A5017117830- Essential Oils and Antimicrobial Activity
- Phytochemistry Medicinal Plant Applications
- Traditional and Medicinal Uses of Annonaceae
- Piperaceae Chemical and Biological Studies
- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Ethnobotanical and Medicinal Plants Studies
- Bee Products Chemical Analysis
- Morinda citrifolia extract uses
- Natural Antidiabetic Agents Studies
- Insect Pest Control Strategies
- Phytochemistry and Bioactivity Studies
- Oral microbiology and periodontitis research
- Psidium guajava Extracts and Applications
- Plant biochemistry and biosynthesis
- Botanical Research and Applications
- Meat and Animal Product Quality
- Hormonal and reproductive studies
- Microbial Metabolites in Food Biotechnology
- Pharmacological Effects and Assays
- Dental Health and Care Utilization
- Plant-Derived Bioactive Compounds
- Analytical Chemistry and Chromatography
- Plant and soil sciences
- Phytochemical compounds biological activities
National University of Engineering
2017-2025
Universidade Paulista
2010-2019
Universidade de São Paulo
2008-2010
Government of Catalonia
1985-1989
Grape pomace retains polyphenols in the peels and seeds after winemaking, which is indicative of high valorization potential this industrial waste. There strong evidence that phenolics are robust antioxidants confer photoprotection; thus, it rational to apply these active compounds from winemaking waste sunscreens, order increase UV protection. Despite importance class cosmetics public health, more efficacious strategies still needed overcome problems caused by photoinstability some filters....
ABSTRACT Background Recently, products with antibacterial properties derived from medicinal plants have increased as an alternative to conventional drugs. Thus, this study aimed formulate and evaluate the activity of experimental gel based on Grindelia tarapacana essential oil in a bacterial consortium. Material Methods The composition (EO) was determined using gas chromatography‐mass spectrometry (GC‐MS). EO against Streptococcus mutans ATCC 25175, sanguinis 10556, salivarius 13419...
Annona hypoglauca Mart., Annonaceae, popularly known as "beribá", was collected in flooded areas of the Amazonian Rain Forest. The crude extract obtained from this species found to be cytotoxic against human cancer cells. Chemical information on A. is scarce. So, present work aimed isolation and identification its alkaloids test their activity. Alkaloids were stem by acid–base partitioning remaining alkaloid-free partitioned with organic solvents. Gas chromatography–mass spectrometry GC/MS...
Enterococcus faecalis is an important pathogen associated with endodontic diseases, and its elimination control are of paramount importance, as it represents one the major causes failure in treatment disease. Twenty-five plant extracts obtained from Brazilian forests were found to be effective against planktonic E. subjected two traditional antibacterial assays, microdilution broth assay (MDBA) disk diffusion (DDA), using chlorhexidine (CHX) a control. Seven out 25 showed significant...
Previous studies analyzing 2,200 plant extracts indicated anti-enterococcal activity in 25 obtained from Brazilian forests' plants. In the present study, these were subjected to microdilution broth assay (MDBA) and disk diffusion (DDA) using planktonic Enterococcus faecalis ATCC® 29212TM submitted phytochemical analysis TLC HPLC. Three Ipomoea alba (MIC < 40 µg/mL), Diclinanona calycina µg/mL) Moronobea coccinea (40 MIC 80 µg/mL; MBC = showed significant bactericidal MDBA four I. (14.04 ±...
Laetia suaveolens, known as “casinga-cheirosa”, crude extract EB719 has previously shown cytotoxic activity against prostate cancer and squamous cell carcinoma. For the first time, seven molecules were isolated from its apolar—α-tocopherol (1) sitosterol (2)—and polar—3-O-caffeoylquinic acid (3), 4-O-caffeoylquinic (4), 5-O-feruloylquinic (5), hyperoside (6), isoquercitrin (7)—fractions. Acute toxicity was determined in a two-stage experiment: reduced number of Balb-c male mice received 5000...
Peptic ulcers are an important pathology, and the search for safer more effective treatment methods is of paramount importance. In this study, we assess gastroprotective effects hydroethanolic extract (HE) ethyl acetate fraction (EAF) from Kalanchoe pinnata leaves against ethanol/HCl-induced ulcer model in rats. The HE reduced gastric lesions by approximately 47% (400 mg/kg). A significant inhibition 50% was observed after pretreatment with EAF (200 Quercetrin quercetin...
Caries is a global public health problem, whose control requires the introduction of low-cost treatments, such as strong prevention strategies, minimally invasive techniques and chemical agents. Nature plays an important role source new antibacterial substances that can be used in caries, Brazil richest country terms biodiversity. Objective: In this study, disk diffusion method (DDM) was to screen over 2,000 Brazilian Amazon plant extracts against Streptococcus mutans. Material Methods:...
