A5061588773- Diet and metabolism studies
- Bariatric Surgery and Outcomes
- Gut microbiota and health
- Inflammatory Bowel Disease
- Gastric Cancer Management and Outcomes
- Microscopic Colitis
- Nutrition and Health in Aging
- Nutritional Studies and Diet
- Enhanced Recovery After Surgery
- Health and Lifestyle Studies
- Genetic and phenotypic traits in livestock
- Clostridium difficile and Clostridium perfringens research
- Diabetes Treatment and Management
- Obesity, Physical Activity, Diet
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Hormonal Regulation and Hypertension
- Effects of Environmental Stressors on Livestock
- Academic Research in Diverse Fields
- Milk Quality and Mastitis in Dairy Cows
- Ruminant Nutrition and Digestive Physiology
- Esophageal and GI Pathology
- Fatty Acid Research and Health
- Systemic Lupus Erythematosus Research
- Environmental and biological studies
- Helicobacter pylori-related gastroenterology studies
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2020-2024
Universidade de São Paulo
2016-2023
Centro Universitário das Faculdades Metropolitanas Unidas
2021
Centro Hospitalar de Vila Nova de Gaia
2021
Faculdade Evangélica do Paraná
2020
Centro Universitário São Camilo
2016
Gut microbiota composition is influenced by environmental factors and has been shown to impact body metabolism. Objective: To assess the gut profile before after Roux-en-Y gastric bypass (RYGB) correlation with food intake postoperative type 2 diabetes remission (T2Dr). Design: from obese diabetic women was evaluated (n = 25) 3 20) 12 months 14) RYGB, using MiSeq Illumina-based V4 bacterial 16S rRNA gene profiling. Data on (7-day record) T2Dr (American Diabetes Association (ADA) criteria)...
Inflammatory bowel diseases (IBD) are chronic conditions arising from an intricate interplay of genetics and environmental factors, associated with gut dysbiosis, inflammation, permeability. In this study, we investigated whether the inflammatory potential diet is microbiota profile, permeability in forty patients IBD clinical remission. The dietary index (DII) score was used to assess diet. fecal profile analyzed using 16SrRNA (V3-V4) gene sequencing, while zonulin calprotectin levels were...
SummaryBody composition has great importance in the value of energy expenditure. Reduced expenditure plays an important role development obesity by decreasing resting expenditure, activity, diet-induced thermogenesis, or a combination all these components. It thus contributes to positive balance and subsequent weight gain. Obesity, therefore, can be considered, among other aspects, consequence imbalance; that is, intake greater than spent certain period. In order have stability body it would...
The etiology of systemic lupus erythematosus (SLE) remains unclear, with both genetic and environmental factors potentially contributing. This study aimed to explore the relationship among gut microbiota (GM), intestinal permeability, food intake inflammatory markers in inactive SLE patients. A total 22 women 20 healthy volunteers were enrolled, dietary was assessed through 24-h recalls. Plasma zonulin used evaluate while GM determined by 16S rRNA sequencing. Regression models analyze...
Gut microbiota has been implicated in various clinical conditions, yet the substantial heterogeneity gut research results necessitates a more sophisticated approach than merely identifying statistically different microbial taxa between healthy and unhealthy individuals. Our study seeks to not only select but also explore their synergy with phenotypic host variables develop novel predictive models for specific conditions. Design: We assessed 50 152 individuals (PV) (GM) composition by 16S...
Roux-en-Y Gastric bypass (RYGB) promotes improvement in type 2 diabetes (T2D) shortly after surgery, with metabolic mechanisms yet to be elucidated. This study aimed investigate the relationship between food intake, tryptophan metabolism, and gut microbiota on glycemic control of obese T2D women RYGB surgery. Twenty who underwent were evaluated before three months Food intake data obtained by a seven-day record frequency questionnaire. Tryptophan metabolites determined untargeted metabolomic...
Objective To describe the protocol of SURgically induced Metabolic effects on Human GastroIntestinal Tract (SURMetaGIT) study, a clinical pan-omics study exploring gastrointestinal tract as central organ driving remission type 2 diabetes mellitus (T2DM) after Roux-en-Y gastric bypass (RYGB). The main points considered in study's design and challenges faced its application are detailed. Methods This observational, longitudinal, prospective involved collection biopsy specimens, faeces, urine,...
OBJECTIVES: Vitamin B12 (B12) deficiency after Roux-en-Y gastric bypass (RYGB) is highly prevalent and may contribute to postoperative complications. Decreased production of intrinsic factor owing fundus removal thought have a major role, but other components metabolism also be affected. We evaluated changes in the expression levels multiple pathway-encoding genes gastrointestinal (GI) tissues evaluate potential roles contributing post-RYGB deficiency. METHODS: During double-balloon...
Abstract We evaluated whether the excluded stomach (ES) after Roux-en-Y gastric bypass (RYGB) can represent a premalignant environment. Twenty obese women were prospectively submitted to double-balloon enteroscopy (DBE) with juice and biopsy collection, before 3 months RYGB. then morphological molecular changes by combining endoscopic histopathological analyses an integrated untargeted metabolomics transcriptomics multiplatform. Preoperatively, 16 already presented alterations increased pH...