A5090593248- Axon Guidance and Neuronal Signaling
- Knee injuries and reconstruction techniques
- Wnt/β-catenin signaling in development and cancer
- Medical Malpractice and Liability Issues
- Orthopedic Surgery and Rehabilitation
- Hippo pathway signaling and YAP/TAZ
- Cancer-related gene regulation
- Traumatic Ocular and Foreign Body Injuries
- Bone and Joint Diseases
- Lymphoma Diagnosis and Treatment
- Osteoarthritis Treatment and Mechanisms
- dental development and anomalies
- Developmental Biology and Gene Regulation
- Musculoskeletal synovial abnormalities and treatments
- Cancer Diagnosis and Treatment
Loyola University Chicago
2025
Loyola University Medical Center
2025
Midwestern University
2020-2022
Oral squamous cell carcinoma (OSCC) is a common epithelial malignancy of the oral cavity. Nodal and Cripto-1 (CR-1) are important developmental morphogens expressed in several adult cancers associated with disease progression. Whether CR-1 simultaneously same tumor how this affects cancer biology unclear. We investigate expression potential role both human OSCC. Immunohistochemistry results show that OSCC sample intensity staining correlated advanced-stage disease. However, was not observed...
Netrin-1 is a neural guidance factor that regulates migration and positioning of crest-derived cells during embryonic development. Depending on the type receptor expression, are either attracted or repulsed by Netrin-1. Postnatal expression detected in brain, colon, liver, kidney, which common sites cancer metastasis, including melanoma. Thus, understanding dynamics between its receptors could explain attraction melanoma towards these Netrin-1-expressing tissues. Here, we investigate whether...
Trans-scaphoid lunate dislocation with volar displacement into the wrist/distal forearm is a devastating injury that most commonly occurs under situations of forceful impact to an extended wrist. Due ligamentous disruption as well fragile blood supply, these Mayfield type 4 injuries are associated significant morbidity and long-term sequelae. Current treatment approaches dislocations depend on severity chronicity in addition patient factors, operative management potentially including ORIF or...