A5027894796- Estrogen and related hormone effects
- Ovarian function and disorders
- Reproductive System and Pregnancy
- Reproductive Biology and Fertility
- Phytoestrogen effects and research
- Organ Transplantation Techniques and Outcomes
- Endometriosis Research and Treatment
- Cancer Risks and Factors
- Cardiac Ischemia and Reperfusion
- Birth, Development, and Health
- Proteoglycans and glycosaminoglycans research
- Circadian rhythm and melatonin
- Hormonal and reproductive studies
- Reproductive Physiology in Livestock
- Urological Disorders and Treatments
- Liver Disease and Transplantation
- Pregnancy and Medication Impact
- Liver Disease Diagnosis and Treatment
- Clinical Nutrition and Gastroenterology
- Urinary Bladder and Prostate Research
- Pelvic floor disorders treatments
- Stress Responses and Cortisol
- Voice and Speech Disorders
- Fatty Acid Research and Health
- Tissue Engineering and Regenerative Medicine
Universidade Federal de São Paulo
2015-2024
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2016-2024
Universidade de São Paulo
1984-2023
Istituti di Ricovero e Cura a Carattere Scientifico
2023
University College London
2023
Aarhus University Hospital
2023
University of Bologna
2023
Cleveland Clinic
2023
University of Alabama at Birmingham
2022
University of Ottawa
2018
This study evaluated the effects of bone marrow-derived mesenchymal stem cells (BMSCs) or their conditioned medium (CM) on repair and prevention Acute Kidney Injury (AKI) induced by gentamicin (G). Animals received daily injections G up to 20 days. On 10th day, BMSCs, CM, CM+trypsin, CM+RNase exosome-like microvesicles extracted from CM were administered. In groups, animals BMSCs 24 h before 5th day treatment. Creatinine (Cr), urea (U), FENa cytokines quantified. The kidneys using...
Stroke is the most common cause of motor disabilities and a major mortality worldwide. Adult stem cells have been shown to be effective against neuronal degeneration through mechanisms that include both recovery neurotransmitter activity decrease in apoptosis oxidative stress. We chose lineage stroke-prone spontaneously hypertensive rat (SHRSP) as model for cell therapy. SHRSP rats can develop such severe hypertension they generally suffer stroke at approximately 1 year age. The aim this...
Hormonal and metabolic factors may influence endometrial quality interfere with the action of progesterone. Therefore, aim our study was to address this issue. Participants were recruited from an outpatient reproductive endocrinology clinic at academic tertiary medical care centre. All subjects underwent biopsy (EB) in follicular phase cycle prior treatment. Thereafter, they treated micronized progesterone (400 mg/day × 10 days intravaginally) 14–28 next cycle. A second EB performed between...
Autophagy is a survival pathway wherein non-functional proteins and organelles are degraded in lysosomes for recycling energy production. Therefore, autophagy fundamental the maintenance of cell viability, acting as quality control process that prevents accumulation unnecessary structures oxidative stress. Increasing evidence has shown dysfunction related to several pathologies including neurodegenerative diseases cancer. Moreover, recent studies have plays an important role bone...
The aim of this study was to evaluate the effects isoflavones on skin postmenopausal women.A prospective performed with 30 women before and immediately after end treatment 100 mg/day an isoflavones-rich, concentrated soy extract for six months. A punch in gluteal region sample collection program. Morphometric determination epidermal thickness, papillary index (wrinkling), amount dermal elastic collagen fibers assessed. In addition, number blood vessels also evaluated. paired Student's t-test...
Abstract One important concern in the treatment of diabetes is maintenance glycemic levels and prevention diabetic nephropathy. Inducible heme oxygenase 1 (HO-1) a rate-limiting enzyme thought to have antioxidant cytoprotective roles. The goal present study was analyze effect HO-1 induction chronically hyperglycemic rats. rats were divided into two groups: one group, called STZ, given single injection streptozotocin; other group streptozotocin as well daily injections hemin, an inducer, over...
The current study was conducted to investigate the relationship between melatonin and chronic anovulation. Adult (3-4 months old) female Wistar rats were submitted pinealectomy: group I: pinealectomized ovariectomized melatonin-treated (N = 10); II: placebo-treated 12); III: light-treated placebo-treated(N 10) or maintained under continuous light; IV: light, 22); V: VI: light 10). In order assess ovarian modifications, unilateral ovariectomy performed during fourth month in groups I, II, IV,...
A major concern in ovarian transplants is substantial follicle loss during the initial period of hypoxia. Adipose tissue-derived stem cells (ASCs) have been employed to improve angiogenesis when injected into ischemic tissue. This study evaluated safety and efficacy adipose therapy freshly grafted ovaries 30 days after injection. Rat ASCs (rASCs) obtained from transgenic rats expressing green fluorescent protein (GFP)-(5 × 104 cells/ovary) were topic (intact) or twelve-week-old adult female...
ABSTRACT Lidocaine blocks nociceptive fibers, preventing initial wound signaling and mast cell degranulation. It is hypothesized that epinephrine buffer affect the healing by potentiating lidocaine blockage. This double‐blind, randomized, self‐controlled study investigated this possibility using male Wistar rats, which were injected with 2 mL of different solutions into left right sides back. Then, each side was incised sutured. Sixty rats divided in three groups: saline solution (SS)...