A5089122656- Mosquito-borne diseases and control
- Zoonotic diseases and public health
- Primate Behavior and Ecology
- Viral Infections and Vectors
- Virology and Viral Diseases
- Vector-borne infectious diseases
- Malaria Research and Control
- Rabies epidemiology and control
- Human-Animal Interaction Studies
- Poxvirus research and outbreaks
- Entomological Studies and Ecology
- Leptospirosis research and findings
- Herpesvirus Infections and Treatments
- Aquaculture disease management and microbiota
- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- COVID-19 Clinical Research Studies
- Bee Products Chemical Analysis
- Wildlife Ecology and Conservation
- Wildlife-Road Interactions and Conservation
- Water Quality and Pollution Assessment
- Plant and animal studies
- Agricultural pest management studies
- Livestock and Poultry Management
- Insect symbiosis and bacterial influences
Pan American Health Organization (Brasil)
2023-2024
Secretaria da Saúde
2003-2023
Governo do Estado do Rio Grande do Sul
2021-2022
Pontifícia Universidade Católica do Rio Grande do Sul
2018-2019
Centro de Estudos em Psicologia da Saúde
2012
Fundação Estadual de Produção e Pesquisa em Saúde
2011
Universidade de São Paulo
2010
Universidade do Estado do Pará
2010
Abstract Yellow fever virus (YFV) was isolated from Haemagogus leucocelaenus mosquitoes during an epizootic in 2001 the Rio Grande do Sul State southern Brazil. In October 2008, a yellow outbreak reported there, with nonhuman primate deaths and human cases. This latter led to intensification of surveillance measures for early detection YFV support vaccination programs. We report entomologic 2 municipalities that recorded deaths. Mosquitoes were collected at ground level, identified,...
Due to the risk of severe vaccine-associated adverse events, yellow fever vaccination in Brazil is only recommended areas considered at for disease. From September 2008 through June 2009, two outbreaks previously unvaccinated populations resulted 21 confirmed cases with 9 deaths (case-fatality, 43%) southern state Rio Grande do Sul and 28 11 (39%) Sao Paulo state. Epizootic non-human primates were reported before during outbreak. Over 5.5 million doses vaccine administered most affected...
Yellow fever (YF) is an arboviral disease which endemic to Brazil due a sylvatic transmission cycle maintained by infected mosquito vectors, non-human primate (NHP) hosts, and humans. Despite the existence of effective vaccine, recent sporadic YF epidemics have underscored concerns about vector surveillance, as very little known their spatial distribution. Here, we model map environmental suitability YF's main vectors in Brazil, Haemagogus spp. Sabethes spp., use human population NHP data...
Abstract The natural transmission cycle of Yellow Fever (YF) involves tree hole breeding mosquitoes and a wide array nonhuman primates (NHP), including monkeys apes. Some Neotropical (howler monkeys, genus Alouatta ) develop fatal YF virus (YFV) infections similar to those reported in humans, even with minimum exposure the infection. Epizootics wild may be indicating YFV circulation, surveillance such outbreaks wildlife is an important tool help prevent human In 2001, activities successfully...
In Brazil, epizootics among New World monkey species may indicate circulation of yellow fever (YF) virus and provide early warning risk to humans. Between 1999 2001, the southern Brazilian state Rio Grande do Sul initiated surveillance for YF in non-human primates inform vaccination human populations. Following a outbreak, we analyzed epizootic data assessed vaccine coverage, timeliness implementation unvaccinated From October 2008 through June 2009, was confirmed 67 municipalities State;...
Primates play an important role in ecosystem functioning and offer critical insights into human evolution, biology, behavior, emerging infectious diseases. There are 26 primate species the Atlantic Forests of South America, 19 them endemic. We compiled a dataset 5,472 georeferenced locations native 1 introduced species, as hybrids genera Callithrix Alouatta. The includes 700 communities, 8,121 single occurrences 714 estimates population sizes, covering most natural forest types tropical...
In recent decades, waves of yellow fever virus (YFV) from the Amazon Rainforest have spread and caused outbreaks in other regions Brazil, including Cerrado, a savannah-like biome through which YFV usually moves before arriving at Atlantic Forest. To identify vectors involved maintenance semiarid environments, an entomological survey was conducted after confirmation (YF) epizootics peak dry season Cerrado areas state Minas Gerais. total, 917 mosquitoes 13 taxa were collected tested for...
Despite the considerable morbidity and mortality of yellow fever virus (YFV) infections in Brazil, our understanding disease outbreaks is hampered by limited viral genomic data. Here, through a combination phylogenetic epidemiological models, we reconstructed recent transmission history YFV within different epidemic seasons Brazil. A suitability index based on highly domesticated Aedes aegypti was able to capture seasonality reported human infections. Spatial modeling revealed spatial...
A Febre Amarela (FA) é uma doença infecciosa aguda. No Brasil, a FA tem caráter sazonal, ocorrendo frequentemente entre os meses de janeiro abril, quando fatores ambientais propiciam o aumento da abundância dos vetores. Há diversos relatos sobre mortalidade primatas devido à FA, em especial do gênero Alouatta, mas há escassa informação disponível para verificar e quantificar danos causados às populações por eventos desta natureza. O presente estudo busca avaliar impacto surto ocorrido 2008...
