A5040123565- Plant-Microbe Interactions and Immunity
- Plant tissue culture and regeneration
- Phytochemical compounds biological activities
- Plant Stress Responses and Tolerance
- Microbial Natural Products and Biosynthesis
- Plant biochemistry and biosynthesis
- Allelopathy and phytotoxic interactions
- Phytochemistry and Biological Activities
- SARS-CoV-2 and COVID-19 Research
- Bioactive Compounds and Antitumor Agents
- Essential Oils and Antimicrobial Activity
- SARS-CoV-2 detection and testing
- Legume Nitrogen Fixing Symbiosis
- Transgenic Plants and Applications
- Fungal Biology and Applications
- Biosensors and Analytical Detection
- Plant and fungal interactions
- Plant Gene Expression Analysis
- Plant Molecular Biology Research
- Cancer-related Molecular Pathways
- Plant Parasitism and Resistance
- Genomics and Phylogenetic Studies
- Nematode management and characterization studies
- Plant Pathogens and Fungal Diseases
- Chemical synthesis and alkaloids
Indian Institute of Integrative Medicine
2015-2024
Academy of Scientific and Innovative Research
2015-2024
Council of Scientific and Industrial Research
2015-2024
University of Jammu
2017
Centre for Cellular and Molecular Biology
2004-2016
University of Missouri
2004
Genes normally resident in euchromatic domains are silenced when packaged into heterochromatin, as exemplified Drosophila melanogaster by position effect variegation (PEV). Loss-of-function mutations resulting suppression of PEV have identified critical components including proteins HP1, HP2, and histone H3 lysine 9 methyltransferase. Here, we demonstrate that this silencing is dependent on the RNA interference machinery, using tandem mini-white arrays white transgenes heterochromatin to...
Plant growth promoting rhizobacteria (PGPRs) are very effective in immobilization of heavy metals and reducing their translocation plants via precipitation, complex formation adsorption. The present study was therefore designed to understand the role Pseudomonas aeruginosa Burkholderia gladioli mitigation Cd stress (0.4 mM) 10-days old L. esculentum seedlings. work investigated characteristics, photosynthetic pigments, metal tolerance index, uptake contents chelating compounds (protein bound...
Chromium (Cr) toxicity leads to the enhanced production of reactive oxygen species (ROS), which are extremely toxic plant and must be minimized protect from oxidative stress. The potential plant-growth-promoting rhizobacteria (PGPR) earthworms in growth development has been extensively studied. present study was aimed at investigating effect two PGPR (Pseudomonas aeruginosa Burkholderia gladioli) along with (Eisenia fetida) on antioxidant defense system Brassica juncea seedlings under Cr...
Natural products have extensively contributed toward the discovery of new leads for Alzheimer's disease. During our search inhibitors cholinesterase enzymes from natural sources, ethyl acetate (EtOAc) extract Rumex abyssinicus Jacq was identified as a dual inhibitor with IC50 values 2.7 and 11.4 μg/mL against acetylcholinesterase (AChE) butyrylcholinesterase (BChE), respectively. The phytochemical investigation EtOAc has resulted in isolation four anthraquinones, namely, helminthosporin,...
Rohitukine (1), a chromone alkaloid isolated from Indian medicinal plant Dysoxylum binectariferum, has inspired the discovery of flavopiridol and riviciclib, both which are bioavailable only via intravenous route. With objective to address oral bioavailability issue this scaffold, four series rohitukine derivatives were prepared screened for Cdk inhibition cellular antiproliferative activity. The 2,6-dichloro-styryl derivative IIIM-290 (11d) showed strong Cdk-9/T1 (IC50 1.9 nM) kinase...
Present study relates to the effect of valproic acid, an epigenetic modifier on metabolic profile Aspergillus fumigatus (GA-L7), endophytic fungus isolated from Grewia asiatica L. Seven secondary metabolites were A. (GA-L7) which identified as: pseurotin A, D, F2, fumagillin, tryprostatin C, gliotoxin and bis(methylthio)gliotoxin. Addition acid in growth medium resulted alteration with enhanced production a metabolite, fumiquinazoline C by tenfolds. In order assess biosynthetic pathway we...
The environmental stress, biotic as well abiotic, is the main cause of decreased growth and crop production. One stress-causing agents in plants are parasitic nematodes responsible for loss. Jasmonic acid (JA) recognized one signaling molecules defense-related responses plants, however, its role under nematode infestation unclear. Therefore, present study was planned to traverse JA boosting activities antioxidative enzymes tomato seedlings during inoculation. Application declined oxidative...
Abstract Epithelial to mesenchymal transitions (EMT) is a preparatory process for cancer cells attain motility and further metastasis distant sites. Majority of DNA damaging drugs have shown develop EMT as one the major mechanisms drug resistance. Here we sought understand resistance/survival instincts during initial phase treatment. We provide tangible evidence stimulation factors in Apc knockout colorectal carcinoma model. Our results implied that CPT-treated cohorts depicted increased...