Julien Ternacle
A5045161831- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Cardiac Structural Anomalies and Repair
- Aortic Disease and Treatment Approaches
- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Antimicrobial Resistance in Staphylococcus
- Mechanical Circulatory Support Devices
- Cardiac, Anesthesia and Surgical Outcomes
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Acute Myocardial Infarction Research
- Orthopedic Infections and Treatments
- Cardiomyopathy and Myosin Studies
- Pulmonary Hypertension Research and Treatments
- Ultrasound in Clinical Applications
- Cardiac Arrest and Resuscitation
- Heart Failure Treatment and Management
- Cardiovascular Disease and Adiposity
- Adipose Tissue and Metabolism
- Parathyroid Disorders and Treatments
- Heart rate and cardiovascular health
- Infectious Aortic and Vascular Conditions
Centre Hospitalier Universitaire de Bordeaux
2021-2025
Hôpital Cardiologique du Haut-Lévêque
2020-2025
Université de Bordeaux
2021-2025
Assistance Publique – Hôpitaux de Paris
2013-2024
Lille’s Cardiology Hospital
2022-2024
Université Laval
2019-2024
Institut Mondor de Recherche Biomédicale
2015-2024
Hôpital Civil, Strasbourg
2024
Université de Strasbourg
2024
Montreal Heart Institute
2020-2024
A previous analysis in this trial showed that among patients with severe, symptomatic aortic stenosis who were at low surgical risk, the rate of composite end point death, stroke, or rehospitalization 1 year was significantly lower transcatheter aortic-valve replacement (TAVR) than replacement. Longer-term outcomes are unknown.
Short-term clinical outcomes after transcatheter aortic valve replacement (TAVR) are similar in individuals with small or large annuli. The longer term impact of prosthesis-patient mismatch (PPM) and mean gradient (MG) post-TAVR these patients remains controversial. aim this study was to investigate 5-year vs Patients from the PARTNER (Placement Aortic Transcatheter Valves) 2 SAPIEN 3 intermediate-risk registry low-risk randomized controlled trial were grouped according (≤430 mm2) (>430...
Abstract Aims Valve durability becomes a major issue as transcatheter aortic valve implantation (TAVI) is expanding to populations with longer life expectancy. We sought i) determine the incidence of structural deterioration (SVD), ii) compare SVD between balloon-expandable (BE) and self-expandable (SE) valves, iii) analyze impact SVD. Methods Results 2040 patients who underwent TAVI (2007-2020) from 9 centers were included. After inverse probability treatment weighting (IPTW), 1848 selected...
Background: Aging induces cardiac structural and functional changes linked to the increased deposition of extracellular matrix proteins, including OPN (osteopontin), conducing progressive interstitial fibrosis. Although is involved in various pathological conditions, its role myocardial aging remains unknown. Methods: deficient mice (OPN-/-) with their wild-type (WT) littermates were evaluated at 2 14 months age terms structure, function, histology key molecular markers. expression was...
Background: This study aimed to compare echocardiographic findings in low-risk patients with severe aortic stenosis after surgical valve replacement (SAVR) or transcatheter (TAVR). Methods: The PARTNER 3 trial (Placement of Aortic Transcatheter Valves) randomized 1000 and low risk undergo either transfemoral TAVR the balloon-expandable SAPIEN SAVR. Transthoracic echocardiograms obtained at baseline 30 days 1 year procedure were analyzed by a consortium 2 echocardiography core laboratories....
Background: Right ventricular (RV) dysfunction is a strong predictor of poor outcomes in heart failure. Its prognostic meaning cardiac amyloidosis (CA) under-investigated.Methods: Hundred and twenty nine patients with suspected CA an interventricular septum thickness (IVST) ≥ 12 mm underwent echocardiography measurement left (LV) RV longitudinal strain (LS), late gadolinium-enhancement (LGE) MRI, standard evaluation.Results: Among 82 confirmed CA, types were immunoglobulin light chain (AL, n...
This study aimed to compare incidence and impact of measured prosthesis-patient mismatch (PPMM) versus predicted PPM (PPMP) after surgical aortic valve replacement (SAVR) transcatheter (TAVR). TAVR studies have used effective orifice area indexed (EOAi) body surface (BSA) define PPM, but most SAVR series EOAi. difference may contribute discrepancies in outcomes between series. The analyzed patients from the PARTNER (Placement Aortic Transcatheter Valves) 2A trial 2 SAPIEN 3 Intermediate Risk...
Even though vegetation size in infective endocarditis (IE) has been associated with embolic events (EEs) and mortality risk, it is unclear whether these potential outcomes different left-sided IE (LSIE). This study aimed to seek assessing the cut-off as predictor of EE or 30-day for LSIE determine risk predictors outcomes.The European Society Cardiology EURObservational Research Programme Infective Endocarditis a prospective, multicentre registry including patients definite possible...
Abstract Background and Aims This trial sought to assess the safety efficacy of ShortCut, first dedicated leaflet modification device, prior transcatheter aortic valve implantation (TAVI) in patients at risk for coronary artery obstruction. Methods pivotal prospective study enrolled with failed bioprosthetic valves scheduled undergo TAVI were The primary endpoint was procedure-related mortality or stroke discharge 7 days, per-patient splitting success. Independent angiographic,...
Global longitudinal strain (GLS) seems accurate for detecting subclinical myocardial dysfunction, and may therefore be used to improve risk stratification cardiac surgery.Longitudinal (by two-dimensional speckle tracking) was computed in 425 patients [mean age 67 ± 13 years, 69% male, left ventricular ejection fraction (LVEF) 51 13%] referred surgery [isolated coronary artery bypass graft (CABG) (n = 155), aortic valve 174), mitral 96)]. GLS (global-ε) assessed predicting early postoperative...
Abstract Aims The European Society of Cardiology (ESC) EURObservational Research Programme (EORP) Endocarditis (EURO-ENDO) registry aims to study the care and outcomes patients diagnosed with infective endocarditis (IE) compare findings recommendations from 2015 ESC Clinical Practice Guidelines for management IE data 2001 Euro Heart Survey. Methods results Patients (n = 3116) aged over 18 years a diagnosis based on diagnostic criteria were prospectively identified between 1 January 2016 31...
Abstract Aims The objective was to compare the incidence and impact on outcomes of measured (PPMM) vs. predicted (PPMP) prosthesis–patient mismatch following transcatheter aortic valve replacement (TAVR). Methods results All consecutives patients who underwent TAVR between 2007 2018 were included. Effective orifice area (EOA) by Doppler-echocardiography using continuity equation according normal reference for each model size valve. PPM defined EOA indexed (EOAi) body surface as moderate if...
Background Concerns about discordance between echocardiographic and invasive mean gradients after transcatheter aortic valve replacement (TAVR) with balloon-expandable valves (BEVs) versus self-expanding (SEVs) exist. Methods Results In a multicenter study, direct-invasive echocardiography-derived transvalvular obtained before TAVR were compared as well post-TAVR discharge in BEVs SEVs 808 patients. Pre-TAVR, there was good correlation (R=0.614; P<0.0001) weak (R=0.138; post-TAVR. Compared...