A5103277083- Animal Nutrition and Physiology
- Genetic and phenotypic traits in livestock
- Adipose Tissue and Metabolism
- interferon and immune responses
- Genetic Mapping and Diversity in Plants and Animals
- Aquaculture disease management and microbiota
- Adipokines, Inflammation, and Metabolic Diseases
- Influenza Virus Research Studies
- Immune Response and Inflammation
- Chemokine receptors and signaling
- Animal Genetics and Reproduction
- Salmonella and Campylobacter epidemiology
- MicroRNA in disease regulation
- Peroxisome Proliferator-Activated Receptors
- Ubiquitin and proteasome pathways
- Catalytic Processes in Materials Science
- RNA modifications and cancer
- Microgrid Control and Optimization
- HVDC Systems and Fault Protection
- Gut microbiota and health
- Catalysts for Methane Reforming
- Animal Virus Infections Studies
- Livestock and Poultry Management
- Advanced Photocatalysis Techniques
- Cancer-related molecular mechanisms research
Fujian Institute of Research on the Structure of Matter
2024-2025
Chinese Academy of Sciences
2016-2025
Fujian Normal University
2024-2025
Yancheng Third People's Hospital
2016-2024
Jiangsu Vocational College of Medicine
2024
Chinese Academy of Agricultural Sciences
2015-2024
Ministry of Agriculture and Rural Affairs
2022-2024
Institute of Animal Sciences
2015-2024
Third Affiliated Hospital of Southern Medical University
2024
Huazhong University of Science and Technology
2024
Cytosine DNA methylation is an important epigenetic modification termed as the fifth base that functions in diverse processes. Till now, genome-wide maps of many organisms has been reported, such human, Arabidopsis, rice and silkworm, but pattern bird remains rarely studied. Here we show map bird, using chicken a model organism immunocapturing approach followed by high-throughput sequencing. In both red jungle fowl avian broiler, was described separately for liver muscle tissue. Generally,...
Investigating the genetic markers and genomic signatures related to chicken meat production by combing multi-omics methods could provide new insights into modern breeding technology systems. Chicken is one of most efficient environmentally friendly livestock, especially fast-growing white-feathered (broiler), which well known for high yield, but underlying basis poorly understood. We generated whole-genome resequencing three purebred broilers (n = 748) six local breeds/lines 114), sequencing...
China has the richest local chicken breeding resources in world and is world's second largest producer of meat-type chickens. Development a moderate-density SNP array for genetic analysis chickens taking utility those urgently needed conventional farms, industry, research areas. Eight representative breeds or commercial broiler lines with 3 pools 48 individuals within each breed/line were sequenced supplied major SNPs resource. There 7.09 million - 9.41 detected breed/line. After filtering...
The synthesis of polyureas from CO<sub>2</sub> and diamines with a functional ionic liquid as the catalyst.
Abstract Background Feed accounts for about 70% of the total cost poultry meat production. Residual feed intake (RFI) has become preferred measure efficiency because it is phenotypically independent growth rate and body weight. In this study, our aim was to estimate genetic parameters identify quantitative trait loci (QTL) in 3314 purebred broilers using a genome-wide association study. Broilers were genotyped custom 55 K single nucleotide polymorphism (SNP) array. Results Estimates genomic...
Skeletal muscle development is closely linked to meat production and its quality. This study the first quantify proteomes metabolomes of breast in two distinct chicken breeds at embryonic day 12 (ED 12), ED 17, post-hatch D 1 14 using mass spectrometry-based approaches.Results found that intramuscular fat (IMF) accumulation increased from 17 was exactly opposite when most obvious growth occurred - 14). For slow-growing Beijing-You chickens, Ingenuity Pathway Analysis 77-99 differential...
Muscle development and growth influences the efficiency of poultry meat production, is closely related to deposition intramuscular fat (IMF), which crucial in quality. To clarify molecular mechanisms underlying muscle IMF chickens, protein expression profiles were examined breast Beijing-You chickens at ages 1, 56, 98 140 days, using isobaric tags for relative absolute quantification (iTRAQ). Two hundred four 494 proteins expressed differentially. The profile day 1 differed greatly from...
In broiler production, there is a continuous effort to breed feed efficient chickens. Residual intake (RFI) an accurate indicator that has been accepted as alternative measure of the conventional conversion ratio. This study conducted duodenal transcriptome survey explore molecular basis RFI. Results showed are 599 genes were differentially expressed (DE) in duodenum between high RFI and low (LRFI) broilers. Functional analysis can be explained by differences regulation immune system...
