado por e-mail pelo Conselho Regional Odontologia. As...
Analisar os resultados das amostras do Programa de Vigilância da Qualidade Água para o Consumo Humano (VIGIAGUA) parâmetro fluoreto, na água abastecimento público cidade Araucária, PR, Brasil. Material e métodos: Os 95 ano 2018 foram disponibilizados pela Ambiental estado Paraná, as quais classificadas por dois critérios: I [4] II [10]. Após a classificação, realizou-se análise descritiva, com expressão valores mínimo, máximo, média desvio-padrão cada mês. Resultados: A maior concentração...
Background/Objectives: Identify the factors associated with participation in Integrative Community Therapy (ICT) circles Brazil, focusing on socio economic profile, health status, usage of other Traditional, Complementary, and Medicines (TCIM), mental disorders, support from family friends. Methods: Data 2019 National Health Survey Brazil (NHS) were used, which, 94,114 people interviewed, 5649 answered question regarding ICT circles, 93 affirmative answers. A paired case-control study was...
Objetivo: Descrever o perfil dos acidentes com material biológico notificados no Sistema de Informação Agravos Notificação, durante período 2012 a 2016, acadêmicos Odontologia, em um município do sul Brasil e verificar se há divergências entre os registros da Comissão Controle Infecção Odontológica uma instituição Informação. Materiais Métodos: Estudo observacional descritivo. Para identificação curso estudante, realizou-se busca complementar nas fichas notificação localização nominal sítios...