A5101811650- Pain Management and Placebo Effect
- Complementary and Alternative Medicine Studies
- Gastrointestinal motility and disorders
- Empathy and Medical Education
- Psychosomatic Disorders and Their Treatments
- Acupuncture Treatment Research Studies
- Action Observation and Synchronization
- Mental Health and Psychiatry
- Clostridium difficile and Clostridium perfringens research
- Congenital gastrointestinal and neural anomalies
- Psychotherapy Techniques and Applications
- Gastroesophageal reflux and treatments
- Gut microbiota and health
- Diet and metabolism studies
- Substance Abuse Treatment and Outcomes
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Intergenerational Family Dynamics and Caregiving
- Musculoskeletal pain and rehabilitation
- Ocular Surface and Contact Lens
- Geriatric Care and Nursing Homes
- Pathogenesis and Treatment of Hiccups
- Facial Rejuvenation and Surgery Techniques
- Psychopathy, Forensic Psychiatry, Sexual Offending
- Chemokine receptors and signaling
- Health Policy Implementation Science
Endicott College
2009-2023
Harvard University
2010-2023
Beth Israel Deaconess Medical Center
2012-2023
Spaulding Rehabilitation Hospital
2022-2023
Bassett Medical Center
2022
University of Rome Tor Vergata
2021
Gold Coast Hospital
2019
Augusta University
2014
Massachusetts General Hospital
2006-2012
Albany Medical Center Hospital
2000
<b>Objective</b> To investigate whether placebo effects can experimentally be separated into the response to three components—assessment and observation, a therapeutic ritual (placebo treatment), supportive patient-practitioner relationship—and then progressively combined produce incremental clinical improvement in patients with irritable bowel syndrome. assess relative magnitude of these components. <b>Design</b> A six week single blind arm randomised controlled trial. <b>Setting</b>...
In prospective experimental studies in patients with asthma, it is difficult to determine whether responses placebo differ from the natural course of physiological changes that occur without any intervention. We compared effects a bronchodilator, two interventions, and no intervention on outcomes asthma.In double-blind, crossover pilot study, we randomly assigned 46 asthma active treatment an albuterol inhaler, sham acupuncture, or Using block design, administered one each these four...
Identifying patients who are potential placebo responders has major implications for clinical practice and trial design. Catechol-O-methyltransferase (COMT), an important enzyme in dopamine catabolism plays a key role processes associated with the effect such as reward, pain, memory learning. We hypothesized that COMT functional val158met polymorphism, was predictor of effects tested our hypothesis subset 104 from previously reported randomized controlled irritable bowel syndrome (IBS). The...
Patients in the placebo arms of randomized controlled trials (RCT) often experience positive changes from baseline. While multiple theories concerning such "placebo effects" exist, peculiarly, none has been informed by actual interviews patients undergoing treatment. Here, we report on a qualitative study (n = 27) embedded within RCT 262) with irritable bowel syndrome. Besides identical acupuncture treatment RCT, also received an additional set at beginning, midpoint, and end trial....
Although constipation is typically managed in an outpatient setting, there increasing trend the frequency of constipation-related hospital visits. The aim this study was to analyze trends related chronic (CC) United States with respect emergency department (ED) visits, patient and characteristics, associated costs.Data from 2006 2011, which (The International Classification Diseases, 9th Revision, Clinical Modification (ICD-9-CM) diagnosis codes 564.00-564.09) primary discharge diagnosis,...
Fecal microbiota transplantation (FMT) is an attractive strategy to correct microbial dysbiosis in diarrhea-predominant irritable bowel syndrome (IBS-D). Although the mechanism of FMT thought be bacterial engraftment, best approach achieve engraftment after IBS-D (and other diseases) not clear. We evaluated effect (with or without pretreatment with antibiotics) on gut microbiome and symptoms patients IBS-D. In this randomized, placebo-controlled, single-center study, 44 a least moderate...
Social interactions such as the patient-clinician encounter can influence pain, but underlying dynamic interbrain processes are unclear. Here, we investigated brain supporting social modulation of pain by assessing simultaneous activity (fMRI hyperscanning) from chronic patients and clinicians during video-based live interaction. Patients received painful nonpainful pressure stimuli either with a supportive clinician present (Dyadic) or in isolation (Solo). In half dyads, performed clinical...
