Guangzhou Li

ORCID: 0000-0002-9705-8537
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About
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Research Areas
  • Spinal Fractures and Fixation Techniques
  • Spine and Intervertebral Disc Pathology
  • Pelvic and Acetabular Injuries
  • Cervical and Thoracic Myelopathy
  • Scoliosis diagnosis and treatment
  • Cardiac Valve Diseases and Treatments
  • Aortic Disease and Treatment Approaches
  • Infective Endocarditis Diagnosis and Management
  • Spinal Cord Injury Research
  • Advanced biosensing and bioanalysis techniques
  • Electrochemical sensors and biosensors
  • Infectious Diseases and Tuberculosis
  • Pancreatitis Pathology and Treatment
  • Trauma Management and Diagnosis
  • Musculoskeletal pain and rehabilitation
  • Orthopedic Infections and Treatments
  • Shoulder and Clavicle Injuries
  • Pancreatic and Hepatic Oncology Research
  • RNA Research and Splicing
  • Hip and Femur Fractures
  • Heterotopic Ossification and Related Conditions
  • Neurofibromatosis and Schwannoma Cases
  • Anesthesia and Pain Management
  • Crystallization and Solubility Studies
  • Bone Tissue Engineering Materials

Suizhou Central Hospital
2024-2025

Union Hospital
2023-2025

Huazhong University of Science and Technology
2023-2025

Northwest University
2025

Affiliated Hospital of Southwest Medical University
2017-2024

Dalian Medical University
2023

Johns Hopkins University
2023

Chinese Institute for Brain Research
2023

Capital Medical University
2023

Beijing Shijitan Hospital
2023

Background Dementia poses a significant global health challenge, characterized by progressive cognitive decline and functional impairment. With the aging population, dementia prevalence is projected to surge, reaching an estimated 153 million cases 2050. While impact of traditional social isolation on risk has been extensively studied, influence digital isolation, phenomenon unique age, remains underexplored. Objective This study aimed investigate association between among older adults,...

10.2196/65379 article EN cc-by Journal of Medical Internet Research 2025-01-13

Aims A large number of surgical operations are available to treat osteochondral defects the knee. However, knee joint arthroplasty materials cannot completely mimic articular cartilage and subchondral bone, which may bring some obvious side effects. Thus, this study proposed a biocompatible repair material prepared from double-layer scaffold collagen nanohydroxyapatite (CHA), consisting hydrogel as upper layer scaffold, composite CHA lower scaffold. Methods The was prepared, properties...

10.1302/2046-3758.142.bjr-2024-0171.r1 article EN cc-by-nc-nd Bone and Joint Research 2025-02-27

The phenomenon of costal pain thoracic osteoporotic vertebral compression fractures (OVCFs) has been reported. However, to our knowledge, few reports with a larger sample size have analyzed the risk factors OVCFs. aim this study is evaluate in OVCFs patients. A total 425 consecutive patients were included retrospective study. Data on clinical and radiological parameters obtained evaluated. Independent t-tests chi-square tests used univariate analysis multivariate logistic regression was...

10.1038/s41598-025-88920-6 article EN cc-by-nc-nd Scientific Reports 2025-03-28

OBJECTIVE The correlation between the spinopelvic type and morphological characteristics of lumbar facet joints in patients with degenerative spondylolisthesis (DLS) was investigated. METHODS One hundred forty-two L4 DLS were enrolled (DLS group), 100 disc herniation without selected as control group (i.e., non–lumbar [NL] group). Morphological parameters L4–5 height angle measured on 3D reconstructed CT images; namely, joint (FJA), pedicle–facet (PFA), tropism, osteoarthritis (OA). slip...

