A5039202140- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Radioactive element chemistry and processing
- Radiopharmaceutical Chemistry and Applications
- Medical Imaging Techniques and Applications
- Boron Compounds in Chemistry
- Lanthanide and Transition Metal Complexes
- Radiation Detection and Scintillator Technologies
- Organometallic Complex Synthesis and Catalysis
- Luminescence Properties of Advanced Materials
- Nuclear Physics and Applications
- Plant Micronutrient Interactions and Effects
- Orthopaedic implants and arthroplasty
- Nuclear materials and radiation effects
- Plant Stress Responses and Tolerance
- Plant nutrient uptake and metabolism
- Peptidase Inhibition and Analysis
- Crystallography and molecular interactions
Oak Ridge National Laboratory
2019-2020
Oak Ridge Associated Universities
2020
University of Missouri
2015-2018
Harry S. Truman Memorial Veterans' Hospital
2016
Abstract The OLIGOPEPTIDE TRANSPORTER 3 (OPT3) has recently been identified as a component of the systemic network mediating iron (Fe) deficiency responses in Arabidopsis. Reduced expression OPT3 induces an over accumulation Fe roots and leaves, due part by elevated IRON‐REGULATED 1. Here we show however, that opt3 leaves display transcriptional program consistent with overload, suggesting excess is properly sensed OPT3‐mediated shoot‐to‐root signaling critical to prevent overload. We also...
Gadolinium vanadate (GdVO4) core and + 2 shell nanocrystals (NCs) were evaluated for in vitro retention of 225Ac, 227Th, their first decay daughters, 221Fr 223Ra, respectively. GdVO4 NCs with a tetragonal crystal system (zircon-type) spherical morphology obtained by precipitation GdCl3 Na3VO4 using sodium citrate as complexing agent. The growth two nonradioactive shells on both Gd(225Ac)VO4 Gd(227Th)VO4 was demonstrated an increase 0.7 nm the crystallite size, maximum leakage 225Ac 15% 2.4%...
Abstract To explore the coordination chemistry of salicylaldiminate ligands as a non‐cyclopentadienyl ligand framework, we report synthesis their Th IV and U complexes. Deprotonation (NC 5 H 4 )N=C(H)(3,5‐ t Bu 2 C 6 )OH ( 1 ), 9 (CH 3 SC ) with sodium hydride subsequent addition 0.5 equivalents [UI (1,4‐dioxane) ] yielded [{(NC )O‐κ O , N N′ )} UI [{(CH S respectively. The reaction salt afforded U]I 7 ). By using [ThCl (dme) ], ThCl 8 were isolated. metathesis both chloride in NaN led to...
La(<sup>227</sup>Th)PO<sub>4</sub>core +2 shells nanoparticles retained >99.75% of activity from<sup>227</sup>Th and decay daughters (<sup>223</sup>Ra,<sup>211</sup>Pb) for targeted alpha therapy.
Abstract Unwanted targeting of healthy organs caused by the relocation radionuclides from target site has been one limiting factors in widespread application targeted alpha therapy patient regimens. GdVO 4 nanoparticles (NPs) were developed as platforms to encapsulate α -emitting 223 Ra, 225 Ac, and 227 Th, retain their decay daughters at site. Polycrystalline NPs with different morphologies a zircon-type tetragonal crystal structure obtained precipitation GdCl 3 Na VO aqueous media room...
We report the synthesis and spectroscopy of pseudo-halide complexes uranyl coordinated to salicylaldiminate ligands. The reaction [(NC9H6)N=C(H)C6H2tBu2O-κ3(O,N,N′)]UO2Cl(THF), 1, with NaN3 produces a rare example an azide, [(NC9H6)N=C(H)C6H2tBu2O-κ3(O,N,N′)]UO2(N3)(THF), 2. A series isocyanates, [(NC9H6)N=C(H)C6H2tBu2O-κ3(O,N,N′)]UO2(NCE)(THF), E = O, 3; S, 4; Se, 5, were synthesized from 1 KNCE. Reaction AgNO3 AgOTf (OTf SO3CF3) [(NC9H6)N=C(H)C6H2tBu2O-κ3(O,N,N′)]UO2(NO3), 6...
We report the synthesis and structural determination of three uranium(IV) complexes bearing two, four, six salicylaldiminate ligands. Reaction UI4(1,4-dioxane)2 with equivalents K[OC6H4C(H)=N(2,6-iPr2C6H3)], 1, yielded [(2,6-iPr2C6H3)N=C(H)C6H4O-κ2(O,N)]2UI2(NCCH3), 2, [(2,6-iPr2C6H3)N=C(H)C6H4O-κ1(O)]2[(2,6-iPr2C6H3)N=C(H)C6H4O-κ2(O,N)]2U(THF), 3, {[2,6-iPr2C6H3)N=C(H)C6H4O-κ1(O)]6U}2−, 4. While 2 shows normal κ2-coordination through both oxygen nitrogen donors, 3 has two ligands bound only...