A5101952467- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- RNA modifications and cancer
- Spine and Intervertebral Disc Pathology
- Orthopaedic implants and arthroplasty
- Parasites and Host Interactions
- Helminth infection and control
- Hip disorders and treatments
- Parasite Biology and Host Interactions
First Hospital of Shanxi Medical University
2020-2025
Shanxi Medical University
2020-2025
Wenzhou Medical University
2021-2022
Taizhou First People's Hospital
2019-2022
Yangzhou University
2021
South China Agricultural University
2019
Laryngeal squamous cell carcinoma (LSCC) is the second most common malignant tumor in head and neck. Autophagy circular RNAs (circRNAs) play critical roles cancer progression chemoresistance. However, function mechanism of circRNA autophagy regulation LSCC remain unclear. The autophagy-suppressive circPARD3 was identified via RNA sequencing 107 tissues paired adjacent normal mucosal (ANM) high-content screening. RT-PCR, Sanger sequencing, qPCR fluorescence situ hybridization were performed...
Head and neck squamous cell carcinoma (HNSCC), a highly invasive malignancy with poor prognosis, is one of the most common cancers globally. Circular RNAs (circRNAs) have become key regulators human malignancies, but further studies are necessary to fully understand their functions possible causes in HNSCC. CircCCT2 expression levels HNSCC tissues cells were measured via qPCR. was characterized by Sanger sequencing, qRT-PCR, RNase R & Actinomycin D treatment, nucleoplasmic separation FISH...
Background: Numerous studies have recorded the function of long noncoding RNAs (lncRNAs) in cancer development, including lung adenocarcinoma (LUAD). Previous reported crucial role lncRNA PTPRG antisense RNA 1 (PTPRG-AS1) various cancers. However, PTPRG-AS1 LUAD remains unknown. Materials and Methods: Real-time quantitative polymerase chain reaction (RT-qPCR) was applied for detecting expression cell lines. Functional assays vivo experiments explored proliferation, whereas flow cytometry...
Melting temperature shift (Tm-shift) is a new detection method that analyze the melting curve on real-time PCR thermocycler using SYBR Green I fluorescent dye. To establish Tm-shift for of Ancylostoma ceylanicum and A. tubaeforme in cats, specific primers, with GC tail unequal length attached to their 5′ end, were designed based 2 SNP loci (ITS101 ITS296) internal transcribed spacer 1 (ITS1) sequences. The standard was established plasmids (AceP) (AtuP). stability, sensitivity, accuracy...
<b><i>Introduction:</i></b> Bladder cancer (BC) is a common malignant tumor in the urinary system with high mortality and recurrence rates. This study sought to identify crucial circular RNAs (circRNAs) associated BC. <b><i>Methods:</i></b> The mRNA, miRNA, circRNA expression profiles of BC were downloaded from GEO database. differentially expressed mRNAs (DEmRNAs), miRNAs (DEmiRNAs), circRNAs (DEcircRNAs) identified using bioinformatics...
Little is known about the anatomical changes in lumbosacral vertebrae and their correlation with facet joint-derived low back pain patients hip osteoarthritis (HOA) after total arthroplasty.