10.3171/2022.11.spine22979 article EN Journal of Neurosurgery Spine 2023-01-23

As the first systematic examination of simple sequence repeats (SSRs) and guanine-cytosine (GC) distribution in intragenic intergenic regions ten primates, our study showed that SSRs GC displayed nonrandom for both regions, suggesting they have potential roles transcriptional or translational regulation. Our results suggest majority are distributed non-coding such as introns, TEs, regions. In these trinucleotide perfect (P) were most abundant type 5'UTRs CDSs, whereas, mononucleotide P-SSRs...

10.18632/aging.101025 article EN cc-by Aging 2016-09-16

Abstract Background Exploring the pathogenesis of osteoarthritis (OA) is important for its prevention, diagnosis, and treatment. Therefore, we aimed to construct novel signature genes (c-FRGs) combining cuproptosis-related (CRGs) with ferroptosis-related (FRGs) explore OA aid in Materials methods Differentially expressed c-FRGs (c-FDEGs) were obtained using R software. Enrichment analysis was performed a protein–protein interaction (PPI) network constructed based on these c-FDEGs. Then,...

10.1186/s13075-024-03328-3 article EN cc-by Arthritis Research & Therapy 2024-05-13

Atypical Hangman fractures (AHF) were first formally reported and considered to be more often associated with neurologic deficit in 1993. However, there is a paucity of literature focusing on these fractures. The purpose the retrospective study was introduce new classification scheme for AHF its application. Sixty-two patients identified. There 46 (74.2%, 46/62) patients, including 29 type I, 9 II, 5 IIa, 3 III (Levine–Edwards classification). Based fracture patterns, incidence, their impact...

10.1097/md.0000000000007492 article EN cc-by-nc Medicine 2017-07-01

When studying the altered expression of genes associated with cartilage regeneration by quantitative real-time RT-PCR (RT-qPCR), reference highly stable during different stages chondrocyte developmental are necessary to normalize gene accurately. Until now, no reports evaluating changes commonly used in rabbit articular have been published. In this study, defects were made cartilage, or without insulin-like growth factor 1 (IGF-1) treatment, create living environments. The stability and...

10.3390/ijms131114344 article EN cc-by International Journal of Molecular Sciences 2012-11-06

To observe the effects of occipitoaxial angle (O-C2 angle, OC2A) and posterior occipitocervical (POCA) selection on postoperative clinical efficacy lower cervical curvature in patients with acute acquired atlantoaxial dislocation after fusion (OCF).A total 150 healthy subjects without disease (healthy group) were randomly selected based gender age. Three spine surgeons measured OC2A POCA group averaged values. A 30 an average age 51.0 years (range, 18-70 years; 16 male 14 female) trauma or...

10.1111/os.12553 article EN cc-by Orthopaedic Surgery 2019-11-19

Herein, we design a simple and portable biosensing platform for the quantitative detection of cocaine based on target-triggered glucose release from TiO<sub>2</sub> nanotube array (TiNTA) with glucometer readout.

10.1039/c7tb00670e article EN Journal of Materials Chemistry B 2017-01-01

Abstract Background Irreversible neurological dysfunction (IND) is an adverse event after cervical spinal cord injury (CSCI). However, there still a shortage of objective criteria for the early prediction function. We aimed to screen independent predictors IND and use these findings construct nomogram that could predict development function in CSCI patients. Methods Patients with attending Affiliated Hospital Southwest Medical University between January 2014 March 2021 were included this...

10.1186/s12891-023-06570-z article EN cc-by BMC Musculoskeletal Disorders 2023-06-05

Rationale: Rod breakage after occipitocervical fusion (OCF) has never been described in a patient who undergone surgery for basilar invagination (BI) and atlantoaxial dislocation (AAD). Here, we present an unusual but significant case of revision to correct this complication. Patient concerns: A 32-year-old female presented with neck pain, unstable leg motion walking, also BI AAD. Her first was planned these conditions at the occipital junction (C3-4) using screw-rod system. At 31-month...

10.1097/md.0000000000010441 article EN cc-by-nc Medicine 2018-04-01
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