OPINION article Front. Psychol., 10 August 2016Sec. Theoretical and Philosophical Psychology Volume 7 - 2016 | https://doi.org/10.3389/fpsyg.2016.01170
Brain activity concordance between patients and clinicians supports therapeutic alliance treatment relief of pain.
Peppermint oil is often used to treat irritable bowel syndrome (IBS); however, the overall quality of previous studies low, and findings have been heterogeneous. This study aimed compare effects peppermint vs placebo in relieving IBS symptoms.In a 6-week, randomized, double-blind, placebo-controlled trial at single academic center United States, individuals diagnosed with (Rome IV criteria), moderate severe symptoms based on Severity Scoring System (IBS-SSS score ≥175), were randomized...
Abstract Patient–clinician concordance in behavior and brain activity has been proposed as a potential key mediator of mutual empathy clinical rapport the therapeutic encounter. However, specific elements patient–clinician communication that may support brain-to-brain alliance are unknown. Here, we investigated how pain-related, directional facial between patients clinicians is associated with concordance. dyads interacted pain-treatment context, during synchronous assessment (fMRI...
• Itching was cited as a major symptom of their ocular disease by 49 (80%) the 61 patients with allergic conjunctivitis. Conjunctival scrapings from 51 (84%) demonstrated intact eosinophils or eosinophil granules. Eosinophil granules were useful and recognizable cytologic feature conjunctivitis even in absence eosinophils. We believe that history itching presence conjunctival are helpful diagnosing
ABSTRACT Objective There is growing evidence that open-label placebo (OLP) may be an efficacious treatment of chronic and functional conditions. However, patient-level predictors response to OLP have not been clearly identified. The aim this study evaluate the psychological compare double-blind (DBP) no-pill control (NPC). Methods This a secondary analysis data collected in 6-week randomized controlled trial evaluating effects irritable bowel syndrome (IBS). primary outcome was change IBS...
Background: Ethical informed consent to psychotherapy has recently been the subject of in-depth analysis among healthcare ethicists. Objective: This study aimed explore counselling and students’ views understanding about psychological treatments. Methods: Two focus groups were conducted with a total ten students enrolled in Masters course at British university. Questions concerned participants’ including judgments client capacity; kinds information that should be disclosed; how might...
The article reports on the results of an evaluation a school drug and alcohol prevention curriculum marketed under title, "Here's Looking at You, Two." Previous evaluations, unreported in literature having unresolved methodological problems, have found that while program appears effective transmitting information regarding abuse, it has not been changing underlying attitudes behaviors that, part, explain substance abuse. Employing more rigorous methodology, our examination relatively large...
We sought to identify the needs of adolescents and young adults with spina bifida their families. Using a qualitative research approach, we met focus group participants who provided us information about unmet needs. These efforts resulted in development two assessment questionnaires: one for people parents. Our results provide preliminary regarding these populations.
BACKGROUND A light-emitting diode (LED) photomodulation system can produce pulses of amber light expected to induce structural skin changes and reverse the effects photoaging. OBJECTIVE To reproduce encouraging results already published. METHODS AND MATERIALS Facial was exposed 588±10-nm-wavelength from a device for 40 seconds once week 8 weeks. Photographs, clinical assessment, subjective questionnaire were taken at baseline, last follow-up, 1 month after that. Thirty-six patients' pre-...
Objectives: This study is a 1-year follow-up investigation of the retention knowledge, attitudes and skills acquired after empathy training.Methods: Eight otolaryngology residents completed 5 assessment measures before training at 1-year. They attended 90-minute focus group assessing clinical usefulness training, factors that affect empathy.Results: Qualitative analysis revealed positive response to application practices. Quantitative analyses suggest improvement in was maintained (p =...
The interaction between C-X-C chemokine receptor type 4 (CXCR4) and its cognate ligand motif 12 (CXCL12) plays a critical role in regulating hematopoietic stem cell activation subsequent cellular mobilization. Extensive studies of these genes have been conducted mammals, but much less is known about the expression function CXCR4 CXCL12 non-mammalian vertebrates. In present study, we identify simultaneous orthologs epigonal organ (the primary tissue) little skate, Leucoraja erinacea. Genetic...