<ns3:p><ns3:bold>Background:</ns3:bold> Natural products with antibacterial potential have begun to be tested on biofilm models, bringing us closer understanding the response generated by complex microbial ecosystems of oral cavity. The objective this study was evaluate antibacterial, antibiofilm, and cytotoxic activities chemical compositions Peruvian propolis in an <ns3:italic>in vitro</ns3:italic> <ns3:italic>Streptococcus gordonii </ns3:italic>and<ns3:italic> Fusobacterium...
To evaluate the effectiveness of an experimental toothpaste based on
The organic extract EB689, obtained from the stem of Abarema auriculata (Benth.) Barneby & J.W.Grimes, Fabaceae, commonly known as “saboeiro-ferro”, was chemically studied, well its influence over behavioral effects such locomotion, emotionality and anxiety, after intra-peritonial administration were assessed. open-field elevated-plus maze used in experiments divided into two stages. first stage aimed for identification main behavior using a reduced number animals against half-fold diluted...
Laetia suaveolens (Poepp.) Benth., Salicaceae, popularly known as "casinga-cheirosa", "caferana", or "laranjinha", is native to Brazil but not endemic this country. A crude organic extract was obtained from the leaves and stem intraperitoneally administered in male Balb-c mice. Its behavioral effects were evaluated open field elevated plus maze a two-stage experiment that assessed ten different parameters related behavior locomotion, emotionality, anxiety. In first stage of experiment,...
Abstract The essential oils (EOs) obtained from the leaves of Iryanthera polyneura Ducke trees was chemically Assessed and tested for ability inhibiting growth Candida albicans , Enterococcus faecalis Escherichia coli Pseudomonas aeruginosa Staphylococcus aureus Streptococcus mutans S. sanguinis . oil also against breast (MCF‐7) prostate (PC‐3) cancer cell lines. Minimum bactericidal concentrations (MBCs) 50 % inhibition (IC ) values were obtained. EOs active Gram‐positive bacteria....
<ns3:p><ns3:bold>Background:</ns3:bold> Natural products with antibacterial potential have begun to be tested on biofilm models, bringing us closer understanding the response generated by complex microbial ecosystems of oral cavity. The objective this study was evaluate antibacterial, antibiofilm, and cytotoxic activities chemical compositions Peruvian propolis in an <ns3:italic>in vitro</ns3:italic> <ns3:italic>Streptococcus gordonii </ns3:italic>and<ns3:italic> Fusobacterium...
The present study aimed at evaluating the antibacterial activity of essential oils (EOs) obtained from leaves two Iryanthera ulei individuals, popularly known as ucuubarana. EOs were by hydrodistillation made with collected for 15 times same individual trees, resulting in sets named 10EO and 15EO. Yields showed a seasonal variation to #10, although no variations between both #10 #15 individuals have occurred. analyzed gas chromatography/mass spectroscopy (GC/MS) before evaluation against...
Thirteen samples of essential oils were obtained from the leaves ucuuba-chico-de-assis (Osteophloeum platyspermum, Myristicaceae), a long-lived pioneer tree Amazon rain forest. The 13 times collected same individual during 2 year period. analyzed using gas chromatography-mass spectrometry. Fifty terpenes identified and amount corresponded to 97.67 % total terpene amount, composed by 44.00 monoterpenes 56.00 sesquiterpenes. Major compounds β-pinene, limonene α-pinene in all oils. presence...
Anani, (Symphonia globulifera, Clusiaceae), known as chewstick, is a traditional plant occurring in Africa and Central South Americas that used against parasites microorganisms. Although its use popular some of these countries, there lack information related to influence over behavioral phenotype (BP).The objective this study evaluate the administration extract obtained from aerial organs Anani (EB1257) male Balb-c mice BP.Open cage observation, open field, elevated-plus maze apparatuses...
Introduction The need for new tools to treat infections is constantly growing due the possibilities of emerging diseases related environmental changes, climatic catastrophes, microorganism resistance, and human animal aging, leading an evident unbalance in planet’s health. Brazil contains most significant portion world biodiversity, a potential source antimicrobial natural products. Nonetheless, its environment, particularly forests, rainforests, under threat, meaning that rapidly conducted,...
Iryanthera polyneura (Myristicaceae) is popularly known as cumala-colorada, and can be found in the Amazon rain forest. The present study aimed evaluation of chemical composition essential oils (EOs) obtained from leaves I. throughout a two-year period order to correlate findings with seasonality climatic variation. Leaves were collected 15 times three different individuals, identified 22EO, 80EO 530EO, between years 2009 2011. EOs tested by gas-chromatography-mass spectrometry techniques....
<p>Chlorhexidine digluconate (CHX) is a gold standard drug in dentistry and widely used as reference both <italic>in vitro</italic> vivo</italic>experiments. Due to ease of access, mouth washes containing CHX 0.12% are substitute for aqueous solution laboratory experiments. Additionally, it well known that product flavor purposes, volatile compounds added formulations. Volatiles may improve wash's antibacterial ability. add potency the wash formulation. Compared with...