- Genomics and Phylogenetic Studies
- Genetic diversity and population structure
- Neuroscience and Neural Engineering
- Antimicrobial Peptides and Activities
- Attention Deficit Hyperactivity Disorder
- Plant nutrient uptake and metabolism
- Collaborative and Sustainable Housing Initiatives
- Developmental Biology and Gene Regulation
- Postharvest Quality and Shelf Life Management
- Immune Response and Inflammation
- RNA and protein synthesis mechanisms
- Protist diversity and phylogeny
- Neuroinflammation and Neurodegeneration Mechanisms
- Phytochemicals and Antioxidant Activities
- Spatial Cognition and Navigation
- Plant and animal studies
- Bacteriophages and microbial interactions
- Plant Molecular Biology Research
- Urban Planning and Valuation
- Genetics, Aging, and Longevity in Model Organisms
- Plant Gene Expression Analysis
- Optical Network Technologies
- Plant Diversity and Evolution
- Ecology and Vegetation Dynamics Studies
- Barrier Structure and Function Studies
Chinese Institute for Brain Research
2021-2024
South China University of Technology
2020-2024
Qingdao Agricultural University
2023-2024
University of Reading
2023
Cardiff Metropolitan University
2023
Central South University
2022
Guangzhou Medical University
2020
Guangzhou First People's Hospital
2020
The fundamental differences in phospholipids between bacterial and mammalian cell membranes present remarkable opportunities for antimicrobial design. However, it is challenging to distinguish anionic phospholipid phosphatidylglycerol (PG) from phosphatidylserine (PS) with the same net charge. Here, we report a class of radially amphiphilic α helix peptides (RAPs) that can selectively discriminate PG PS, relying on structure. representative RAP, L
Leaf senescence is the terminal stage of leaf development, and its initiation progression are closely controlled by integration a myriad endogenous signals environmental stimuli. It has been documented that WRKY transcription factors (TFs) play essential roles in regulating senescence, yet molecular mechanism WRKY-mediated still lacks detailed elucidation crop plants. In this study, we cloned identified tobacco TF gene, designated NtWRKY70b, acting as positive regulator natural senescence....
Leaf senescence is a comprehensive process performed by integrating various internal and external signals, followed nutrient reallocation, especially via organic nitrogen (e.g., amino acids) mobilization. Amino acid (AA) transporters play an important role in crop growth development participating the of remobilization. However, biological functions downstream effectors involved leaf are still poorly understood. In present study, we cloned characterized cationic transporter gene, NtCAT1, from...
Abstract The stimulant methylphenidate (MPH) and the non-stimulant atomoxetine (ATX) are frequently used for treatment of attention-deficit/hyperactivity disorder (ADHD); however, function these drugs in different types brain cells their effects on related genes remain largely unknown. To address questions, we built a pipeline simultaneous examination activity behavior transcriptional responses Drosophila melanogaster at single-cell resolution following drug treatment. We selected with...
Due to the difficulty in accurately identifying structural variants (SVs) across genomes, their impact on cis-regulatory divergence of closely related species, especially fish, remains be explored. Recently identified broad H3K4me3 domains are essential for regulation genes involved several biological processes. However, role phenotypic poorly understood. Siniperca chuatsi and S. scherzeri but divergent traits, making them an ideal model study evolution sister species. Here, we generated...
Abstract The subcommissural organ (SCO) is a gland located at the entrance of aqueduct Sylvius in brain. It exists species as distantly related amphioxus and humans, but its function largely unknown. To explore function, we compared transcriptomes SCO non-SCO brain regions found three genes, Sspo , Car3 Spdef that are highly expressed SCO. Mouse strains expressing Cre recombinase from endogenous promoter/enhancer elements these genes were used to genetically ablate cells during embryonic...
. A correlation analysis was constructed according to the effect of catalyst and temperature on chemical reaction in ethanol coupling C4 olefin. Firstly, relationship between product, temperature, product explored. The mechanism qualitative image inferred that is related conversion olefin selectivity. Then Pearson coefficients each group temperatures corresponding experimental data are calculated, 90% greater than 0.9. it confirmed they have a significant positive correlation.
<title>Abstract</title> The stimulant methylphenidate (MPH) and the non-stimulant atomoxetine (ATX) are frequently used for treatment of attention-deficit/hyperactivity disorder (ADHD); however, function these drugs in different types brain cells their effect on related genes remain largely unknown. To address questions, we built a pipeline simultaneous examination activity behavior transcriptional responses <italic>Drosophila melanogaster</italic> at single-cell resolution following drug...
Abstract Background Dissecting the genetic basis of variation in regulation gene expression is essential for understanding phenotypic evolution. Structural variants intersecting cis -regulatory elements are found to cause several developmental genes, resulting morphological divergence between species. Due difficulty identifying structural accurately across genome, a comprehensive study impacts closely related species, especially fish still scarce. Recently identified broad H3K4me3 domains...
Leaf mimicry is a fascinating phenomenon in nature. Among the widespread leaf mimics, Kallima butterflies display cryptic dead leaf-like wing patterns and have served as classic case of protective resemblance supporting theory natural selection. Here, we integrated multi-omics data analyses functional validation to uncover evolutionary history investigated genetic basis their mimicry. We found evidence for differentiation radiation from Eastern Himalaya East Asia Southeast Asia. Moreover,...