Laparoscopy has revolutionized many abdominal surgical procedures. Laparoscopic colectomy become increasingly popular. The short- and long-term benefits satisfactory oncological treatment of colorectal cancer by laparoscopic-assisted resection remain topical. outcomes all international randomized controlled trials are still awaited, short-term important in the interim.Between January 1998 April 2005, a multicenter, prospective, clinical trial patients with colon was conducted. Six hundred...

In Brief Objective: We report a multicentered randomized controlled trial across Australia and New Zealand comparing laparoscopic-assisted colon resection (LCR) with open (OCR) for cancer. Background: Colon cancer is significant worldwide health issue. This investigated whether the short-term benefits associated LCR could be achieved safely, without survival disadvantages, in our region. Methods: A total of 601 patients potentially curable were to receive or OCR. Primary endpoints 5-year...

Helicobacter pylori infection in humans is associated with diverse of clinical outcomes which are partly attributed to bacterial strain differences. Secreted products thought be involved the pathogenesis caused by this non-invasive bacterium. Electron microscopy gastric biopsies from infected individuals revealed blebbing H. outer membrane, similar process membrane vesicle shedding occurs when bacterium grown broth. Porins, a class proinflammatory proteins, were observed vesicles. The VacA...

Helicobacter pylori infection of the stomach is accompanied by a persistent polymorphonuclear leukocyte (PMNL) infiltrate mucosa. The aim this work was to study activation human PMNL substances produced H pylori. Filtered conditioned media stimulated significant oxidative burst (p less than 0.002). This equal 26% maximal response chemotactic peptide N-formyl-methionyl-leucyl-phenylalanine (FMLP, 1 mumol/l). FMLP prolonged combined presence complement inactivated anti-H plasma and medium High...

PURPOSE: A clinically relevant, laparoscopic colectomy model has been developed to quantify surgical practices that may affect the incidence of port wound tumor implantation. METHODS: Suspended51Cr-labeled, fixed HeLa cells were injected intraperitoneally into pigs before colectomies performed with or without insufflation. Tumor cell contamination instruments, ports, stability threads, and excised margins was determined by gamma counting. RESULTS: distributed throughout peritoneal cavity,...

This study reports the quality-of-life assessment of ALCCaS trial. The trial compared laparoscopic and open resection for colon cancer. It reported equivalence survival at 5 years. Quality life was measured as a secondary outcome.This aimed to report on quality data Trial.This randomized controlled comparing with colonic resection.The conducted in Australasia.Patients single adenocarcinoma right, left, or sigmoid colon, presenting elective treatment, were eligible randomization.Open...

BACKGROUND: An increased risk of laparoscopic port wound tumor implantation in the presence overt or covert abdominal malignancy has been identified. PURPOSE: A porcine colectomy model used to quantify influence surgical practices may have on cell implantation. METHODS: 51Cr-labeled, fixed HeLa cells were injected intraperitoneally before surgery. Tumor contamination instruments, ports, security threads, and excised margins was assessed by gamma counting. RESULTS: Greatest occurred ports...

Abstract Background A retrospective analysis of age-related postoperative morbidity in the Australia and New Zealand prospective randomized controlled trial comparing laparoscopic open resection for right- left-sided colonic cancer is presented. Methods total 592 eligible patients were entered studied from 1998 to 2005. Results Data 294 who underwent 298 had analysed; 266 aged less than 70 years 326 or older (mean(s.d.) 70·3(11·0) years). Forty-three operations (14·6 per cent) converted an...

The temporal relationship of changes in atrial natriuretic peptide (ANP) secretion to other pathophysiological heart failure has not been investigated. We studied the hemodynamic, hormonal, and metabolic before, during, after induction eight sheep using a 14-day period rapid left ventricular pacing (LVP). Arterial pressure declined 21% on first day, while cardiac output fell progressively 48% base line, pressures rose plateau over week. Plasma ANP levels increased 10-fold with close...

A randomized trial of routine circumcision in children using the Plastibell device is described and compared to a dissection suturing technique. One hundred were studied with mean age 4.7 years. The was applicable all boys up 8, few older. General discomfort carefully assessed slightly less common after plastibell circumcision, but dysuria more so. No serious complication encountered either method; infection conventional procedure. Cosmetic results similar for both methods. It concluded that...

Background: Diaphragmatic hernias complicating pregnancy are not a common problem but they can have catastrophic consequences. They present to the surgeon as life‐threatening emergency or pose management dilemma when detected incidentally. In this paper, recommendations for of non‐hiatal maternal diaphragmatic made based on our experience and available published reports. Methods: The presentation, outcomes series three recent cases described. A review all other reported was also carried out....

The urease inhibitor acetohydroxamic acid (AHA) was assessed for its bacteriostatic and bactericidal effects on Helicobacter pylori. For eight isolates of H pylori, the minimum inhibitory concentration (MIC) either 200 mg/l or 400 mg/l. Interactions between AHA antimicrobial drugs used to treat pylori were also determined. most reduced MIC colloidal bismuth subcitrate (CBS), tetracycline, metronidazole, amoxicillin. In a few isolates, however, increased (MBC) these treatments. vitro is...

The iron content of human nails has been measured by atomic absorption spectrophotometry and compared with other measurements status including the bone marrow. Four groups individuals were studied: 40 healthy laboratory staff, five iron-deficient subjects before during therapy, four patients at various stages treatment iron, 15 postmortem cases. individual was reflected amount present in nail samples. Nail sampling is proposed as a cheap, noninvasive method assessing individual.

Background: Surgical resection has been the standard treatment for duodenal adenomas. It a high associated morbidity rate and significant recurrence rate. The aim of this study was to evaluate endoscopic these lesions with argon plasma coagulation. Methods: We retrospectively identified patients non‐ampullary adenomas without polyposis syndrome who were treated endoscopically between 1st January 1999 31st December 2003. Their management, follow up outcomes reviewed. Results: Fifteen...

This article describes the initiation and implementation of multicentre Australia New Zealand prospective randomized controlled clinical study comparing laparoscopic conventional open surgical treatments right-sided left-sided potentially curable colon cancer (Australasian Laparoscopic Colon Cancer Study). Six hundred one adult patients were admitted with a diagnosis single adenocarcinoma based on physical examination colonoscopy, barium enema or computed tomography scan randomly allocated...