The 2021 re-emergence of yellow fever in non-human primates the state Rio Grande do Sul (RS), southernmost Brazil, resulted death many howler monkeys (genus Alouatta) and led to declare a Public Health Emergency State Importance, despite no human cases reported. In this study, near-complete genomes virus (YFV) recovered from outbreak were sequenced examined aiming at better understanding phylogenetic relationships spatio-temporal dynamics distribution. Our results suggest that most likely...
Mosquito diversity was determined in an area located on the southern limit of Atlantic Forest north coast Rio Grande Sul State. Our major objective to verify composition, diversity, and temporal distribution mosquito fauna, influence temperature rainfall. Samplings were performed monthly between December, 2006 2008, three biotopes: forest, urban area, transition using CDC light traps a Nasci vacuum. A total 2,376 specimens collected, from which 1,766 (74.32%) identified as 55 different...
Free-ranging non-human primates (NHPs) can host a variety of pathogenic microorganisms, such as arboviruses, which include the yellow fever virus (YFV). This study aimed to detect circulation YF and other arboviruses in three wild Alouatta caraya populations forests southern Brazil.We collected 40 blood serum samples from 26 monkeys captured/recaptured up four times 2014 2016, searching for evidence by isolation, PCR, neutralization tests.Viral isolation genome detection were negative;...
A leptospirose apresenta no Estado do Rio Grande Sul uma grande diversidade de situações exposição, reservatórios, agentes etiológicos e quadros clínicos. O principal objetivo desse trabalho é identificar áreas maior risco possíveis componentes ecológicos da transmissão por meio agregação dados epidemiológicos em unidades espaciais que representem a sócio-ambiental Estado. Os 1.274 casos confirmados ocorridos 2001 foram georreferenciados município residência. mapas municípios sobrepostos aos...
In Brazil, the yellow fever virus (YFV) is maintained in a sylvatic cycle involving wild mosquitoes and non-human primates (NHPs). The endemic to Amazon region; however, waves of epidemic expansion reaching other Brazilian states sporadically occur, eventually causing spillovers humans.To report surveillance effort that led first confirmation YFV NHPs state Minas Gerais (MG), Southeast region, 2021.A network was created, encompassing technology smartphone applications coordinated actions...
INTRODUÇÃO: A vigilância entomológica tem se mostrado uma importante estratégia de monitoramento da fauna culicídeos com vistas a predizer o risco exposição espécies vetoras patógenos. Esse trabalho apresenta lista mosquitos identificados pela primeira vez no Rio Grande do Sul e discute potencial epidemiológico algumas ocorrentes Município Maquiné registros em outras regiões Estado. MÉTODOS: Os foram coletados aspirador Nasci armadilhas CDC, entre dezembro 2006 2008, área silvestre, rural...
Abstract Despite the considerable morbidity and mortality of Yellow fever virus (YFV) infections in Brazil, as well its widespread presence non-human primate host, our understanding disease outbreaks is hampered by limited viral genomic data. Determining timing spatial corridors YFV spread, geographic hotspots that link endemic north country with epidemic extra-Amazonian regions, are central to predicting preventing future outbreak events epidemics. Here, we tracked recent spread integrating...
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The genus Orthopoxvirus (OPXV) of the family Poxviridae comprises several viruses that are capable infecting a wide range hosts. One most widespread OPXVs is Vaccinia virus (VACV), which circulates in zoonotic cycles South America, especially Brazil, domestic and wild animals humans causing economic losses as well impacting public health. Despite this, little known about presence and/or exposure neotropical primates to orthopoxviruses country. In this study, we report results search for...
Unforeseen Plasmodium infections in the Atlantic Forest of Brazilian Extra-Amazonian region could jeopardise malaria elimination. A human case was registered Três Forquilhas, biome Rio Grande do Sul, after a 45 years' time-lapsed without any autochthonous notification this southern state. This finding represents expansion distribution areas Brazil and southernmost record South America decade. The coexistence bromeliad-breeding vector Anopheles (Kerteszia) cruzii non-human primates regularly...
Abstract The environments in which neotropical primates live have been undergoing an intense fragmentation process, constituting a major threat to the species' survival and causing resource scarcity, social isolation, difficulty dispersal, leaving populations increasingly vulnerable. Moreover, proximity of wild anthropized landscapes can change dynamics pathogens parasite‐host‐environment relationship, creating conditions that favor exposure different pathogens. To investigate previous...
Abstract The yellow fever virus (YFV) re-emergence in Rio Grande do Sul, Brazil, raised big concerns and led the state to declare a Public Health Emergency of State Importance. Here, we generated near-complete genomes from ongoing outbreak Southern aiming better understand phylogenetic aspects also spatio-temporal dynamics virus. Our findings highlight path dispersion Sul that YFV was reintroduced São Paulo through Paraná Santa Catarina states, at end 2020.