- Corneal Surgery and Treatments
- Corneal surgery and disorders
- Ocular Surface and Contact Lens
- Glaucoma and retinal disorders
- Ocular Infections and Treatments
- Ocular Diseases and Behçet’s Syndrome
- Intraocular Surgery and Lenses
- Mesenchymal stem cell research
- Herpesvirus Infections and Treatments
- Cerebrovascular and Carotid Artery Diseases
- Ocular Oncology and Treatments
- Contact Dermatitis and Allergies
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Salivary Gland Disorders and Functions
- Dermatology and Skin Diseases
- Ophthalmology and Eye Disorders
- Biomedical Research and Pathophysiology
- Immunodeficiency and Autoimmune Disorders
- Cytomegalovirus and herpesvirus research
- Ocular Disorders and Treatments
- Retinopathy of Prematurity Studies
- Retinal Diseases and Treatments
- Aluminum toxicity and tolerance in plants and animals
- Sympathectomy and Hyperhidrosis Treatments
- Poxvirus research and outbreaks
Hospital Universitario La Paz
2013-2024
Clínica Rementería
2013-2023
Hospital La Paz Institute for Health Research
2013-2018
Instituto Cajal
2012
Hospital Universitario San Rafael
2005
Hospital Juan Ramón Jiménez
1998-2002
Purpose To determine the safety and feasibility of human autologous adipose tissue-derived adult mesenchymal stem cells (ASCs) for ocular surface regeneration in patients with bilateral limbal stem-cell deficiency (LSCD).
A case of ocular pythiosis successfully treated with surgery and intraocular oral minocycline is reported.A 30-year-old man who wore corrective contact lenses traveled to Brazil Colombia where he swam in salt fresh waters while wearing lenses. He sought treatment at an emergency department after 2 weeks suffering a painful corneal ulcer, redness, loss vision his right eye that had been other centers ophthalmic moxifloxacin for 10 days fortified topical antibiotics (amikacin vancomycin) days....
To evaluate the sensitivity and specificity of a PCR-strip system based on reverse dot blot for detection MUC5AC mRNA in corneal epithelium samples from patients with limbal stem cell deficiency (LSCD), to determine correlation clinical diagnosis.We obtained 87 impression cytology (IC) 55 subjects (37 clinically diagnosed LSCD 18 control subjects). Total RNA was extracted each IC sample retrotranscribed cDNA. transcript amplified by customized RT-PCR assay detected PCR strips hybridization...
Purpose: The purpose of this study was to report a case peripheral ulcerative keratitis in patient diagnosed with corneal polymerase chain reaction (PCR) and positive mpox culture. Methods: This is report. Results: An immunocompetent 54-year-old man conjunctivitis his left eye 15 days after being mucocutaneous monkeypox. He received treatment dexamethasone 0.1% tobramycin 0.3% drops for 2 weeks. Two weeks discontinuing treatment, he developed paracentral epithelial defect. Mpox by culture...
This article examines the clinical presentation of ocular metastasis from an infiltrating lobular breast carcinoma. We examined a conjunctival biopsy 69-year-old woman who developed unilateral inflammation together with neurotrophic corneal ulcer and proptosis. Infiltrating carcinoma (ILBC) was diagnosed using routine histology immunohistochemistry. She had past history hormone receptor-positive ILBC 11 years ago cutaneous diffuse osteoblastic metastases, she kept under treatment lezotrol....
To investigate the ocular surface changes occurring in eyes with recurrent pterygium post-operatively treated 5-fluorouracil intralesional injections.Retrospective observational study of cases weekly injections 0.1 mL (5 mg) (10 injections). Impression cytology samples taken from lesion, healthy conjunctivae (inferior, superior, and contralateral to injury), cornea before after treatment were analyzed. Clinical characteristics (including Schirmer's test break-up time) evaluated during...
To report a case of atypical herpes keratitis and bilateral conjunctivitis associated with human herpesvirus 6 (HHV-6).An immunocompetent 34-year-old man was referred for herpetic epithelial in his left eye, which non-responsive to topical acyclovir. Biomicroscopy revealed central dendritic ulcer white stromal infiltrate beneath the ulcer.The corneal scraping multiplex polymerase chain reaction (CLART ENTHERPEX, Genomica, Spain) positive HHV-6 negative simplex virus, varicella zoster...
We studied three patients who developed left unilateral punctate keratitis after suffering left-sided Wallenberg Syndrome. A complex evolution occurred in two of them. In all cases, neurophysiological studies showed damage the trigeminal sensory component at bulbar level. Corneal involvement secondary to syndrome is a rare cause superficial keratitis. The loss corneal sensitivity caused by neuropathy leads epithelial erosions that are frequently unobserved patient, resulting high risk...
The presence of apolipoprotein D (apoD) synthesis in brain suggests that this protein could play a major role mediating neuronal degeneration and regeneration the central nervous system (CNS). For instance, apoD is overexpressed neural tissues Niemann-Pick's type C disease, after acute CNS injury cerebral ischemia, Alzheimer's disease by number different tumors such as breast, prostate, ovarian endometrial carcinomas. Recent data have raised possibility expression be marker cellular...
Sarcoidosis is a relatively uncommon multi‐systemic chronic granulomatous disease, which might affect any organ of the body, with lungs, lymph nodes, skin and eyes most frequently involved.1–4 ...
To describe a series of 5 patients with herpes simplex virus keratitis (HSK) and rheumatoid arthritis (RA) under immunosuppressive treatment.Retrospective study. Detailed data were obtained regarding symptoms signs at the initial evaluation, treatment, microbiological diagnostic tests, evolution, outcomes.Five HSK RA identified. Bilateral involvement occurred in 2 (40%). Epithelial was diagnosed eyes. Three eyes showed severe melting eye perforation. Gram-positive bacterial co-infections...