Abstract We investigated the effects of inulin on intestinal barrier function and mucosal immunity in Salmonella enterica serovar Enteritidis (SE)–infected specific pathogen-free (SPF) chickens. SPF chickens (n = 240, 1-d-old) were divided into 4 groups (6 replicates per group, 10 replicate): a control group (CON) fed basal diet without supplementation 3 SE-infected supplemented with 0% (SE group), 0.5% (0.5% InSE 1% (1% respectively. At 28 d age, orally infected SE CON administrated...
As a canonical adaptor for the Toll-like receptor (TLR) family, myeloid differentiation primary response protein 88 (MyD88) has crucial roles in host defense against infection by microbial pathogens, and its dysregulation might induce autoimmune diseases. Here, we demonstrate that chicken Cullin 3-based ubiquitin ligase Speckle-type BTB–POZ (chSPOP) recognizes intermediate domain of MyD88 (chMyD88) degrades it through proteasome pathway. Knockdown or genetic ablation chSPOP leads to aberrant...
The switch of CO2 hydrogenation selectivity from CH4 to CO over TiO2 supported Rh catalysts is accomplished via selective encapsulation nanoparticles while exposing single atoms by high-temperature reduction (HTR) according their different strong metal-support interaction (SMSI) occurrence conditions, which can be reversed subsequent oxidation treatment.
The gastrointestinal microbiota plays a vital role in ensuring the maintenance of host health through interactions with immune system. Heterophil/Lymphocyte (H/L) ratio reflects poultry's robustness and system status. Chickens low H/L are superior to chickens high survival, response, resistance Salmonella infection, but underlying mechanisms remain unclear. This study aimed identify microorganisms associated Enteritidis infection based on ratio. 16S rRNA metagenomic analysis were conducted...
Due to high selection advances and shortened generation interval, genomic (GS) is now an effective animal breeding scheme. In broilers, many studies have compared the accuracy of different GS prediction methods, but few reports demonstrated phenotypic or genetic changes using GS. this study, paternal chicken line B underwent continuous for 3 generations. The 55 k SNP chip was used estimate parameters detect response regions by selective sweep analysis. heritability body weight (BW), meat...
Growing evidence has demonstrated that the nucleotide‑binding oligomerization domain‑like receptor family pyrin domain containing 3 (NLRP‑3) inflammasome‑mediated inflammatory pathways have been involved in secondary injury of traumatic brain (TBI). In present study, authors investigated effects hyperbaric oxygen (HBO) therapy on NLRP‑3 inflammasome pathway following TBI. Following evaluation motor deficits and edema, therapeutic HBO interleukin (IL)‑1β IL‑18 expression were assessed, as...
Skeletal muscle satellite cells (MSC) are crucial for postnatal growth and regeneration of skeletal muscle. An interaction exists between MSC intramuscular preadipocytes (IMPA). This study is the first to investigate effects IMPA on in chickens unveil molecular mechanisms by transcriptome analysis.Primary were isolated from pectoralis major 7-day-old chickens. After both cell types reached confluence, cultured alone or co-cultured with 2 4 d. treated d subjected RNA-seq. A total 1653 known...
The title reaction involves metal free TEAB-catalyzed S–S bond cleavage, C–S formation and C–C formation; it uses readily available disulfides alkynes as substrates, environmentally friendly TEAB catalyst to synthesize useful benzothiophene derivatives.
To develop an independent prognostic signature for patients with hepatocellular carcinoma (HCC).HCC gene expression profile the cancer genome atlas-liver and GSE14520 were used as discovery test set, respectively. Differentially expressed genes (DEGs) identified between HCC tissues adjacent normal liver tissues. Univariate Cox proportional hazards regression analysis was performed to identify DEGs correlated survival of patients. A 4-gene-based constructed based on a least absolute shrinkage...
Fatty liver is a widespread disease in chickens that causes decrease egg production and even death. The characteristics of the inherited phenotype acquired fatty molecular mechanisms underlying it, however, are largely unknown. In current study, was induced 3 breeds by high-fat (HF) diet methionine choline-deficient (MCD) diet. results showed dwarf Jingxing-Huang (JXH) chicken more susceptible to compared with layer White Leghorns (WL) local Beijing-You (BJY) breeds. addition, it found...
The current study investigated the effects of inulin on gut microbiota, microbiome functions, and short-chain fatty acids (SCFAs) levels in specific pathogen-free (SPF) chickens infected with Salmonella enteritidis (SE). SPF Arbor Acres ( n = 240, 1-day-old) were divided into four groups: a control group (CON) fed basal diet without supplementation or SE infection, three groups supplemented 0, 0.5, 1% (SE, 0.5%InSE, 1%InSE, respectively) up to 28-days-old, followed by challenge at 28 days...