- Musculoskeletal pain and rehabilitation
- Nutrition and Health in Aging
- Asthma and respiratory diseases
- Bone and Joint Diseases
- Spine and Intervertebral Disc Pathology
- Meningioma and schwannoma management
- Hip and Femur Fractures
- Respiratory and Cough-Related Research
- Neonatal Respiratory Health Research
- Scoliosis diagnosis and treatment
- Pediatric health and respiratory diseases
- Frailty in Older Adults
- Neurofibromatosis and Schwannoma Cases
- Gallbladder and Bile Duct Disorders
- Bone health and osteoporosis research
- Occupational Health and Performance
- Pancreatic and Hepatic Oncology Research
- Electrical and Bioimpedance Tomography
- Spinal Hematomas and Complications
- Cerebral Palsy and Movement Disorders
- Thermoregulation and physiological responses
- Thermal Regulation in Medicine
- Vascular Malformations Diagnosis and Treatment
- Climate Change and Health Impacts
- Inflammatory Biomarkers in Disease Prognosis
The University of Tokyo
2024-2025
University of Tokyo Health Sciences
2024-2025
Jichi Medical University
2024
National Center for Geriatrics and Gerontology
2017-2024
Gunma University
2019
Nagoya University
2012
The prevalence of chronic low back pain (CLBP) increases with age and several mechanisms are involved in the development CLBP, including osteoporosis; however, no associations sarcopenia have yet been identified.In total, 100 patients CLBP 560 without (nCLBP) aged over 65 years were studied. Skeletal muscle mass index (SMI) percentage body fat evaluated using whole-body dual-energy X-ray absorptiometry. Sarcopenia was diagnosed when relative SMI more than 2 standard deviations below mean...
Abstract Heat-related diseases have become a significant public health concern. Studies shown that susceptibility to heat varies among regions; however, most studies used aggregated data on emergency transport in the regions. The present study nationwide inpatient database Japan and examined association between regional differences Wet Bulb Globe Temperature (WBGT) in-hospital mortality patients with heat-related disease, adjustment for individual-level characteristics. We retrospectively...
Abstract Background Opioids are often administered for extremely preterm infants to prevent morbidities (e.g., intraventricular hemorrhage); however, their short-term outcome remains unclear. We aimed assess the association between early-phase opioid use and in-hospital outcomes in infants. Methods This retrospective nationwide cohort study analyzed data from Diagnosis Procedure Combination database Japan. A total of 18,794 hospitalized July 2010 March 2021 were included. The patients...
Background The 2014 European Respiratory Society/American Thoracic Society guidelines defined severe asthma based on treatment intensity and estimated the proportion of among all cases to be 5–10%. However, data supporting estimate comprehensive sequential are scarce. We aimed national prevalence during last decade. Methods Using a Japanese administrative database, which covers ≥99% population, we evaluated in 2013, 2015, 2017 2019. Additionally, elucidated demographic characteristics,...
Abstract Background Although sarcopenia has been known as a risk factor for hip fracture, only few reports have described the impact of muscle mass on fracture treatment outcomes. The current study aimed to investigate Methods This case–control involved 337 patients (67 males and 270 females) with aged ≥65 years (mean age: 84.1 ± 7.1 years) who underwent orthopedic surgery from January 2013 June 2019. mean follow-up period was 17.1 (1–60) months. Upon admission, all were assessed low...
The purpose of this study was to evaluate the implication gait speed, which is a prerequisite for diagnosis sarcopenia in older patients with lumbar spinal stenosis (LSS).This conducted total 235 LSS who underwent surgical treatment. state and pre-sarcopenia, including were evaluated before after operation.The proportion lower than at baseline levels skeletal muscle mass index (SMI) speed 27.2% 17.9%, respectively. Significant changes observed whereas SMI showed no significant differences...
A comprehensive analysis of clinical information in patients with chronic low back pain (CLBP) was performed to clarify the characteristics geriatric LBP from perspective body composition, spinal alignment, and blood findings related senescence. We enrolled 203 an average age 79.0 years (77 men 126 women), non-specific CLBP as a single-center prospective cohort study, were compared age- sex-matched controls without using propensity score-matching. laboratory analysis, radiographic...
Objectives The appropriate holistic management is mandatory for successful endoscopic ultrasound (EUS)‐guided treatment of pancreatic fluid collections (PFCs). However, comorbidity status has not been fully examined in relation to clinical outcomes this treatment. Methods Using a multi‐institutional cohort 406 patients receiving EUS‐guided PFCs 2010–2020, we the associations Charlson Comorbidity Index (CCI) with in‐hospital mortality and other outcomes. Multivariable logistic regression...
Retrospective clinical study.The objective of this study is to evaluate magnetic resonance imaging and pathologic features spinal schwannomas (SCHs) myxopapillary ependymomas (MPEs) with focus on differentiating 2 disease entities.Few studies have reported the differentiation SCHs MPEs.Fifty-three patients were retrospectively reviewed histologically confirmed (41 patients) or MPEs (12 cauda equina and/or conus medullaris. We evaluated neurological deterioration after surgery in association...
Study Design: This was a cross-sectional electrophysiological study. Objective: The main objective of this study to evaluate activation lumbar multifidus (LM) and erector spinae (ES) in elderly patients with chronic low back pain (CLBP) classified by LBP developmental mechanisms. Summary Background Data: Local global muscles that function independently for stabilization moment production, respectively, are crucial stability mobility the spine. There is little research conducted on functions...
Ligamentum flavum (LF) hypertrophy is the main etiological factor in development of lumbar spinal stenosis (LSS); however, its molecular pathology remains unclear. Histologically, LF characterized by a reduction elastic fibers and an increase collagen fibers. We previously performed miRNA transcriptomic analysis on excised from elderly patients with LSS identified insulin receptor signaling along TGFβ-mediated as pathways involved ligament hypertrophy. Therefore, this study aimed to...
The national prevalence of autoimmune and secondary PAP rose during the past decade. prognoses congenital were particularly poor, highlighting need for further research mechanisms underlying these diseases. https://bit.ly/3Z7uBkg.
Laboratory experiments have indicated that calcium channel blockers (CCBs) inhibit the entry and replication of influenza A virus in cells. However, no clinical studies assessed incidence among patients receiving CCBs. This study aimed to investigate association between CCB use with hypertension using administrative claims data Japan.
Perioperative skin injury is a major issue; therefore, several preventative measures have been developed. However, no previous studies visualized the effects of stromal edema caused by surgical invasion tissue, and details remain unknown. We used an ultrasonic diagnostic imaging device to clarify changes in tissue structure patients after open surgery.Twenty subjects who underwent hepatectomy were enrolled. selected lateral abdomen, upper arms, lower legs as measurement sites. performed...