A5103275405- Complementary and Alternative Medicine Studies
- Acupuncture Treatment Research Studies
- Pain Management and Placebo Effect
- Traditional Chinese Medicine Studies
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Mindfulness and Compassion Interventions
- Neuroscience and Neuropharmacology Research
- Healthcare and Venom Research
- Memory and Neural Mechanisms
- Gastrointestinal motility and disorders
- Stress Responses and Cortisol
- Reproductive Health and Technologies
- Empathy and Medical Education
- Psychosomatic Disorders and Their Treatments
- Behavioral Health and Interventions
- Assisted Reproductive Technology and Twin Pregnancy
- Stroke Rehabilitation and Recovery
- Spaceflight effects on biology
- Eating Disorders and Behaviors
- Neurogenesis and neuroplasticity mechanisms
- Neuroinflammation and Neurodegeneration Mechanisms
- Dietary Effects on Health
- Menopause: Health Impacts and Treatments
- Pathogenesis and Treatment of Hiccups
- Music Therapy and Health
Harvard University
2015-2025
Beth Israel Deaconess Medical Center
2014-2025
Seattle Institute of Oriental Medicine
2024-2025
Oregon College of Oriental Medicine
2024
Maryland University of Integrative Health
2023
Hadassah Medical Center
2022
New England School of Acupuncture
2012-2021
MCPHS University
2016-2021
Boston University
2021
Nestlé (Switzerland)
2020
<b>Objective</b> To investigate whether placebo effects can experimentally be separated into the response to three components—assessment and observation, a therapeutic ritual (placebo treatment), supportive patient-practitioner relationship—and then progressively combined produce incremental clinical improvement in patients with irritable bowel syndrome. assess relative magnitude of these components. <b>Design</b> A six week single blind arm randomised controlled trial. <b>Setting</b>...
Objective: To determine whether placebo responses can be explained by characteristics of the patient, practitioner, or their interpersonal interaction. Methods: We performed an analysis videotape and psychometric data from a clinical trial patients with irritable bowel syndrome who were treated acupuncture in either warm empathic interaction (Augmented, n = 96), neutral (Limited, 97), waitlist control (Waitlist, 96). examined relationships between response a) patient personality...
Identifying patients who are potential placebo responders has major implications for clinical practice and trial design. Catechol-O-methyltransferase (COMT), an important enzyme in dopamine catabolism plays a key role processes associated with the effect such as reward, pain, memory learning. We hypothesized that COMT functional val158met polymorphism, was predictor of effects tested our hypothesis subset 104 from previously reported randomized controlled irritable bowel syndrome (IBS). The...
The purpose of this pilot study was to investigate the effects a yoga-based program on quality life, perceived stress, mindfulness, and self-compassion in young adults. These variables were measured 33 self-selected participants four-month residential yoga intervention before after program. Forty-three demographically matched controls completed same questionnaires at two time points with interval inbetween. Participation predicted increases life decreases mediated by mindfulness...
Patients in the placebo arms of randomized controlled trials (RCT) often experience positive changes from baseline. While multiple theories concerning such "placebo effects" exist, peculiarly, none has been informed by actual interviews patients undergoing treatment. Here, we report on a qualitative study (n = 27) embedded within RCT 262) with irritable bowel syndrome. Besides identical acupuncture treatment RCT, also received an additional set at beginning, midpoint, and end trial....
Gulf War Illness (GWI) is a chronic disorder affecting approximately 30% of the veterans who served in 1991 War. It characterised by constellation symptoms including musculoskeletal pain, cognitive problems and fatigue. The cause GWI not definitively known but exposure to neurotoxicants, prophylactic use pyridostigmine bromide (PB) pills, and/or stressors during deployment have all been suspected play some pathogenic role. Recent animal models suggested that neuroinflammatory mechanisms may...
This study aimed to compare the effects of true and sham acupuncture in relieving symptoms irritable bowel syndrome (IBS).A total 230 adult IBS patients (75 % females, average age: 38.4 years) were randomly assigned 3 weeks or (6 treatments) after a 3-week "run-in" with an "augmented" "limited" patient-practitioner interaction. A third arm included waitlist control group. The primary outcome was Global Improvement Scale (IBS-GIS) (range: 1 - 7); secondary outcomes Symptom Severity (IBS-SSS),...
Objective To qualitatively explore perceived physical and psychosocial effects overall patient experience associated with a 12-week tai chi (TC) intervention an education group in clinical trial of patients chronic heart failure (HF). Subjects Methods We randomized 100 systolic HF (NYHA Class 1–3, ejection fraction≤40%) to TC program or control. At 12-weeks, semi-structured interviews were conducted on random subset (n = 32; n 17 TC, 15 control), audiorecorded transcribed verbatim. Two...
Abstract Background There is increasing evidence suggesting that open-label placebo (OLP) an effective treatment for several medical conditions defined by self-report. However, little known about patients’ experiences with OLP, and no studies have directly compared in double-blind (DBP) conditions. Methods This study was nested a large randomized-controlled trial comparing the effects of OLP DBP treatments individuals irritable bowel syndrome (IBS). We randomly selected 33 participants...
Placebo medications, by definition, are composed of inactive ingredients that have no physiological effect on symptoms. Nonetheless, administration placebo in randomized controlled trials (RCTs) and clinical settings has been demonstrated to significant impact many physical psychological complaints. Until recently, conventional wisdom suggested patients must believe pills actually contain (or, at least, might possibly contain) active medication order elicit a response placebo. However,...
The present study was part of a group randomized controlled trial in which 7th grade students were assigned to yoga intervention or physical-education-as-usual. Sixteen randomly selected from the condition participate one-on-one interviews. Qualitative analyses revealed 13 themes that organized into two categories: Usability (student perceptions usefulness, learnability, and convenience intervention) Effect direct results intervention). Students reported both positive negative opinions yoga,...
Background: While acupuncture use and research publications are growing in the United States, we know little about chinese herbal medicine (ACHM) students' beliefs behaviors regarding research.