A5087668721- Ferroptosis and cancer prognosis
- MicroRNA in disease regulation
- Extracellular vesicles in disease
- RNA modifications and cancer
- Caveolin-1 and cellular processes
- Cancer, Lipids, and Metabolism
- Ureteral procedures and complications
- Glioma Diagnosis and Treatment
- Prostate Cancer Diagnosis and Treatment
- Bladder and Urothelial Cancer Treatments
- Pelvic floor disorders treatments
- Central Venous Catheters and Hemodialysis
- Fungal Infections and Studies
- CAR-T cell therapy research
- Anorectal Disease Treatments and Outcomes
- Blood properties and coagulation
- Acupuncture Treatment Research Studies
- Neuroendocrine regulation and behavior
- Renal cell carcinoma treatment
- Platelet Disorders and Treatments
- MRI in cancer diagnosis
- Cytomegalovirus and herpesvirus research
- Protein purification and stability
- Travel-related health issues
- Acute Kidney Injury Research
Nanfang Hospital
2023-2024
Southern Medical University
2023-2024
Capital Medical University
2024
Fujian Medical University
2024
Fuzhou University
2024
Shanghai Children's Hospital
2010-2023
Shanghai Jiao Tong University
2017-2023
Fourth People’s Hospital of Jinan
2017
Wuhan University
2010-2015
Renmin Hospital of Wuhan University
2010-2015
Temozolomide resistance remains a major obstacle in the treatment of glioblastoma (GBM). The combination temozolomide with another agent could offer an improved option if it overcome chemoresistance and prevent side effects. Here, we determined critical drug that cause ferroptosis GBM cells elucidated possible mechanism by which overcomes chemoresistance.Haloperidol/temozolomide synergism was assessed cell lines different dopamine D2 receptor (DRD2) expression vitro vivo. Inhibitors...
Previous studies demonstrated inhibitory effects of nitric oxide (NO) and cGMP on ovarian steroidogenesis. This study examined the NO estrogen levels cAMP accumulation from immature cultured rat granulosa cells. Granulosa cells were incubated with media alone (control), FSH or plus increasing concentrations generator, (Z)-1-[2-(2-aminoethyl)-N-(2-ammonioethyl)amino]diazen-1-ium-1,2-diolate (DETA/NO). While increased 15-fold compared controls, DETA/NO inhibited FSH-stimulated aromatase...
Background: This study aimed to examine the epidemiological characteristics of imported infections and assess effectiveness border health screening in detecting diseases. Methods: We obtained infection data for 2016 2019 from Fuzhou Changle International Airport Infection Reporting System. The demographic, temporal, spatial travel-related were analyzed using r×c contingency tables, Cochran–Armitage trend test, seasonal-trend decomposition LOESS (STL). Detection rates used as a proxy...
Pemetrexed, a new and novel agent for primary central nervous system lymphomas (PCNSLs), has shown to be efficient as savage therapy recurrent PCNSLs. However, more studies are needed. A prospective study was performed on 17 PCNSL patients with pemetrexed at Shandong Tumor Hospital in China assess the efficacy safety of patients.The medical records imaging data all cases our were collected during August 2012 April 2015. Folic acid, B12, dexamethasone used induce toxicities related...
Purpose: We report a case of hyperthyroidism in young woman caused by Graves’ disease that was successfully treated with thyroid arterial embolization. Clinical details: A 35 year-old history thyrotoxic crises admitted after the last crisis. Thyroid embolization used to treat it had been controlled. Immediately embolization, enlarged gland shrank and vascular murmurs disappeared. Serum hormones increased on day 3 following but decreased gradually. hormone returned normal 2 months remained at...
Zellweger spectrum disorder (ZSD) is a heterogeneous group of autosomal recessive disorders characterized by defect in peroxisome formation and attributable to mutations the PEX gene family. Patients with ZSD have profound neurologic impairments, including seizures, severe retardation, dysmorphic features, poor prognosis. Currently, there no specific, effective treatment. Here, we investigated effects allogeneic hematopoietic stem cell transplantation (allo-HSCT) on PEX1 -related ZSD. The...
<p>Fig. S3. HP radiosensitive GBM cells.</p>
<p>Fig. S1. HP does not trigger apoptosis in GBM cells.</p>
<p>Fig. S4. Autophagy, endoplasmic reticulum stress and cAMP pathway are involved in TMZ+HP-induced ferroptosis GBM cells.</p>
<p>Fig. S2. TMZ+HP Hp induces ferroptosis in GBM cells.</p>
<p>Fig. S3. HP radiosensitive GBM cells.</p>
<p>Fig. S2. TMZ+HP Hp induces ferroptosis in GBM cells.</p>
<div>Abstract<p>Purpose:Temozolomide (TMZ) resistance remains a major obstacle in the treatment of glioblastoma (GBM). The combination TMZ with another agent could offer an improved option if it overcome chemoresistance and prevent side effects. Here, we determined critical drug that cause ferroptosis GBM cells elucidated possible mechanism by which overcomes chemoresistance. Experimental Design:Haloperidol/TMZ synergism was assessed cell lines different DRD2 expression...
<div>Abstract<p>Purpose:Temozolomide (TMZ) resistance remains a major obstacle in the treatment of glioblastoma (GBM). The combination TMZ with another agent could offer an improved option if it overcome chemoresistance and prevent side effects. Here, we determined critical drug that cause ferroptosis GBM cells elucidated possible mechanism by which overcomes chemoresistance. Experimental Design:Haloperidol/TMZ synergism was assessed cell lines different DRD2 expression...
<p>Fig. S2. TMZ+HP Hp induces ferroptosis in GBM cells.</p>
<p>Fig. S3. HP radiosensitive GBM cells.</p>
<p>Fig. S4. Autophagy, endoplasmic reticulum stress and cAMP pathway are involved in TMZ+HP-induced ferroptosis GBM cells.</p>
<p>Fig. S1. HP does not trigger apoptosis in GBM cells.</p>
<p>Fig. S4. Autophagy, endoplasmic reticulum stress and cAMP pathway are involved in TMZ+HP-induced ferroptosis GBM cells.</p>
<p>Fig. S1. HP does not trigger apoptosis in GBM cells.</p>
<p>Fig. S4. Autophagy, endoplasmic reticulum stress and cAMP pathway are involved in TMZ+HP-induced ferroptosis GBM cells.</p>