The main pathogenic feature of preeclampsia is maternal endothelial dysfunction that results from impaired angiogenesis and reduced repair capacity. In addition, risk associated with vitamin D deficiency. We hypothesized D(3) stimulates proangiogenic properties colony-forming cells (ECFCs). ECFCs were obtained cultured cord blood characterized by immunocytochemistry flow cytometry. Proliferation, total length tubule formation on Matrigel, expression VEGF mRNA, pro-matrix metalloproteinases...

The minimal use of instructional media in schools Kertamukti Village is caused by the low competence teachers information technology that supports learning. purpose electronic module participatory training to increase compiling and presenting interactive innovative learning media, so it expected be able attract attention interest students motivation. This involved at Village, Cimerak District, Pangandaran Regency. module-based was attended 9 from several schools, namely: SD Negeri 1 3...

The aim of this study was to evaluate the effects isoflavones on skin postmenopausal women.A prospective performed with 30 women before and immediately after end treatment 100 mg/day an isoflavones-rich, concentrated soy extract for six months. A punch in gluteal region sample collection program. Morphometric determination epidermal thickness, papillary index (wrinkling), amount dermal elastic collagen fibers assessed. In addition, number blood vessels also evaluated. paired Student's t-test...

OBJETIVO: avaliar a prevalência das queixas de distúrbios do sono pela polissonografia em amostra mulheres na pós-menopausa. MÉTODOS: foram selecionadas 33 pós-menopausa com média idade 56 anos, índice massa corporal médio 27, tempo 7,7 anos e Kupperman 17. Adotaram-se os seguintes critérios inclusão: entre 50 65anos, no mínimo um ano amenorréia FSH plasmático superior ou igual 30 mU/mL, sem uso terapia hormonal prévia exames laboratoriais normais. Foram excluídas as pacientes doenças...

OBJECTIVE: The aim of this study was to evaluate the action conjugated equine estrogens and tamoxifen on morphology thyroid gland in ovariectomized (OVx) rats. METHODS: Conjugated (CEE), clinically used as estrogen therapy, is a complex formulation containing multiple that decrease menopausal symptoms. Thirty rats were randomly divided into 3 treatment groups: GI, vehicle (propylene glycol); GII, CEE 200 µg/kg per day; GIII, 1 mg/kg day. Another group 10 with intact ovaries (GIV) included,...

OBJECTIVE: To evaluate clinically, and with laboratory, tests, women polycystic ovary syndrome (PCO). PATIENTS: One hundred twelve PCO were studied. METHODS: The following data was recorded: Current age; age at menarche; menstrual irregularity, occurrence of similar cases in the family; fertility, obstetric history; body mass index (BMI); presence hirsutism. Serum measurements follicle stimulating hormone (FSH), luteinizing (LH), prolactin, free testosterone, dehydroepiandrosterone sulfate...

OBJETIVO: analisar os efeitos da isoflavona e do estrogênio sobre a qualidade de vida mulheres na pós-menopausa. MÉTODOS: realizou-se estudo randomizado, duplo-cego, com 79 pacientes, amenorréia 12 meses, idade superior 40 anos índice massa corporal (IMC) 30 kg/m². As foram aleatoriamente divididas em dois grupos tratamento: GECP recebeu duas cápsulas, via oral, 12/12 horas, uma contendo 0,625 mg estrogênios conjugados eqüinos e, outra, placebo (n=33); GECS cápsulas 150 extrato soja, 60...

Objetivo: Identificar o conhecimento sobre a Higiene do Sono em mulheres que frequentavam um ambulatorio de climaterio. Metodo: Os dados foram obtidos pelo preenchimento questionario higiene sono, por 72 na perimenopausa/pos-menopausa, sendo 30 eram atendidas geral climaterio e 42 “disturbios sono”. Foram realizadas analises estatisticas frequencia simples , diferenciando entre ou nao da sono comparacao os subgrupos qui-quadrado. Resultados: No grupo total foi identificado 79,2 % delas...

Studies on the thyroid-hormone receptors in nuclei of developing chick brain revealed a single class binding sites for tri-iodothyronine (T3) and thyroxine (T4) at all embryonic adult ages. High-affinity [Ka = (1.85-3.3) X 10(9)M-1 (0.3-0.6 × T3 T4 respectively] were detected as early day 7 development; their level increased progressively rapidly until 13, thereafter value remained essentially constant during development. Occupancy receptor site with endogenous hormone was 75-90% 7-11 days,...

Hepatic lipase (HL), an enzyme present in the hepatic sinusoids, is responsible for lipolysis of lipoproteins. Human HL contains four polymorphic sites: G-250A, T-710C, A-763G, and C-514T single-nucleotide polymorphism (SNPs). The last focus current study. genotypes associated with are CC (normal homozygous - W), CT (heterozygous H), TT (minor-allele M). activity significantly impaired individuals genotypes. A total 58 post-menopausal women were studied. subjects hysterectomized receiving...

In this study, we evaluated genetic factors related to the mineral density during post-menopause.We 110 women in first 5 years post-menopause, without previous hormone replacement therapy.Cytochrome P450 17 (CYP17) (rs743572), catechol-O-methyl transferase (COMT) (rs4680), and estrogen receptor 1 (ESR1) (rs9322331) were examined for presence of polymorphisms.Clinical data collected by anamnesis; all patients had osseous densitometry using a lunar instrument determine lumbar column...

The aim was to analyze the effect of adipose tissue transplantation on growth differentiation factor-9 (GDF-9), insulin factor 1 receptor (IGF1R), and leptin (LEPR) protein expression in ovaries obese anovulatory mice. Leptin-deficient female (ob/ob) wild-type mice were divided into untreated ob/ob gonadal white transplanted mice, with evaluation after 7, 15, 45 days compared control corporal weight glycemia levels increased group concomitant polymicrocyst formation abundant estrone,...

OBJETIVO: avaliar os efeitos de altas doses genisteína sobre o epitélio mamário ratas adultas. MÉTODOS: após 28 dias da ooforectomia, cinquenta adultas foram divididas em cinco grupos, a saber: um controle (Ctrl), três que receberam (GEN) nas 46 mg/kg (GEN46), 125 (GEN125) e 250 (GEN250), recebeu estrogênios conjugados equinos na dose 50 µg/kg (ECE). As substâncias administradas diariamente durante 30 consecutivos por gavagem última semana tratamento foi efetuado exame colpocitológico sete...

To investigate the association between CYP17alpha gene polymorphism and hot flushes in postmenopausal women.Ninety-three non-hysterectomized, women were enrolled this study. Vasomotor symptoms assessed at baseline visit based on information provided by each participant. The genotypic of was analyzed PCR-RFLP assay using genomic DNA isolated from peripheral blood lymphocytes.Thirty-six reported mild intensity, 25 moderate intensity 32 severe intensity. There no significant difference severity...

We aim to assess the effects of metformin treatment on metabolic and endocrine parameters genes expression related insulin-responsive pathway in polycystic ovary syndrome (PCOS). This study comprises twenty-eight obese mice divided into three metformin-treated groups for seven twenty days eight nonobese nontreated ones. found a significant decrease glycemia after at twenty. However, we did not observe differences body weight measurement. Histologically, observed follicular development with...

The purpose of this study is to provide an overview and strategies that can be carried out by teachers parents in fostering children maintain cleanliness health. This research uses a qualitative approach literature study. data sources for are at the Cemerlang Insan Early Childhood Education Institute Magetan literacy studies come from relevant studies. results indicate personal hygiene health activities PAUD consist three parts, namely (1) Self-cleaning, (2) Consumption nutritious food, (3)...