A5044651846- Renal Transplantation Outcomes and Treatments
- Organ Donation and Transplantation
- Renal Diseases and Glomerulopathies
- Transplantation: Methods and Outcomes
- Neurological and metabolic disorders
- Cytomegalovirus and herpesvirus research
- Urticaria and Related Conditions
- Dialysis and Renal Disease Management
- Chronic Kidney Disease and Diabetes
- Dermatology and Skin Diseases
- Hepatitis C virus research
- Neurological Complications and Syndromes
- Psoriasis: Treatment and Pathogenesis
- COVID-19 Clinical Research Studies
- Sepsis Diagnosis and Treatment
- Acute Kidney Injury Research
- Moyamoya disease diagnosis and treatment
- Renal and Vascular Pathologies
- Frailty in Older Adults
- Blood Pressure and Hypertension Studies
Columbia University
2020-2024
NewYork–Presbyterian Hospital
2020-2021
New York Hospital Queens
2021
Columbia University Irving Medical Center
2020
Jacobi Medical Center
2016
Introduction A large proportion of patients with COVID-19 develop acute kidney injury (AKI). While the most severe these cases require renal replacement therapy (RRT), little is known about their clinical course. Methods We describe characteristics in ICU AKI requiring RRT at an academic medical center New York City and followed for outcomes death recovery using time-to-event analyses. Results Our cohort 115 represented 23% all admissions our center, a peak prevalence 29%. Patients were...
Background and objectives Unfavorable histology on procurement biopsies is the most common reason for deceased donor kidney discard. We sought to assess reproducibility of biopsy findings. Design, setting, participants, & measurements compiled a continuous cohort kidneys transplanted at our institution from 1/1/2006 12/31/2016 that had least one performed, excluded cases with missing reports those used in multiorgan transplants. Suboptimal was defined as presence advanced sclerosis...
The factors that influence deceased donor kidney procurement biopsy reliability are not well established. We examined the impact of technique and pathologist training on accuracy.We retrospectively identified all kidney-only transplants at our center from 2006 to 2016 with both reperfusion biopsies performed information available (n = 392). Biopsies were scored using a previously validated system, classifying "suboptimal" histology as presence least 1 following: glomerulosclerosis ≥11%,...
While outcomes from HCV-positive and HCV-negative donor kidneys are comparable in the short term, questions remain about clinical consequences of preexisting HCV-related kidney injury, which may go undetected at time organ procurement.1-5 We previously reported a case successful transplantation an with mesangial proliferative glomerulonephritis (GN) into recipient reversal HCV-associated histologic changes after antiviral treatment.
To evaluate the role of circulating dd-cfDNA in allograft surveillance immunologically high-risk patients, a retrospective cross-sectional study 261 kidney transplant recipients who underwent outpatient biopsy at our center between September 2020 and August 2021 was performed. Of 236 results included, 37 samples were obtained time sensitized 199 clinically indicated biopsy. The median serum creatinine 1.3 mg/dl 2.1 for biopsies biopsies, respectively (P < .001). Rejection diagnosed 27% 29%...
Introduction . Posterior reversible encephalopathy syndrome (PRES) is a constellation of clinical and radiologic findings. Fluctuations in blood pressure, seizures, brain MRI findings mainly posterior cerebral white matter are the main manifestations. PRES has been associated with multiple conditions such as autoimmune disorders, pregnancy, organ transplant, thrombotic microangiopathy (TMA). Case Presentation A 22-year-old woman history Systemic Lupus Erythematous complicated chronic kidney...
The assessment of chronic changes in deceased donor kidney procurement biopsies contributes to organ underutilization, but these have poor reproducibility and inconsistent associations with post-transplant outcomes despite the frequency which they are used determine whether donated kidneys transplantable.1Carpenter D. Husain S.A. Brennan C. et al.Procurement evaluation kidneys.Clin J Am Soc Nephrol. 2018; 13: 1876-1885https://doi.org/10.2215/CJN.04150418Crossref PubMed Scopus (41) Google...