A5039148082- Pain Management and Placebo Effect
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Musculoskeletal pain and rehabilitation
- Psychosomatic Disorders and Their Treatments
- Heart Rate Variability and Autonomic Control
- Pain Mechanisms and Treatments
- Neural and Behavioral Psychology Studies
- EEG and Brain-Computer Interfaces
- Action Observation and Synchronization
- Complementary and Alternative Medicine Studies
- Functional Brain Connectivity Studies
- Advanced Neuroimaging Techniques and Applications
- Acupuncture Treatment Research Studies
- Color perception and design
- Mind wandering and attention
- Olfactory and Sensory Function Studies
- Advanced MRI Techniques and Applications
- Genetic Neurodegenerative Diseases
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Neural dynamics and brain function
- Attention Deficit Hyperactivity Disorder
- Vagus Nerve Stimulation Research
- Intensive Care Unit Cognitive Disorders
- Aesthetic Perception and Analysis
Spaulding Rehabilitation Hospital
2022-2023
Harvard University
2020-2023
Massachusetts General Hospital
2020-2023
Athinoula A. Martinos Center for Biomedical Imaging
2020-2023
National Center for Complementary and Integrative Health
2023
Institute of Art
2023
Boston University
2022
Stony Brook University
2021
Universität Hamburg
2018
ETH Zurich
2018
The anticipation of favourable or unfavourable events is a key component in our daily life. However, the temporal dynamics processes relation to brain activation are still not fully understood. A modified version monetary incentive delay task was administered during separate functional magnetic resonance imaging (fMRI) and electroencephalogram (EEG) sessions same 25 participants assess anticipatory with multi-modal neuroimaging set-up. During fMRI, gain loss were both associated heightened...
Abstract Objectives: Anticipatory processes prepare the organism for upcoming experiences. The aim of this study was to investigate neural responses related anticipation and processing painful stimuli occurring with different levels uncertainty. Experimental design: Twenty‐five participants (13 females) took part in an electroencephalography functional magnetic resonance imaging (fMRI) experiment at separate times. A visual cue announced occurrence electrical or nonpainful stimulus,...
In placebo hypoalgesia research, the strength of treatment expectations and experiences are key components. However, reliability or precision had been mostly ignored although being a likely source for interindividual differences. present study, we adopted Bayesian framework, naturally combining expectation magnitudes precisions. This postulates that (prior) integrated with incoming nociceptive information (likelihood) both weighted by their relative to form pain percept effect. Sixty-two...
Social interactions such as the patient-clinician encounter can influence pain, but underlying dynamic interbrain processes are unclear. Here, we investigated brain supporting social modulation of pain by assessing simultaneous activity (fMRI hyperscanning) from chronic patients and clinicians during video-based live interaction. Patients received painful nonpainful pressure stimuli either with a supportive clinician present (Dyadic) or in isolation (Solo). In half dyads, performed clinical...
Pain catastrophizing is prominent in chronic pain conditions such as fibromyalgia and has been proposed to contribute the development of widespreadness. However, brain mechanisms responsible for this association are unknown. We hypothesized that increased resting salience network (SLN) connectivity nodes default mode (DMN), representing previously reported pain-linked cross-network enmeshment, would be associated with widespreadness across body sites. applied functional magnetic resonance...
Objective Fibromyalgia (FM) is characterized by pervasive pain‐related symptomatology and high levels of negative affect. Mind–body treatments such as cognitive behavioral therapy (CBT) appear to foster improvement in FM via reductions catastrophizing, a set negative, pain‐amplifying emotional processes. However, the neural underpinnings CBT's catastrophizing‐reducing effects remain uncertain. This randomized controlled mechanistic trial was designed assess on pain catastrophizing its...
Abnormal central pain processing is a leading cause of in fibromyalgia (FM) and perceptually characterized with the psychophysical measure temporal summation (TSP). TSP perception increasingly greater response to repetitive or tonic noxious stimuli. Previous neuroimaging studies have used static (i.e., summary) measures examine functional magnetic resonance imaging (fMRI) correlates FM. However, brain activity rapidly dynamically reorganizes over time, and, similarly, temporally evolving...
Does a bottle elicit gender-specific emotion response that varies as function of its shape? The answer to this question is basic interest well specific the industry. We introduced startle reflex modulation objectively measure emotion-related aspects different bottles. This approach was chosen complete behavioural data with objective physiological data. Three bottles differing only in shape were used test stimuli. It known magnitude an eye blink acoustic stimulation reflects current elicited...
The patient-clinician relationship is known to significantly affect the pain experience, as empathy, mutual trust and therapeutic alliance can modulate perception influence clinical therapy outcomes. aim of present study was use an EEG hyperscanning setup identify brain behavioral mechanisms supporting while this dyad engaged in a interaction. Our previous applied fMRI investigate whether concordance linked with analgesia experienced by patient undergoing treatment clinician. In current...
Fibromyalgia is a centralized multidimensional chronic pain syndrome, but its pathophysiology not fully understood.We applied 3D magnetic resonance spectroscopic imaging (MRSI), covering multiple cortical and subcortical brain regions, to investigate the association between neuro-metabolite (e.g. combined glutamate glutamine, Glx; myo-inositol, mIno; (total) N-acetylaspartate N-acetylaspartylglutamate, tNAA) levels clinical/behavioural variables catastrophizing, clinical severity evoked...
Abstract Objective Chronic pain can have detrimental effects on quality of life and a profound impact one’s identity. The Pictorial Representation Illness- Self-Measure (PRISM), is visual tool designed to measure the self-illness separation (SIS) that represents degree schema-enmeshment (i.e., which self-schema illness-schema come overlap). Our aim was investigate relationship between pain-related outcomes in patients with fibromyalgia. Methods In this cross-sectional study, 114 fibromyalgia...
Vagus nerve stimulation (VNS) has many clinical applications under development. In particular, there is a large interest in transcutaneous auricular VNS (taVNS) because it non-invasive and provides easy access to neuromodulation. The present study proposes novel approach for electroencephalography (EEG)-gated taVNS, with the ultimate goal of enhancing therapeutic outcomes, including treatment delirium. Delirium arises from an altered state consciousness most common neuropsychiatric disorder...